rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q9LP24 | 1120 | Y1571_ARATH Probable leucine-rich repeat rece... | 109 | 0.031 | 42.4 | 35 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 272 | Q80YS5 | 523 | LRC27_MOUSE Leucine-rich repeat-containing pr... | 111 | 0.036 | 42 | 30 | 45 | | | | | | | | | | | | | | | | | | | | | | 273 | Q64096 | 1149 | MCF2L_MOUSE Guanine nucleotide exchange facto... | 68 | 0.036 | 42.4 | 37 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 274 | Q09763 | 753 | GEF1_SCHPO Rho guanine nucleotide exchange fa... | 164 | 0.037 | 42 | 26 | 46 | GO:0030428; C:cell septum; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:PomBase. | | | | | | | | | | GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0032488; P:Cdc42 protein signal transduction; NAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.::GO:0032319; P:regulation of Rho GTPase activity; IDA:PomBase. | 275 | Q63406 | 1149 | MCF2L_RAT Guanine nucleotide exchange factor ... | 129 | 0.12 | 40.8 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 276 | Q24020 | 1256 | FLII_DROME Protein flightless-1 OS=Drosophila... | 105 | 5.9 | 35 | 31 | 46 | | | | | | | | | | | GO:0003779; F:actin binding; ISS:FlyBase. | | | | | | | | | | GO:0007527; P:adult somatic muscle development; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0010004; P:gastrulation involving germ band extension; IMP:FlyBase.::GO:0030239; P:myofibril assembly; IMP:FlyBase. | 277 | Q3UV48 | 300 | LRC30_MOUSE Leucine-rich repeat-containing pr... | 100 | 6 | 34.3 | 26 | 47 | | | | | | | | | | | | | | | | | | | | | | 278 | C0LGP4 | 1010 | Y3475_ARATH Probable LRR receptor-like serine... | 136 | 0.039 | 42 | 29 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 279 | Q8IVF5 | 1701 | TIAM2_HUMAN T-lymphoma invasion and metastasi... | 80 | 1.7 | 37 | 34 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 280 | Q54XZ5 | 1248 | Y0138_DICDI Probable serine/threonine-protein... | 80 | 0.19 | 40 | 36 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 281 | A0N0X6 | 716 | LRRN1_BOVIN Leucine-rich repeat neuronal prot... | 96 | 0.049 | 41.6 | 33 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 282 | Q9LHF1 | 494 | LRX4_ARATH Leucine-rich repeat extensin-like ... | 102 | 0.051 | 41.6 | 27 | 50 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW. | 283 | O94898 | 1065 | LRIG2_HUMAN Leucine-rich repeats and immunogl... | 124 | 0.053 | 41.6 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 284 | Q3UHC2 | 2014 | LRRK1_MOUSE Leucine-rich repeat serine/threon... | 105 | 2 | 36.6 | 30 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 285 | Q6XHA7 | 3365 | ROCO9_DICDI Probable serine/threonine-protein... | 104 | 2.5 | 36.2 | 24 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0016791; F:phosphatase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 286 | Q13045 | 1269 | FLII_HUMAN Protein flightless-1 homolog OS=Ho... | 82 | 6.4 | 35 | 30 | 51 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 287 | Q9C0I9 | 530 | LRC27_HUMAN Leucine-rich repeat-containing pr... | 110 | 0.063 | 41.2 | 30 | 48 | | | | | | | | | | | | | | | | | | | | | | 288 | Q52KR2 | 1054 | LRIG2_MOUSE Leucine-rich repeats and immunogl... | 124 | 0.065 | 41.6 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 289 | Q9JJ28 | 1271 | FLII_MOUSE Protein flightless-1 homolog OS=Mu... | 82 | 2.8 | 36.2 | 30 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:MGI.::GO:0051014; P:actin filament severing; TAS:MGI.::GO:0007275; P:multicellular organismal development; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 290 | Q8R4H2 | 1543 | ARHGC_MOUSE Rho guanine nucleotide exchange f... | 138 | 0.066 | 41.6 | 24 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 291 | Q6AXU9 | 557 | CNOT6_RAT CCR4-NOT transcription complex subu... | 82 | 0.19 | 39.7 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 292 | Q8K3P5 | 557 | CNOT6_MOUSE CCR4-NOT transcription complex su... | 82 | 0.19 | 39.7 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 293 | Q5DU41 | 791 | LRC8B_MOUSE Leucine-rich repeat-containing pr... | 88 | 4.9 | 35 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 294 | A1IGU4 | 676 | ARH37_MOUSE Rho guanine nucleotide exchange f... | 305 | 0.068 | 41.2 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 295 | Q5BJ41 | 552 | CNOT6_XENLA CCR4-NOT transcription complex su... | 82 | 0.2 | 39.7 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 296 | Q5R482 | 708 | LRRN3_PONAB Leucine-rich repeat neuronal prot... | 81 | 0.073 | 41.2 | 35 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 297 | Q9SN46 | 857 | LRX5_ARATH Leucine-rich repeat extensin-like ... | 102 | 0.077 | 41.2 | 26 | 47 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW. | 298 | Q32Q07 | 716 | LRRN1_RAT Leucine-rich repeat neuronal protei... | 96 | 0.079 | 41.2 | 33 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 299 | Q9H3W5 | 708 | LRRN3_HUMAN Leucine-rich repeat neuronal prot... | 81 | 0.079 | 41.2 | 35 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 300 | P51862 | 1356 | ROM2_YEAST RHO1 GDP-GTP exchange protein 2 OS... | 125 | 0.081 | 41.2 | 27 | 44 | GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IGI:SGD. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; IDA:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0043951; P:negative regulation of cAMP-mediated signaling; IMP:SGD.::GO:0045807; P:positive regulation of endocytosis; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 301 | Q6ZPF3 | 1715 | TIAM2_MOUSE T-lymphoma invasion and metastasi... | 80 | 2 | 36.6 | 34 | 54 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |