| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
481 | Q5U4T3 | 771 | RHG26_XENLA Rho GTPase-activating protein 26 ... | 56 | 4.1 | 33.5 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 482 | Q86WN1 | 690 | FCSD1_HUMAN FCH and double SH3 domains protei... | 65 | 4.1 | 33.5 | 28 | 48 | | | | | | | | | | | | | | | | | | | | | | 483 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 54 | 4.2 | 33.9 | 24 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 484 | O77774 | 392 | NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos... | 54 | 4.2 | 33.5 | 30 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB. | 485 | Q6ZQ82 | 814 | RHG26_MOUSE Rho GTPase-activating protein 26 ... | 62 | 4.2 | 33.5 | 34 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 486 | A7KAX9 | 2087 | RHG32_HUMAN Rho GTPase-activating protein 32 ... | 65 | 4.4 | 33.9 | 28 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 487 | Q6DCZ7 | 543 | FBP1L_XENLA Formin-binding protein 1-like OS=... | 54 | 4.4 | 33.5 | 30 | 56 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 488 | Q9UNA1 | 814 | RHG26_HUMAN Rho GTPase-activating protein 26 ... | 62 | 4.6 | 33.5 | 34 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 489 | P08630 | 786 | BTKL_DROME Tyrosine-protein kinase Btk29A OS=... | 54 | 4.7 | 33.5 | 30 | 52 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0045172; C:germline ring canal; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:FlyBase.::GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007619; P:courtship behavior; NAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0007301; P:female germline ring canal formation; IDA:UniProtKB.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007485; P:imaginal disc-derived male genitalia development; IMP:UniProtKB.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030833; P:regulation of actin filament polymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0046960; P:sensitization; IMP:FlyBase. | 490 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 39 | 5 | 33.1 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 491 | Q6PFY1 | 688 | FCSD1_MOUSE FCH and double SH3 domains protei... | 55 | 5.5 | 33.1 | 29 | 53 | | | | | | | | | | | | | | | | | | | | | | 492 | P10447 | 439 | ABL_FSVHY Tyrosine-protein kinase transformin... | 51 | 5.6 | 33.1 | 29 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 493 | Q9BYB0 | 1741 | SHAN3_HUMAN SH3 and multiple ankyrin repeat d... | 64 | 5.9 | 33.1 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; ISS:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0097117; P:guanylate kinase-associated protein clustering; ISS:BHF-UCL.::GO:0007612; P:learning; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; ISS:BHF-UCL.::GO:0007613; P:memory; ISS:BHF-UCL.::GO:0097114; P:N-methyl-D-aspartate receptor clustering; ISS:BHF-UCL.::GO:0045794; P:negative regulation of cell volume; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; ISS:BHF-UCL.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:2000822; P:regulation of behavioral fear response; ISS:BHF-UCL.::GO:1900271; P:regulation of long-term synaptic potentiation; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0021773; P:striatal medium spiny neuron differentiation; ISS:BHF-UCL.::GO:0071625; P:vocalization behavior; ISS:BHF-UCL. | 494 | Q5ZMW5 | 760 | RHG26_CHICK Rho GTPase-activating protein 26 ... | 56 | 6.1 | 33.1 | 34 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 495 | Q19951 | 330 | PEX13_CAEEL Probable peroxisomal membrane pro... | 59 | 6.3 | 32.7 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 496 | Q6PG29 | 341 | SKAP2_DANRE Src kinase-associated phosphoprot... | 39 | 6.7 | 32.7 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 497 | P16885 | 1265 | PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 52 | 6.7 | 33.1 | 37 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB. | 498 | B6QEE0 | 282 | SHO1_PENMQ High osmolarity signaling protein ... | 59 | 7.3 | 32.3 | 31 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 499 | Q4WUG9 | 288 | SHO1_ASPFU High osmolarity signaling protein ... | 155 | 8.2 | 32.3 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 500 | B0Y3Z4 | 288 | SHO1_ASPFC High osmolarity signaling protein ... | 155 | 8.2 | 32.3 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 501 | P38822 | 633 | BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere... | 65 | 8.3 | 32.7 | 28 | 57 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD. | 502 | Q92BV2 | 603 | MUTL_LISIN DNA mismatch repair protein mutL O... | 64 | 9.8 | 32.3 | 34 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006298; P:mismatch repair; IEA:InterPro. |
