rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | P28828 | 1452 | PTPRM_MOUSE Receptor-type tyrosine-protein ph... | 325 | 0.0000000000002 | 75.9 | 24 | 39 | GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB. | 92 | P54637 | 990 | PTP3_DICDI Tyrosine-protein phosphatase 3 OS=... | 355 | 0.0000000000003 | 74.7 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IMP:dictyBase.::GO:0034504; P:protein localization to nucleus; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IMP:dictyBase.::GO:0042501; P:serine phosphorylation of STAT protein; IMP:dictyBase. | 93 | Q8BUM3 | 359 | PTN7_MOUSE Tyrosine-protein phosphatase non-r... | 291 | 0.0000000000007 | 72.8 | 25 | 41 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI. | | | | | | | | | | | 94 | P49445 | 359 | PTN7_RAT Tyrosine-protein phosphatase non-rec... | 291 | 0.0000000000007 | 72.8 | 25 | 42 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 95 | Q92729 | 1446 | PTPRU_HUMAN Receptor-type tyrosine-protein ph... | 260 | 0.000000000003 | 72 | 26 | 42 | GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; NAS:UniProtKB. | 96 | P23469 | 700 | PTPRE_HUMAN Receptor-type tyrosine-protein ph... | 328 | 0.00000000002 | 68.9 | 24 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 97 | Q9H3S7 | 1636 | PTN23_HUMAN Tyrosine-protein phosphatase non-... | 249 | 0.00000000001 | 70.5 | 24 | 44 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; IMP:UniProtKB. | 98 | B3DK56 | 1444 | PTPRU_DANRE Receptor-type tyrosine-protein ph... | 364 | 0.77 | 35.8 | 21 | 37 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001757; P:somite specification; IMP:ZFIN. | 99 | Q6PB44 | 1692 | PTN23_MOUSE Tyrosine-protein phosphatase non-... | 249 | 0.00000000001 | 70.1 | 24 | 44 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB. | 100 | P18433 | 802 | PTPRA_HUMAN Receptor-type tyrosine-protein ph... | 319 | 0.0000000002 | 66.2 | 23 | 39 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 101 | Q03348 | 796 | PTPRA_RAT Receptor-type tyrosine-protein phos... | 314 | 0.000000002 | 63.2 | 23 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:RGD. | | | | | | | | | | GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IMP:RGD.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 102 | P49446 | 699 | PTPRE_MOUSE Receptor-type tyrosine-protein ph... | 363 | 0.0000000004 | 65.1 | 21 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI. | 103 | Q62132 | 656 | PTPRR_MOUSE Receptor-type tyrosine-protein ph... | 261 | 0.00000000004 | 68.2 | 28 | 43 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001701; P:in utero embryonic development; ISS:UniProtKB. | 104 | Q24708 | 764 | CSW_DROVI Tyrosine-protein phosphatase corksc... | 211 | 0.00000000005 | 68.2 | 29 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB. | 105 | B2GV87 | 699 | PTPRE_RAT Receptor-type tyrosine-protein phos... | 363 | 0.0000000003 | 65.1 | 21 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; NAS:RGD. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 106 | Q6YI48 | 1434 | PTPRU_CHICK Receptor-type tyrosine-protein ph... | 259 | 0.00000000006 | 67.8 | 26 | 42 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 107 | O08617 | 656 | PTPRR_RAT Receptor-type tyrosine-protein phos... | 262 | 0.0000000001 | 66.6 | 27 | 42 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD. | 108 | P18052 | 829 | PTPRA_MOUSE Receptor-type tyrosine-protein ph... | 383 | 0.000007 | 51.6 | 22 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 109 | Q15256 | 657 | PTPRR_HUMAN Receptor-type tyrosine-protein ph... | 261 | 0.0000000002 | 66.2 | 27 | 42 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0001701; P:in utero embryonic development; IEP:UniProtKB. | 110 | B1AUH1 | 1446 | PTPRU_MOUSE Receptor-type tyrosine-protein ph... | 260 | 0.0000000002 | 66.2 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034109; P:homotypic cell-cell adhesion; IDA:MGI. | 111 | O88902 | 1499 | PTN23_RAT Tyrosine-protein phosphatase non-re... | 249 | 0.0000000002 | 66.2 | 23 | 43 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB. | 112 | P34138 | 377 | PTP2_DICDI Tyrosine-protein phosphatase 2 OS=... | 241 | 0.0000000003 | 64.7 | 25 | 38 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:dictyBase. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase. | 113 | P29461 | 750 | PTP2_YEAST Tyrosine-protein phosphatase 2 OS=... | 365 | 0.0000000003 | 65.5 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0043937; P:regulation of sporulation; IGI:SGD. | 114 | P54829 | 565 | PTN5_HUMAN Tyrosine-protein phosphatase non-r... | 257 | 0.000000004 | 62 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB. | | | | | | | | | | GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB. | | | | | | | | | | | 115 | P54830 | 541 | PTN5_MOUSE Tyrosine-protein phosphatase non-r... | 258 | 0.00000008 | 57.8 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI. | | | | | | | | | | | 116 | Q8ISC9 | 555 | CSW_DROSI Tyrosine-protein phosphatase corksc... | 215 | 0.0000001 | 57.4 | 28 | 40 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB. | 117 | P29349 | 845 | CSW_DROME Tyrosine-protein phosphatase corksc... | 52 | 0.003 | 43.5 | 42 | 58 | GO:0005737; C:cytoplasm; NAS:UniProtKB. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; NAS:FlyBase. | | | | | | | | | | GO:0008069; P:dorsal/ventral axis specification, ovarian follicular epithelium; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0007498; P:mesoderm development; IMP:FlyBase.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0045314; P:regulation of compound eye photoreceptor development; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; TAS:FlyBase.::GO:0007362; P:terminal region determination; IMP:UniProtKB.::GO:0008293; P:torso signaling pathway; IGI:UniProtKB.::GO:0007418; P:ventral midline development; IMP:FlyBase. | 118 | P35234 | 369 | PTN5_RAT Tyrosine-protein phosphatase non-rec... | 260 | 0.0000001 | 56.2 | 25 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 119 | Q63475 | 1004 | PTPR2_RAT Receptor-type tyrosine-protein phos... | 317 | 0.000004 | 52.8 | 22 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034260; P:negative regulation of GTPase activity; IDA:RGD. | 120 | O02695 | 1013 | PTPR2_MACNE Receptor-type tyrosine-protein ph... | 317 | 0.00001 | 50.8 | 22 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 121 | P80560 | 1001 | PTPR2_MOUSE Receptor-type tyrosine-protein ph... | 317 | 0.00003 | 50.1 | 21 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | |