rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | P41241 | 450 | CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ... | 57 | 0.006 | 42.7 | 39 | 56 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC. | 302 | P41240 | 450 | CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo... | 57 | 0.006 | 42.4 | 39 | 56 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005886; C:plasma membrane; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 303 | P32577 | 450 | CSK_RAT Tyrosine-protein kinase CSK OS=Rattus... | 57 | 0.006 | 42.4 | 39 | 56 | GO:0045121; C:membrane raft; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0034332; P:adherens junction organization; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IDA:RGD.::GO:0045779; P:negative regulation of bone resorption; IDA:RGD.::GO:0008285; P:negative regulation of cell proliferation; IDA:RGD.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IDA:RGD.::GO:0033673; P:negative regulation of kinase activity; IDA:RGD.::GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IDA:RGD.::GO:0050765; P:negative regulation of phagocytosis; IDA:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0060368; P:regulation of Fc receptor mediated stimulatory signaling pathway; IDA:RGD. | 304 | Q0VBZ0 | 450 | CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ... | 57 | 0.006 | 42.4 | 39 | 56 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 305 | P14234 | 517 | FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus ... | 84 | 0.007 | 42.4 | 31 | 51 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:UniProtKB. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IDA:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; TAS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0045088; P:regulation of innate immune response; IMP:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB. | 306 | A6H7G2 | 423 | DBNL_BOVIN Drebrin-like protein OS=Bos taurus... | 99 | 0.007 | 42.4 | 25 | 56 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 307 | P42683 | 508 | LCK_CHICK Proto-oncogene tyrosine-protein kin... | 68 | 0.008 | 42.4 | 29 | 54 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 308 | O14302 | 886 | CYK3_SCHPO cytokinesis protein 3 OS=Schizosac... | 55 | 0.008 | 42.4 | 40 | 60 | GO:0005826; C:actomyosin contractile ring; NAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; NAS:PomBase. | 309 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 144 | 0.008 | 41.6 | 30 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 310 | E7RAI2 | 282 | SHO1_PICAD High osmolarity signaling protein ... | 86 | 0.008 | 41.6 | 33 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 311 | P00527 | 528 | YES_AVISY Tyrosine-protein kinase transformin... | 64 | 0.009 | 42 | 33 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 312 | A5GFW5 | 784 | CASS4_PIG Cas scaffolding protein family memb... | 59 | 0.01 | 42 | 29 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 313 | Q8QFX1 | 1325 | RIMB2_CHICK RIMS-binding protein 2 OS=Gallus ... | 171 | 0.01 | 42.4 | 24 | 42 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 314 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 56 | 0.068 | 39.7 | 38 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 315 | Q08EC4 | 804 | CASS4_MOUSE Cas scaffolding protein family me... | 56 | 0.011 | 42 | 30 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 316 | Q6TGW5 | 214 | OSTF1_DANRE Osteoclast-stimulating factor 1 O... | 50 | 0.012 | 40.8 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 317 | Q6P6U0 | 517 | FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus... | 61 | 0.012 | 41.6 | 36 | 57 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB. | 318 | Q5U2Y3 | 576 | MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt... | 81 | 0.012 | 41.6 | 32 | 48 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 319 | Q8BYZ1 | 367 | ABI3_MOUSE ABI gene family member 3 OS=Mus mu... | 54 | 0.013 | 41.2 | 31 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 320 | P13406 | 537 | FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno... | 71 | 0.015 | 41.2 | 34 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 321 | Q28923 | 539 | YES_CANFA Tyrosine-protein kinase Yes OS=Cani... | 60 | 0.015 | 41.2 | 37 | 57 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 322 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 72 | 0.015 | 41.2 | 36 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 323 | O15034 | 1052 | RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sa... | 63 | 0.016 | 41.6 | 30 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 324 | Q62662 | 506 | FRK_RAT Tyrosine-protein kinase FRK OS=Rattus... | 97 | 0.016 | 41.2 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD. | 325 | Q8WUF5 | 828 | IASPP_HUMAN RelA-associated inhibitor OS=Homo... | 58 | 0.017 | 41.2 | 31 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 326 | Q9QY17 | 488 | PACN2_RAT Protein kinase C and casein kinase ... | 58 | 0.017 | 41.2 | 33 | 62 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 327 | Q9WVE8 | 486 | PACN2_MOUSE Protein kinase C and casein kinas... | 58 | 0.018 | 41.2 | 33 | 62 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI. | 328 | A8PWF6 | 1322 | MYO1_MALGO Myosin-1 OS=(Dandruff-associated f... | 56 | 0.019 | 41.2 | 29 | 59 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 329 | Q62418 | 436 | DBNL_MOUSE Drebrin-like protein OS=Mus muscul... | 59 | 0.021 | 40.8 | 32 | 64 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; IDA:MGI. | 330 | E7A253 | 343 | SHO1_SPORE High osmolarity signaling protein ... | 57 | 0.021 | 40.4 | 35 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 331 | Q9JHL4 | 436 | DBNL_RAT Drebrin-like protein OS=Rattus norve... | 59 | 0.021 | 40.8 | 32 | 64 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB. |