| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q99J82 | 452 | ILK_RAT Integrin-linked protein kinase OS=Rat... | 57 | 2.5 | 35.4 | 28 | 53 | GO:0005911; C:cell-cell junction; IDA:RGD.::GO:0043034; C:costamere; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IMP:RGD.::GO:0007050; P:cell cycle arrest; IMP:RGD.::GO:0043206; P:fibril organization; IMP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; IMP:RGD.::GO:0032288; P:myelin assembly; IMP:RGD.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:RGD.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:RGD. | 212 | O55222 | 452 | ILK_MOUSE Integrin-linked protein kinase OS=M... | 57 | 2.5 | 35.4 | 28 | 53 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:MGI.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL. | 213 | Q13418 | 452 | ILK_HUMAN Integrin-linked protein kinase OS=H... | 57 | 2.5 | 35.4 | 28 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB. | 214 | Q6P1S6 | 118 | MTPN_XENTR Myotrophin OS=Xenopus tropicalis (... | 40 | 2.5 | 33.5 | 35 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 215 | Q08353 | 314 | IKBA_PIG NF-kappa-B inhibitor alpha OS=Sus sc... | 90 | 2.5 | 35 | 28 | 43 | GO:0005634; C:nucleus; ISS:AgBase. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; ISS:AgBase.::GO:0008139; F:nuclear localization sequence binding; ISS:AgBase.::GO:0031625; F:ubiquitin protein ligase binding; ISS:AgBase. | | | | | | | | | | GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:AgBase.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:AgBase.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:AgBase.::GO:0000060; P:protein import into nucleus, translocation; ISS:AgBase.::GO:0042127; P:regulation of cell proliferation; ISS:AgBase.::GO:0043330; P:response to exogenous dsRNA; ISS:AgBase. | 216 | Q5R5V4 | 452 | ILK_PONAB Integrin-linked protein kinase OS=P... | 57 | 2.6 | 35.4 | 28 | 53 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 217 | Q91ZT9 | 288 | ASB8_MOUSE Ankyrin repeat and SOCS box protei... | 138 | 2.6 | 35 | 31 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 218 | Q3SWY2 | 452 | ILK_BOVIN Integrin-linked protein kinase OS=B... | 57 | 2.6 | 35.4 | 28 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 219 | Q53RE8 | 183 | ANR39_HUMAN Ankyrin repeat domain-containing ... | 61 | 2.6 | 34.3 | 34 | 49 | | | | | | | | | | | | | | | | | | | | | | 220 | Q96KQ7 | 1210 | EHMT2_HUMAN Histone-lysine N-methyltransferas... | 138 | 2.8 | 35.4 | 22 | 40 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046976; F:histone methyltransferase activity (H3-K27 specific); ISS:UniProtKB.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB. | 221 | Q9W0T5 | 956 | PYX_DROME Transient receptor potential channe... | 87 | 9.3 | 33.9 | 32 | 49 | GO:0016021; C:integral to membrane; IC:UniProtKB. | | | | | | | | | | GO:0005261; F:cation channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0048060; P:negative gravitaxis; IMP:FlyBase.::GO:0051290; P:protein heterotetramerization; NAS:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB. | 222 | Q08E43 | 288 | ASB8_BOVIN Ankyrin repeat and SOCS box protei... | 138 | 2.9 | 34.7 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 223 | P25963 | 317 | IKBA_HUMAN NF-kappa-B inhibitor alpha OS=Homo... | 90 | 3 | 35 | 28 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0008139; F:nuclear localization sequence binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0070417; P:cellular response to cold; NAS:BHF-UCL.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:BHF-UCL.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043392; P:negative regulation of DNA binding; NAS:UniProtKB.::GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.::GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.::GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 224 | P39010 | 764 | AKR1_YEAST Palmitoyltransferase AKR1 OS=Sacch... | 98 | 3 | 35.4 | 24 | 47 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016409; F:palmitoyltransferase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0018345; P:protein palmitoylation; IDA:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD. | 225 | Q6S8J3 | 1075 | POTEE_HUMAN POTE ankyrin domain family member... | 61 | 3.1 | 35.4 | 31 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro. | | | | | | | | | | | 226 | Q6NSI1 | 321 | AR26L_HUMAN Putative ankyrin repeat domain-co... | 84 | 3.1 | 35 | 29 | 44 | | | | | | | | | | | | | | | | | | | | | | 227 | A5A3E0 | 1075 | POTEF_HUMAN POTE ankyrin domain family member... | 61 | 3.2 | 35.4 | 31 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro. | | | | | | | | | | | 228 | Q63746 | 314 | IKBA_RAT NF-kappa-B inhibitor alpha OS=Rattus... | 90 | 3.3 | 34.7 | 28 | 43 | GO:0005829; C:cytosol; IDA:RGD.::GO:0033256; C:I-kappaB/NF-kappaB complex; IC:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0051059; F:NF-kappaB binding; IPI:RGD. | | | | | | | | | | GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:RGD. | 229 | Q9D2X0 | 183 | ANR39_MOUSE Ankyrin repeat domain-containing ... | 61 | 3.4 | 34.3 | 34 | 49 | | | | | | | | | | | | | | | | | | | | | | 230 | Q6KAE5 | 496 | XB32_ORYSJ Probable E3 ubiquitin-protein liga... | 106 | 3.4 | 35 | 31 | 40 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 231 | Q6RI86 | 1125 | TRPA1_RAT Transient receptor potential cation... | 30 | 3.5 | 35 | 43 | 73 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 232 | Q69ZU8 | 712 | ANKR6_MOUSE Ankyrin repeat domain-containing ... | 74 | 3.5 | 35 | 34 | 46 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:MGI.::GO:2000096; P:positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway; IDA:MGI. | 233 | O75762 | 1119 | TRPA1_HUMAN Transient receptor potential cati... | 50 | 9.3 | 33.9 | 32 | 52 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | | | | | | | | | | | | 234 | Q80T11 | 461 | USH1G_MOUSE Usher syndrome type-1G protein ho... | 95 | 3.5 | 35 | 33 | 47 | GO:0015629; C:actin cytoskeleton; IDA:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060113; P:inner ear receptor cell differentiation; IMP:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI. | 235 | Q9Z1E3 | 314 | IKBA_MOUSE NF-kappa-B inhibitor alpha OS=Mus ... | 90 | 3.5 | 34.7 | 28 | 43 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:MGI.::GO:0070427; P:nucleotide-binding oligomerization domain containing 1 signaling pathway; IDA:MGI.::GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:MGI.::GO:0000060; P:protein import into nucleus, translocation; IDA:MGI.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0032495; P:response to muramyl dipeptide; IDA:MGI.::GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:MGI. | 236 | Q7Z020 | 1296 | TRPA1_DROME Transient receptor potential cati... | 60 | 3.6 | 35 | 33 | 55 | GO:0016021; C:integral to membrane; IC:UniProtKB. | | | | | | | | | | GO:0005261; F:cation channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:FlyBase.::GO:0042745; P:circadian sleep/wake cycle; IMP:FlyBase.::GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IMP:FlyBase.::GO:0007613; P:memory; IMP:FlyBase.::GO:0043052; P:thermotaxis; IDA:FlyBase. | 237 | Q8BLA8 | 1125 | TRPA1_MOUSE Transient receptor potential cati... | 50 | 6.6 | 34.3 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IDA:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0042493; P:response to drug; IDA:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.::GO:0048265; P:response to pain; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI. | 238 | Q495M9 | 461 | USH1G_HUMAN Usher syndrome type-1G protein OS... | 95 | 3.7 | 34.7 | 33 | 47 | GO:0015629; C:actin cytoskeleton; ISS:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0050957; P:equilibrioception; IMP:HGNC.::GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.::GO:0007605; P:sensory perception of sound; IMP:HGNC. | 239 | Q9Y2G4 | 727 | ANKR6_HUMAN Ankyrin repeat domain-containing ... | 77 | 3.9 | 35 | 31 | 45 | | | | | | | | | | | | | | | | | | | | | | 240 | Q5R6D7 | 288 | ASB8_PONAB Ankyrin repeat and SOCS box protei... | 138 | 3.9 | 34.3 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 241 | Q91974 | 318 | IKBA_CHICK NF-kappa-B inhibitor alpha OS=Gall... | 66 | 3.9 | 34.7 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048145; P:regulation of fibroblast proliferation; NAS:UniProtKB.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome. |
