rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | C7GNA4 | 687 | YEL1_YEAS2 Guanine-nucleotide exchange factor... | 48 | 0.35 | 38.9 | 35 | 63 | GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 62 | Q9H254 | 2564 | SPTN4_HUMAN Spectrin beta chain, brain 3 OS=H... | 117 | 0.66 | 38.1 | 26 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008091; C:spectrin; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; TAS:UniProtKB.::GO:0030506; F:ankyrin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB. | 63 | Q60610 | 1591 | TIAM1_MOUSE T-lymphoma invasion and metastasi... | 139 | 0.83 | 37.7 | 27 | 42 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0031547; P:brain-derived neurotrophic factor receptor signaling pathway; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB. | 64 | Q13009 | 1591 | TIAM1_HUMAN T-lymphoma invasion and metastasi... | 139 | 0.9 | 37.7 | 27 | 40 | GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 65 | A2BID5 | 813 | MELT_DANRE Ventricular zone-expressed PH doma... | 104 | 1.1 | 37.4 | 28 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IMP:ZFIN.::GO:0042471; P:ear morphogenesis; IMP:ZFIN. | 66 | Q9QWN8 | 2388 | SPTN2_RAT Spectrin beta chain, brain 2 OS=Rat... | 120 | 1.3 | 37.4 | 22 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016363; C:nuclear matrix; TAS:UniProtKB.::GO:0008091; C:spectrin; TAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; TAS:UniProtKB.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; TAS:UniProtKB. | 67 | Q6ZPF3 | 1715 | TIAM2_MOUSE T-lymphoma invasion and metastasi... | 127 | 1.5 | 37 | 28 | 43 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 68 | Q9PR10 | 179 | ATPD_UREPA ATP synthase subunit delta OS=Urea... | 93 | 1.7 | 35.4 | 29 | 49 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW. | | | | | | | | | | GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro. | | | | | | | | | | GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. | 69 | B1AIC3 | 179 | ATPD_UREP2 ATP synthase subunit delta OS=Urea... | 93 | 1.7 | 35.4 | 29 | 49 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW. | | | | | | | | | | GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro. | | | | | | | | | | GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. | 70 | P34225 | 687 | YEL1_YEAST Guanine-nucleotide exchange factor... | 48 | 2.9 | 35.8 | 33 | 60 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 71 | C8Z3N7 | 687 | YEL1_YEAS8 Guanine-nucleotide exchange factor... | 48 | 2.9 | 35.8 | 33 | 60 | GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 72 | A6ZKN8 | 687 | YEL1_YEAS7 Guanine-nucleotide exchange factor... | 48 | 2.9 | 35.8 | 33 | 60 | GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 73 | O95294 | 804 | RASL1_HUMAN RasGAP-activating-like protein 1 ... | 151 | 3.2 | 35.8 | 26 | 42 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 74 | Q57673 | 206 | VATE_METJA V-type ATP synthase subunit E OS=J... | 107 | 4.5 | 34.3 | 29 | 50 | GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro. | | | | | | | | | | GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro. | | | | | | | | | | GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. | 75 | B5ZAW6 | 179 | ATPD_UREU1 ATP synthase subunit delta OS=Urea... | 92 | 4.9 | 33.9 | 28 | 49 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW. | | | | | | | | | | GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro. | | | | | | | | | | GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. |