rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q86YR7 | 1114 | MF2L2_HUMAN Probable guanine nucleotide excha... | 97 | 0.0002 | 50.1 | 32 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 152 | Q24K06 | 278 | LRC10_BOVIN Leucine-rich repeat-containing pr... | 115 | 0.015 | 42.7 | 30 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 153 | Q5BKY1 | 277 | LRC10_HUMAN Leucine-rich repeat-containing pr... | 100 | 0.009 | 43.1 | 35 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 154 | A8JAM0 | 1159 | CC135_CHLRE Coiled-coil domain-containing pro... | 101 | 0.65 | 38.1 | 28 | 47 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001539; P:ciliary or flagellar motility; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 155 | Q6DHL5 | 238 | LRC57_DANRE Leucine-rich repeat-containing pr... | 108 | 0.002 | 45.1 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 156 | A2BHJ4 | 559 | CNO6L_DANRE CCR4-NOT transcription complex su... | 91 | 0.0002 | 49.3 | 35 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. | 157 | Q92888 | 912 | ARHG1_HUMAN Rho guanine nucleotide exchange f... | 293 | 0.0002 | 49.7 | 22 | 40 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 158 | Q9D1G5 | 239 | LRC57_MOUSE Leucine-rich repeat-containing pr... | 109 | 0.0002 | 48.1 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 159 | Q9Y2L9 | 728 | LRCH1_HUMAN Leucine-rich repeat and calponin ... | 91 | 0.032 | 42.4 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 160 | Q3ZC49 | 334 | LRC39_BOVIN Leucine-rich repeat-containing pr... | 139 | 0.028 | 42 | 27 | 48 | | | | | | | | | | | | | | | | | | | | | | 161 | A6NM36 | 301 | LRC30_HUMAN Leucine-rich repeat-containing pr... | 148 | 0.036 | 41.6 | 26 | 39 | | | | | | | | | | | | | | | | | | | | | | 162 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 281 | 0.0002 | 49.7 | 22 | 39 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 163 | Q4R6F0 | 863 | LRRD1_MACFA Leucine-rich repeat and death dom... | 157 | 1.4 | 37 | 27 | 46 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 164 | Q4V8G0 | 607 | LRC63_RAT Leucine-rich repeat-containing prot... | 88 | 0.023 | 42.7 | 33 | 48 | | | | | | | | | | | | | | | | | | | | | | 165 | Q7SXW3 | 601 | LRC40_DANRE Leucine-rich repeat-containing pr... | 105 | 3.3 | 35.8 | 30 | 45 | | | | | | | | | | | | | | | | | | | | | | 166 | Q9N0A8 | 526 | ARHG3_MACFA Rho guanine nucleotide exchange f... | 134 | 0.0003 | 48.9 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 167 | Q4H4B6 | 1724 | SCRIB_DANRE Protein scribble homolog OS=Danio... | 127 | 9.6 | 34.3 | 27 | 39 | GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:ZFIN. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060561; P:apoptotic process involved in morphogenesis; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0035089; P:establishment of apical/basal cell polarity; ISS:UniProtKB.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:ZFIN.::GO:0045930; P:negative regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0001764; P:neuron migration; IMP:ZFIN.::GO:0050918; P:positive chemotaxis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0014021; P:secondary neural tube formation; IMP:ZFIN. | 168 | Q5R6F2 | 526 | ARHG3_PONAB Rho guanine nucleotide exchange f... | 134 | 0.0003 | 48.5 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 169 | Q9NR81 | 526 | ARHG3_HUMAN Rho guanine nucleotide exchange f... | 134 | 0.0003 | 48.5 | 31 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 170 | A6H6A4 | 596 | LRIQ4_MOUSE Leucine-rich repeat and IQ domain... | 85 | 1.9 | 36.6 | 31 | 49 | | | | | | | | | | | | | | | | | | | | | | 171 | P62046 | 709 | LRCH1_MOUSE Leucine-rich repeat and calponin ... | 91 | 0.026 | 42.7 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 172 | Q96II8 | 777 | LRCH3_HUMAN Leucine-rich repeat and calponin ... | 80 | 3.4 | 35.8 | 29 | 50 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 173 | Q91X46 | 524 | ARHG3_MOUSE Rho guanine nucleotide exchange f... | 134 | 0.0003 | 48.5 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 174 | Q01513 | 2145 | CYAA_PODAS Adenylate cyclase OS=Podospora ans... | 115 | 2.6 | 36.2 | 25 | 43 | | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 175 | Q3V1N1 | 1048 | MFHA1_MOUSE Malignant fibrous histiocytoma-am... | 111 | 0.05 | 42 | 32 | 50 | | | | | | | | | | | | | | | | | | | | | | 176 | A1L390 | 1219 | PKHG3_HUMAN Pleckstrin homology domain-contai... | 139 | 0.002 | 46.2 | 25 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 177 | P08678 | 2026 | CYAA_YEAST Adenylate cyclase OS=Saccharomyces... | 121 | 0.9 | 37.7 | 31 | 48 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 178 | Q01730 | 277 | RSU1_MOUSE Ras suppressor protein 1 OS=Mus mu... | 123 | 0.3 | 38.5 | 28 | 46 | | | | | | | | | | | | | | | | | | | | | | 179 | Q8N9N7 | 239 | LRC57_HUMAN Leucine-rich repeat-containing pr... | 109 | 0.0005 | 47 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 180 | P40197 | 560 | GPV_HUMAN Platelet glycoprotein V OS=Homo sap... | 59 | 3.8 | 35.4 | 37 | 56 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | | | | | | | | | | | GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome. | 181 | P23466 | 1839 | CYAA_LACKL Adenylate cyclase OS=Lachancea klu... | 103 | 1.4 | 37.4 | 28 | 50 | | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. |