| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P08096 | 1485 | TOP2_SCHPO DNA topoisomerase 2 OS=Schizosacch... | 1391 | 0 | 1323 | 48 | 65 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); ISS:RefGenome.::GO:0000795; C:synaptonemal complex; ISS:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IC:PomBase.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:PomBase. | | | | | | | | | | GO:0006325; P:chromatin organization; IGI:PomBase.::GO:0006271; P:DNA strand elongation involved in DNA replication; ISS:PomBase.::GO:0006265; P:DNA topological change; IDA:PomBase.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; ISS:RefGenome.::GO:0007076; P:mitotic chromosome condensation; IMP:PomBase.::GO:0006312; P:mitotic recombination; ISS:RefGenome.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:PomBase.::GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IGI:PomBase. | 2 | Q9Y8G8 | 1587 | TOP2_PENCH DNA topoisomerase 2 OS=Penicillium... | 1214 | 0 | 1323 | 54 | 71 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 3 | Q01879 | 1400 | TOP2_PICGU DNA topoisomerase 2 OS=1539 / NBRC... | 1201 | 0 | 1298 | 54 | 71 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 4 | O93794 | 1406 | TOP2_CANGA DNA topoisomerase 2 OS=NRRL Y-65) ... | 1171 | 0 | 1262 | 53 | 69 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 5 | P87078 | 1461 | TOP2_CANAX DNA topoisomerase 2 OS=Candida alb... | 1212 | 0 | 1260 | 52 | 68 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 6 | P06786 | 1428 | TOP2_YEAST DNA topoisomerase 2 OS=Saccharomyc... | 1176 | 0 | 1238 | 53 | 69 | GO:0097047; C:DNA replication termination region; IPI:SGD.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000795; C:synaptonemal complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:SGD. | | | | | | | | | | GO:0006333; P:chromatin assembly or disassembly; IMP:SGD.::GO:0031055; P:chromatin remodeling at centromere; IMP:SGD.::GO:0006271; P:DNA strand elongation involved in DNA replication; IMP:SGD.::GO:0006265; P:DNA topological change; IDA:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IMP:SGD.::GO:0000019; P:regulation of mitotic recombination; IMP:SGD.::GO:0097046; P:replication fork progression beyond termination site; IMP:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 7 | O24308 | 1462 | TOP2_PEA DNA topoisomerase 2 OS=Pisum sativum... | 1151 | 0 | 1186 | 52 | 70 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 8 | O42130 | 1553 | TOP2A_CHICK DNA topoisomerase 2-alpha OS=Gall... | 1160 | 0 | 1177 | 51 | 69 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); ISS:AgBase.::GO:0005654; C:nucleoplasm; ISS:AgBase.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:AgBase.::GO:0008144; F:drug binding; ISS:AgBase.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome. | | | | | | | | | | GO:0030263; P:apoptotic chromosome condensation; ISS:AgBase.::GO:0006266; P:DNA ligation; ISS:AgBase.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; ISS:AgBase.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; ISS:AgBase.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 9 | Q01320 | 1528 | TOP2A_MOUSE DNA topoisomerase 2-alpha OS=Mus ... | 1163 | 0 | 1173 | 51 | 68 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005730; C:nucleolus; IDA:MGI.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:MGI.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome. | | | | | | | | | | GO:0030261; P:chromosome condensation; IMP:MGI.::GO:0006265; P:DNA topological change; IDA:MGI.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0040016; P:embryonic cleavage; IMP:MGI.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 10 | P41515 | 1526 | TOP2A_CRIGR DNA topoisomerase 2-alpha OS=Cric... | 1163 | 0 | 1173 | 51 | 68 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 11 | O16140 | 1547 | TOP2_BOMMO DNA topoisomerase 2 OS=Bombyx mori... | 1276 | 0 | 1173 | 48 | 65 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 12 | P11388 | 1531 | TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo... | 1165 | 0 | 1168 | 51 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:UniProtKB.::GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IMP:UniProtKB. | | | | | | | | | | GO:0030263; P:apoptotic chromosome condensation; IDA:UniProtKB.::GO:0006266; P:DNA ligation; IDA:UniProtKB.::GO:0006281; P:DNA repair; NAS:UniProtKB.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0045870; P:positive regulation of retroviral genome replication; IMP:UniProtKB.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 13 | P30182 | 1473 | TOP2_ARATH DNA topoisomerase 2 OS=Arabidopsis... | 1189 | 0 | 1165 | 50 | 69 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 14 | O46374 | 1533 | TOP2A_PIG DNA topoisomerase 2-alpha OS=Sus sc... | 1173 | 0 | 1160 | 50 | 68 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 15 | P41516 | 1526 | TOP2A_RAT DNA topoisomerase 2-alpha OS=Rattus... | 1166 | 0 | 1155 | 50 | 68 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IDA:RGD.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; IDA:RGD.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:RGD.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0043566; F:structure-specific DNA binding; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006265; P:DNA topological change; IDA:RGD.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0071107; P:response to parathyroid hormone stimulus; IEP:RGD.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 16 | Q02880 | 1626 | TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo ... | 1168 | 0 | 1151 | 50 | 67 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB. | | | | | | | | | | GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 17 | O42131 | 1627 | TOP2B_CHICK DNA topoisomerase 2-beta OS=Gallu... | 1207 | 0 | 1150 | 49 | 66 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome. | | | | | | | | | | GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 18 | Q64399 | 1612 | TOP2B_CRILO DNA topoisomerase 2-beta OS=hamst... | 246 | 3.3 | 36.2 | 22 | 36 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 19 | Q64511 | 1612 | TOP2B_MOUSE DNA topoisomerase 2-beta OS=Mus m... | 247 | 2 | 37 | 23 | 36 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:MGI.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 20 | P15348 | 1447 | TOP2_DROME DNA topoisomerase 2 OS=Drosophila ... | 1240 | 0 | 1144 | 48 | 65 | GO:0008623; C:chromatin accessibility complex; IDA:FlyBase.::GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005626; C:insoluble fraction; IDA:FlyBase.::GO:0005625; C:soluble fraction; IDA:FlyBase.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IDA:FlyBase.::GO:0000400; F:four-way junction DNA binding; IDA:FlyBase.::GO:0003729; F:mRNA binding; IDA:FlyBase.::GO:0000182; F:rDNA binding; IDA:FlyBase.::GO:0003696; F:satellite DNA binding; IDA:FlyBase. | | | | | | | | | | GO:0006342; P:chromatin silencing; IDA:FlyBase.::GO:0006265; P:DNA topological change; IDA:FlyBase.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0051310; P:metaphase plate congression; IDA:FlyBase.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0007076; P:mitotic chromosome condensation; IMP:FlyBase.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome. | 21 | Q23670 | 1520 | TOP2_CAEEL Probable DNA topoisomerase 2 OS=Ca... | 1204 | 0 | 1133 | 48 | 67 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 22 | P41001 | 1398 | TOP2_PLAFK DNA topoisomerase 2 OS=Plasmodium ... | 1198 | 0 | 1084 | 48 | 65 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 23 | Q55BP5 | 1521 | TOP2_DICDI Probable DNA topoisomerase 2 OS=Di... | 1249 | 0 | 1059 | 46 | 64 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:dictyBase. | | | | | | | | | | GO:0006265; P:DNA topological change; ISS:dictyBase.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 24 | P90520 | 1284 | TOP2M_DICDI DNA topoisomerase 2, mitochondria... | 1210 | 0 | 948 | 43 | 62 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; ISS:dictyBase. | | | | | | | | | | GO:0006265; P:DNA topological change; IC:dictyBase.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 25 | P34534 | 1170 | TOP2M_CAEEL Putative DNA topoisomerase 2, mit... | 1161 | 0 | 797 | 40 | 59 | GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome. | | | | | | | | | | GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome. | 26 | Q5UQE6 | 1263 | TOP2_MIMIV DNA topoisomerase 2 OS=Acanthamoeb... | 228 | 1e-16 | 90.1 | 28 | 48 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 27 | P12531 | 1221 | TOP2_TRYBB DNA topoisomerase 2 OS=Trypanosoma... | 1153 | 0 | 622 | 35 | 52 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 28 | P30190 | 1232 | TOP2_TRYCR DNA topoisomerase 2 OS=Trypanosoma... | 1161 | 0 | 609 | 34 | 53 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 29 | Q9QSK1 | 1132 | TOP2_IIV6 DNA topoisomerase 2 OS=Invertebrate... | 1187 | 0 | 598 | 34 | 51 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 30 | O61078 | 1236 | TOP2_LEICH DNA topoisomerase 2 OS=Leishmania ... | 1165 | 0 | 592 | 33 | 52 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 31 | P27570 | 1239 | TOP2_CRIFA DNA topoisomerase 2 OS=Crithidia f... | 1172 | 0 | 589 | 33 | 52 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0020023; C:kinetoplast; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. |
