rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q01484 | 3957 | ANK2_HUMAN Ankyrin-2 OS=Homo sapiens (Human).... | 83 | 0.67 | 37.7 | 29 | 52 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro. | 32 | Q9BXX2 | 1392 | AN30B_HUMAN Ankyrin repeat domain-containing ... | 143 | 0.001 | 46.6 | 27 | 45 | | | | | | | | | | | | | | | | | | | | | | 33 | P70569 | 1846 | MYO5B_RAT Unconventional myosin-Vb OS=Rattus ... | 77 | 0.05 | 41.2 | 26 | 48 | GO:0043197; C:dendritic spine; IDA:RGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IMP:RGD. | | | | | | | | | | GO:0015031; P:protein transport; IMP:RGD.::GO:0032880; P:regulation of protein localization; IMP:RGD. | 34 | Q8N8V4 | 417 | ANS4B_HUMAN Ankyrin repeat and SAM domain-con... | 142 | 0.002 | 45.4 | 30 | 46 | | | | | | | | | | | | | | | | | | | | | | 35 | A0M8T5 | 1658 | CTTB2_FELCA Cortactin-binding protein 2 OS=Fe... | 132 | 0.002 | 45.8 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 36 | P21271 | 1818 | MYO5B_MOUSE Unconventional myosin-Vb OS=Mus m... | 117 | 0.027 | 42 | 21 | 45 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 37 | Q07E28 | 1658 | CTTB2_NEONE Cortactin-binding protein 2 OS=Ne... | 132 | 0.003 | 45.4 | 29 | 46 | | | | | | | | | | | | | | | | | | | | | | 38 | Q6P9K8 | 1431 | CSKI1_MOUSE Caskin-1 OS=Mus musculus (Mouse).... | 133 | 0.003 | 45.1 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 39 | Q8VHK2 | 1430 | CSKI1_RAT Caskin-1 OS=Rattus norvegicus (Rat)... | 133 | 0.003 | 45.1 | 27 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IDA:RGD. | | | | | | | | | | GO:0007165; P:signal transduction; IPI:UniProtKB. | 40 | Q3UMR0 | 1048 | ANR27_MOUSE Ankyrin repeat domain-containing ... | 116 | 6.1 | 34.3 | 24 | 43 | | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 41 | Q811D2 | 1581 | ANR26_MOUSE Ankyrin repeat domain-containing ... | 133 | 0.005 | 44.7 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 42 | Q13625 | 1128 | ASPP2_HUMAN Apoptosis-stimulating of p53 prot... | 100 | 0.006 | 44.3 | 31 | 50 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 43 | Q9Z2X2 | 231 | PSD10_MOUSE 26S proteasome non-ATPase regulat... | 78 | 0.007 | 42.7 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 44 | Q495B1 | 522 | AKD1A_HUMAN Ankyrin repeat and death domain-c... | 65 | 0.22 | 38.9 | 32 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 45 | Q8CG79 | 1128 | ASPP2_MOUSE Apoptosis-stimulating of p53 prot... | 100 | 0.007 | 43.9 | 30 | 51 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; IMP:MGI.::GO:0009792; P:embryo development ending in birth or egg hatching; IGI:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:MGI. | 46 | O75832 | 226 | PSD10_HUMAN 26S proteasome non-ATPase regulat... | 78 | 0.008 | 42.4 | 32 | 51 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 47 | Q8WXD9 | 1431 | CSKI1_HUMAN Caskin-1 OS=Homo sapiens (Human).... | 133 | 0.008 | 43.9 | 27 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; ISS:UniProtKB. | 48 | Q86WC6 | 154 | PPR27_HUMAN Protein phosphatase 1 regulatory ... | 44 | 0.013 | 40.8 | 48 | 59 | | | | | | | | | | | GO:0019902; F:phosphatase binding; IDA:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 49 | Q875X3 | 1567 | MYO2A_NAUCC Myosin-2A OS=Y-12630) (Yeast) (Sa... | 144 | 0.015 | 43.1 | 28 | 47 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 50 | G0LXV8 | 1351 | LATA_LATHA Alpha-latrotoxin-Lh1a OS=Latrodect... | 55 | 1 | 37 | 36 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW. | 51 | P23631 | 1401 | LATA_LATTR Alpha-latrotoxin-Lt1a OS=(Latrodec... | 78 | 0.016 | 42.7 | 33 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW. | 52 | Q9ULV0 | 1848 | MYO5B_HUMAN Unconventional myosin-Vb OS=Homo ... | 77 | 0.017 | 42.7 | 26 | 49 | GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; TAS:Reactome.::GO:0017137; F:Rab GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB.::GO:0006833; P:water transport; TAS:Reactome. | 53 | Q923M0 | 524 | PP16A_MOUSE Protein phosphatase 1 regulatory ... | 127 | 0.28 | 38.5 | 28 | 45 | GO:0005829; C:cytosol; TAS:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 54 | Q96AX9 | 1013 | MIB2_HUMAN E3 ubiquitin-protein ligase MIB2 O... | 66 | 0.017 | 42.7 | 36 | 50 | GO:0005768; C:endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. | 55 | Q8NFD2 | 765 | ANKK1_HUMAN Ankyrin repeat and protein kinase... | 69 | 6.3 | 34.3 | 35 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | Q876G9 | 1568 | MYO2_SACBA Myosin-2 OS=Saccharomyces bayanus ... | 114 | 0.023 | 42.4 | 26 | 49 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 57 | Q9TXQ1 | 2276 | PME5_CAEEL Poly(ADP-ribose) polymerase pme-5 ... | 46 | 0.029 | 42 | 41 | 54 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043069; P:negative regulation of programmed cell death; IMP:WormBase.::GO:0006471; P:protein ADP-ribosylation; IEA:InterPro.::GO:0010332; P:response to gamma radiation; IEP:WormBase. | 58 | Q9J4Z5 | 436 | V245_FOWPN Putative ankyrin repeat protein FP... | 141 | 0.033 | 41.6 | 27 | 46 | | | | | | | | | | | | | | | | | | | | | | 59 | A1X157 | 1666 | CTTB2_ECHTE Cortactin-binding protein 2 OS=Ec... | 132 | 0.034 | 42 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 60 | A2A2Z9 | 1011 | AN18B_HUMAN Ankyrin repeat domain-containing ... | 136 | 0.035 | 41.6 | 29 | 42 | | | | | | | | | | | | | | | | | | | | | | 61 | Q54KA7 | 986 | SECG_DICDI Ankyrin repeat, PH and SEC7 domain... | 123 | 0.072 | 40.8 | 28 | 42 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. |