| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P50545 | 524 | HCK_RAT Tyrosine-protein kinase HCK OS=Rattus... | 54 | 0.0002 | 47.4 | 35 | 61 | GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB. | 182 | Q9Z0W5 | 441 | PACN1_RAT Protein kinase C and casein kinase ... | 66 | 0.0002 | 47.4 | 33 | 58 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IDA:RGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 183 | Q61644 | 441 | PACN1_MOUSE Protein kinase C and casein kinas... | 66 | 0.0002 | 47.4 | 33 | 58 | GO:0030137; C:COPI-coated vesicle; IDA:MGI. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI. | 184 | Q61140 | 874 | BCAR1_MOUSE Breast cancer anti-estrogen resis... | 58 | 0.0002 | 47.8 | 36 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB. | 185 | Q99963 | 347 | SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu... | 53 | 0.0002 | 47 | 34 | 62 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 186 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 58 | 0.0002 | 47.8 | 34 | 57 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 187 | Q13813 | 2472 | SPTA2_HUMAN Spectrin alpha chain, brain OS=Ho... | 63 | 0.0002 | 47.8 | 30 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0008091; C:spectrin; TAS:ProtInc. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome. | 188 | P07751 | 2477 | SPTA2_CHICK Spectrin alpha chain, brain OS=Ga... | 63 | 0.0002 | 47.8 | 30 | 56 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 189 | P13395 | 2415 | SPTCA_DROME Spectrin alpha chain OS=Drosophil... | 67 | 0.0002 | 47.8 | 30 | 55 | GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0045170; C:spectrosome; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IDA:FlyBase.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:FlyBase. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0016199; P:axon midline choice point recognition; IGI:FlyBase.::GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0045478; P:fusome organization; TAS:FlyBase.::GO:0030727; P:germarium-derived female germ-line cyst formation; IMP:FlyBase.::GO:0007294; P:germarium-derived oocyte fate determination; IMP:FlyBase.::GO:0042062; P:long-term strengthening of neuromuscular junction; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IDA:FlyBase.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0007308; P:oocyte construction; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0007009; P:plasma membrane organization; TAS:FlyBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0030721; P:spectrosome organization; TAS:FlyBase. | 190 | Q9V9J3 | 517 | SRC42_DROME Tyrosine-protein kinase Src42A OS... | 65 | 0.0002 | 47.4 | 38 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 191 | Q9R0C8 | 847 | VAV3_MOUSE Guanine nucleotide exchange factor... | 53 | 0.0002 | 47.4 | 45 | 62 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.::GO:0006906; P:vesicle fusion; IGI:MGI. | 192 | Q9ES28 | 862 | ARHG7_MOUSE Rho guanine nucleotide exchange f... | 62 | 0.0002 | 47.4 | 37 | 55 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 193 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 52 | 0.0002 | 47 | 38 | 58 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 194 | P15891 | 592 | ABP1_YEAST Actin-binding protein OS=Saccharom... | 56 | 0.0002 | 47 | 38 | 63 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD. | 195 | Q62417 | 1290 | SRBS1_MOUSE Sorbin and SH3 domain-containing ... | 55 | 0.001 | 45.1 | 36 | 58 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.::GO:0015758; P:glucose transport; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0043149; P:stress fiber assembly; IDA:UniProtKB. | 196 | Q15080 | 339 | NCF4_HUMAN Neutrophil cytosol factor 4 OS=Hom... | 56 | 0.0002 | 46.6 | 45 | 59 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0043020; C:NADPH oxidase complex; IDA:UniProtKB.::GO:0032010; C:phagolysosome; TAS:Reactome. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006955; P:immune response; TAS:UniProtKB.::GO:0055114; P:oxidation-reduction process; TAS:UniProtKB. | 197 | O55043 | 646 | ARHG7_RAT Rho guanine nucleotide exchange fac... | 50 | 0.0002 | 47 | 42 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD. | 198 | Q62421 | 347 | SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo... | 53 | 0.0002 | 46.6 | 34 | 62 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 199 | P51451 | 505 | BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo... | 54 | 0.0003 | 47 | 41 | 59 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB. | 200 | P42522 | 1182 | MYOC_DICDI Myosin IC heavy chain OS=Dictyoste... | 58 | 0.0003 | 47.4 | 31 | 69 | GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IMP:dictyBase. | 201 | P56945 | 870 | BCAR1_HUMAN Breast cancer anti-estrogen resis... | 62 | 0.0003 | 47 | 34 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; IMP:BHF-UCL.::GO:0051301; P:cell division; NAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.::GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 202 | O35180 | 347 | SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ... | 53 | 0.0003 | 46.6 | 34 | 62 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 203 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 71 | 0.0003 | 47.4 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 204 | P17713 | 509 | STK_HYDVU Tyrosine-protein kinase STK OS=Hydr... | 92 | 0.0003 | 46.6 | 32 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 205 | Q2KJB5 | 505 | NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G... | 70 | 0.0003 | 46.6 | 34 | 54 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 206 | Q13625 | 1128 | ASPP2_HUMAN Apoptosis-stimulating of p53 prot... | 51 | 0.0003 | 47 | 31 | 61 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 207 | Q9BX66 | 1292 | SRBS1_HUMAN Sorbin and SH3 domain-containing ... | 55 | 0.0008 | 45.8 | 36 | 58 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.::GO:0005915; C:zonula adherens; TAS:ProtInc. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:BHF-UCL.::GO:0043149; P:stress fiber assembly; ISS:UniProtKB. | 208 | P27870 | 845 | VAV_MOUSE Proto-oncogene vav OS=Mus musculus ... | 65 | 0.0003 | 47 | 37 | 54 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI. | | | | | | | | | | GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI. | 209 | P08103 | 524 | HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus ... | 54 | 0.0004 | 46.6 | 33 | 61 | GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; IGI:MGI.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB. | 210 | O35964 | 368 | SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ... | 54 | 0.0004 | 46.2 | 33 | 67 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 211 | Q62419 | 368 | SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo... | 54 | 0.0004 | 45.8 | 33 | 67 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |
