Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
197686
Length:
1341
Number of sequences:
10438
Description:
estExt_Genewise1Plus.C_11453
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61B4LXW1    614   SUR8_DROVI Leucine-rich repeat protein soc-2 ...853.5     35.8     28     48
62B4N9T4    641   SUR8_DROWI Leucine-rich repeat protein soc-2 ...885.9     35     28     47
63P49606    2493   CYAA_USTMA Adenylate cyclase OS=Ustilago mayd...1226.1     35     25     43
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
64Q9V780    849   LAP1_DROME Protein lap1 OS=Drosophila melanog...815.8     35     31     49GO:0005912; C:adherens junction; ISS:UniProtKB.
GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0015031; P:protein transport; ISS:UniProtKB.
65A6NIK2    292   LR10B_HUMAN Leucine-rich repeat-containing pr...1020.045     41.2     31     45
66Q3KQF4    345   LRC69_XENLA Leucine-rich repeat-containing pr...1093     35.4     30     46
67Q66HD6    256   LRC18_RAT Leucine-rich repeat-containing prot...1390.21     38.9     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
68B3P3E8    644   SUR8_DROER Leucine-rich repeat protein soc-2 ...1223.1     35.8     29     41
69B4QVR7    680   SUR8_DROSI Leucine-rich repeat protein soc-2 ...882.7     36.2     28     47
70O75962    3097   TRIO_HUMAN Triple functional domain protein O...1470.35     39.3     27     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
71B4PU77    645   SUR8_DROYA Leucine-rich repeat protein soc-2 ...1223.1     35.8     29     41
72B5DX45    629   SUR8_DROPS Leucine-rich repeat protein soc-2 ...1223.1     35.8     29     40
73A6QLV3    582   SHOC2_BOVIN Leucine-rich repeat protein SHOC-...1315.1     35     26     48GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB.
GO:0019903; F:protein phosphatase binding; ISS:UniProtKB.
GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.
74Q5RAV5    582   SHOC2_PONAB Leucine-rich repeat protein SHOC-...1315.3     35     26     48GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB.
GO:0019903; F:protein phosphatase binding; ISS:UniProtKB.
GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.
75Q9UQ13    582   SHOC2_HUMAN Leucine-rich repeat protein SHOC-...1315.3     35     26     48GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; IDA:UniProtKB.
GO:0019903; F:protein phosphatase binding; IDA:UniProtKB.::GO:0019888; F:protein phosphatase regulator activity; TAS:UniProtKB.
GO:0008543; P:fibroblast growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; IMP:UniProtKB.::GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
76B4IBI9    683   SUR8_DROSE Leucine-rich repeat protein soc-2 ...882.6     36.2     28     47
77O60346    1717   PHLP1_HUMAN PH domain leucine-rich repeat-con...1004.1     35.4     31     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
78Q5F4C4    529   SHOC2_CHICK Leucine-rich repeat protein SHOC-...1210.16     40     27     44GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000164; C:protein phosphatase type 1 complex; ISS:UniProtKB.
GO:0019903; F:protein phosphatase binding; ISS:UniProtKB.
GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.
79Q0KL02    3102   TRIO_MOUSE Triple functional domain protein O...1470.28     39.7     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
80Q96NW7    1537   LRRC7_HUMAN Leucine-rich repeat-containing pr...1000.036     42.4     28     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
81B3LWU3    641   SUR8_DROAN Leucine-rich repeat protein soc-2 ...942.8     35.8     29     46
82Q1LUA6    3028   TRIO_DANRE Triple functional domain protein O...1470.26     39.7     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
83Q9CQ07    262   LRC18_MOUSE Leucine-rich repeat-containing pr...1390.08     40     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
84Q9Z0R4    1714   ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo...1660.000002     56.6     28     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
85Q15811    1721   ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu...2040.000002     56.6     26     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
86Q9Y4C4    1052   MFHA1_HUMAN Malignant fibrous histiocytoma-am...1110.017     43.5     32     50
87P27870    845   VAV_MOUSE Proto-oncogene vav OS=Mus musculus ...1650.000002     56.2     28     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI.
GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI.
88Q9H8V3    914   ECT2_HUMAN Protein ECT2 OS=Homo sapiens (Huma...3030.000002     56.2     21     41GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB.
GO:0005096; F:GTPase activator activity; IMP:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0033205; P:cell cycle cytokinesis; IMP:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0070830; P:tight junction assembly; IMP:UniProtKB.
89P15498    845   VAV_HUMAN Proto-oncogene vav OS=Homo sapiens ...1660.000002     55.8     28     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.
90Q9WTR8    1696   PHLP1_RAT PH domain leucine-rich repeat prote...1956.5     35     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.
91Q8N456    261   LRC18_HUMAN Leucine-rich repeat-containing pr...774.5     34.7     27     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
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