| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P43378 | 593 | PTN9_HUMAN Tyrosine-protein phosphatase non-r... | 325 | 2e-16 | 84.7 | 25 | 41 | GO:0044444; C:cytoplasmic part; IDA:UniProtKB. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 62 | P70289 | 1705 | PTPRV_MOUSE Receptor-type tyrosine-protein ph... | 253 | 2e-16 | 84.7 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 63 | P34137 | 522 | PTP1_DICDI Tyrosine-protein phosphatase 1 OS=... | 267 | 3e-16 | 84 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 64 | Q9IBD8 | 1216 | PTPRC_CYPCA Receptor-type tyrosine-protein ph... | 334 | 1.1 | 35 | 22 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro. | 65 | Q9Y2R2 | 807 | PTN22_HUMAN Tyrosine-protein phosphatase non-... | 327 | 3e-16 | 84 | 26 | 39 | GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0019900; F:kinase binding; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL. | | | | | | | | | | GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; ISS:BHF-UCL.::GO:0050855; P:regulation of B cell receptor signaling pathway; NAS:BHF-UCL.::GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; IDA:BHF-UCL.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL. | 66 | Q64512 | 2453 | PTN13_MOUSE Tyrosine-protein phosphatase non-... | 324 | 3e-16 | 84.3 | 25 | 41 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 67 | Q90687 | 593 | PTN11_CHICK Tyrosine-protein phosphatase non-... | 265 | 5e-16 | 83.2 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 68 | O35239 | 593 | PTN9_MOUSE Tyrosine-protein phosphatase non-r... | 324 | 5e-16 | 82.8 | 25 | 41 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 69 | P28192 | 1159 | PTP2_CAEEL Tyrosine-protein phosphatase 2 OS=... | 341 | 6e-16 | 83.2 | 26 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 70 | Q641Z2 | 593 | PTN9_RAT Tyrosine-protein phosphatase non-rec... | 324 | 6e-16 | 82.8 | 25 | 41 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 71 | P27574 | 550 | PYP1_SCHPO Tyrosine-protein phosphatase 1 OS=... | 325 | 0.000000000000001 | 81.6 | 25 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:PomBase.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase. | 72 | P41499 | 597 | PTN11_RAT Tyrosine-protein phosphatase non-re... | 265 | 0.000000000000002 | 80.9 | 28 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0043274; F:phospholipase binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB. | 73 | P25044 | 335 | PTP1_YEAST Tyrosine-protein phosphatase 1 OS=... | 325 | 0.000000000000003 | 79.7 | 26 | 41 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD. | 74 | P35235 | 597 | PTN11_MOUSE Tyrosine-protein phosphatase non-... | 265 | 0.000000000000003 | 80.9 | 28 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0051428; F:peptide hormone receptor binding; IPI:MGI.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0000077; P:DNA damage checkpoint; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0042445; P:hormone metabolic process; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0048609; P:multicellular organismal reproductive process; IMP:MGI.::GO:0051463; P:negative regulation of cortisol secretion; IMP:MGI.::GO:0060125; P:negative regulation of growth hormone secretion; IMP:MGI.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0046887; P:positive regulation of hormone secretion; IMP:MGI.::GO:0009967; P:positive regulation of signal transduction; IMP:MGI.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0046825; P:regulation of protein export from nucleus; IMP:MGI.::GO:0006641; P:triglyceride metabolic process; IMP:MGI. | 75 | Q06124 | 597 | PTN11_HUMAN Tyrosine-protein phosphatase non-... | 265 | 0.000000000000003 | 80.5 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 76 | Q62656 | 2316 | PTPRZ_RAT Receptor-type tyrosine-protein phos... | 254 | 0.007 | 42.4 | 24 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 77 | Q05209 | 780 | PTN12_HUMAN Tyrosine-protein phosphatase non-... | 327 | 0.000000000000005 | 80.1 | 25 | 39 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | | 78 | Q99952 | 460 | PTN18_HUMAN Tyrosine-protein phosphatase non-... | 274 | 0.000000000000009 | 79 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 79 | Q15262 | 1439 | PTPRK_HUMAN Receptor-type tyrosine-protein ph... | 325 | 0.00000000000001 | 79.7 | 26 | 41 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 80 | P35831 | 775 | PTN12_MOUSE Tyrosine-protein phosphatase non-... | 327 | 0.00000000000001 | 79.3 | 25 | 39 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 81 | P35822 | 1457 | PTPRK_MOUSE Receptor-type tyrosine-protein ph... | 329 | 0.00000000000002 | 78.6 | 26 | 41 | GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 82 | P16620 | 1462 | PTP69_DROME Tyrosine-protein phosphatase 69D ... | 73 | 0.56 | 36.2 | 30 | 52 | GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007415; P:defasciculation of motor neuron axon; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase. | 83 | Q99M80 | 1454 | PTPRT_MOUSE Receptor-type tyrosine-protein ph... | 321 | 0.014 | 41.2 | 23 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0051393; F:alpha-actinin binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0045296; F:cadherin binding; IPI:MGI.::GO:0070097; F:delta-catenin binding; IPI:MGI.::GO:0045295; F:gamma-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016790; F:thiolester hydrolase activity; IDA:MGI. | | | | | | | | | | | 84 | O14522 | 1441 | PTPRT_HUMAN Receptor-type tyrosine-protein ph... | 321 | 0.021 | 40.8 | 23 | 35 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0045294; F:alpha-catenin binding; IDA:UniProtKB.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045296; F:cadherin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB. | 85 | P29352 | 802 | PTN22_MOUSE Tyrosine-protein phosphatase non-... | 327 | 0.00000000000003 | 77.8 | 25 | 38 | GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI. | 86 | P35236 | 360 | PTN7_HUMAN Tyrosine-protein phosphatase non-r... | 291 | 0.00000000000004 | 76.6 | 27 | 41 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 87 | P23471 | 2315 | PTPRZ_HUMAN Receptor-type tyrosine-protein ph... | 262 | 0.006 | 42.4 | 24 | 39 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0008330; F:protein tyrosine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc. | 88 | Q64612 | 1711 | PTPRV_RAT Receptor-type tyrosine-protein phos... | 250 | 0.00000000000005 | 77.4 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046849; P:bone remodeling; IEP:RGD. | 89 | P28827 | 1452 | PTPRM_HUMAN Receptor-type tyrosine-protein ph... | 325 | 0.00000000000008 | 77 | 24 | 40 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB. | 90 | Q61152 | 453 | PTN18_MOUSE Tyrosine-protein phosphatase non-... | 272 | 0.0000000000002 | 75.1 | 26 | 41 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 91 | P28828 | 1452 | PTPRM_MOUSE Receptor-type tyrosine-protein ph... | 325 | 0.0000000000002 | 75.9 | 24 | 39 | GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB. |
