| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q15678 | 1187 | PTN14_HUMAN Tyrosine-protein phosphatase non-... | 368 | 1e-23 | 107 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0001946; P:lymphangiogenesis; IMP:UniProtKB. | 2 | B0V2N1 | 1907 | PTPRS_MOUSE Receptor-type tyrosine-protein ph... | 277 | 0.00000000000003 | 78.2 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI. | 3 | Q64605 | 1907 | PTPRS_RAT Receptor-type tyrosine-protein phos... | 277 | 0.00000000000003 | 78.2 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 4 | Q64455 | 1238 | PTPRJ_MOUSE Receptor-type tyrosine-protein ph... | 262 | 3e-22 | 102 | 29 | 45 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000272; P:negative regulation of receptor activity; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:UniProtKB.::GO:0010572; P:positive regulation of platelet activation; IMP:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:MGI. | 5 | Q64487 | 1912 | PTPRD_MOUSE Receptor-type tyrosine-protein ph... | 308 | 6e-17 | 86.7 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | P23468 | 1912 | PTPRD_HUMAN Receptor-type tyrosine-protein ph... | 308 | 5e-17 | 86.7 | 25 | 42 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 7 | Q9W6V5 | 1406 | PTPRJ_CHICK Receptor-type tyrosine-protein ph... | 268 | 3e-22 | 102 | 30 | 44 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB. | 8 | Q16827 | 1216 | PTPRO_HUMAN Receptor-type tyrosine-protein ph... | 261 | 4e-22 | 102 | 28 | 44 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0030424; C:axon; ISS:UniProtKB.::GO:0043197; C:dendritic spine; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0016328; C:lateral plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0017147; F:Wnt-protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0002548; P:monocyte chemotaxis; IMP:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.::GO:0090260; P:negative regulation of retinal ganglion cell axon guidance; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; ISS:UniProtKB. | 9 | Q12913 | 1337 | PTPRJ_HUMAN Receptor-type tyrosine-protein ph... | 262 | 5e-22 | 102 | 30 | 45 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0060242; P:contact inhibition; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0050918; P:positive chemotaxis; IDA:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0045885; P:positive regulation of survival gene product expression; IDA:UniProtKB. | 10 | P10586 | 1907 | PTPRF_HUMAN Receptor-type tyrosine-protein ph... | 332 | 2e-16 | 85.1 | 26 | 40 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 11 | Q13332 | 1948 | PTPRS_HUMAN Receptor-type tyrosine-protein ph... | 268 | 2e-16 | 84.7 | 28 | 42 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 12 | Q62130 | 1189 | PTN14_MOUSE Tyrosine-protein phosphatase non-... | 368 | 1e-21 | 100 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0001946; P:lymphangiogenesis; IMP:UniProtKB. | 13 | A7MBJ4 | 1898 | PTPRF_BOVIN Receptor-type tyrosine-protein ph... | 311 | 8e-17 | 85.9 | 26 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 14 | O55082 | 426 | PTN20_MOUSE Tyrosine-protein phosphatase non-... | 332 | 3e-21 | 97.4 | 24 | 40 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 15 | Q64604 | 1898 | PTPRF_RAT Receptor-type tyrosine-protein phos... | 323 | 2e-16 | 84.7 | 26 | 40 | GO:0005768; C:endosome; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:RGD.::GO:0031345; P:negative regulation of cell projection organization; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IMP:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0051387; P:negative regulation of nerve growth factor receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0050803; P:regulation of synapse structure and activity; IMP:RGD. | 16 | P29351 | 595 | PTN6_MOUSE Tyrosine-protein phosphatase non-r... | 326 | 8e-21 | 97.4 | 30 | 44 | GO:0042105; C:alpha-beta T cell receptor complex; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001784; F:phosphotyrosine binding; IPI:MGI.::GO:0042169; F:SH2 domain binding; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IMP:MGI.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:MGI.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:MGI.::GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:MGI.::GO:0043409; P:negative regulation of MAPK cascade; IMP:MGI.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0042130; P:negative regulation of T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB. | 17 | Q4JDL3 | 420 | PTN20_HUMAN Tyrosine-protein phosphatase non-... | 374 | 1e-20 | 96.3 | 26 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 18 | A4IFW2 | 1909 | PTPRF_DANRE Receptor-type tyrosine-protein ph... | 323 | 2e-16 | 84.7 | 26 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 19 | A2A8L5 | 1898 | PTPRF_MOUSE Receptor-type tyrosine-protein ph... | 366 | 1e-16 | 85.5 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 20 | E9Q612 | 1226 | PTPRO_MOUSE Receptor-type tyrosine-protein ph... | 261 | 2e-20 | 96.7 | 30 | 44 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0043197; C:dendritic spine; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016328; C:lateral plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0017147; F:Wnt-protein binding; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; IMP:UniProtKB.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0002548; P:monocyte chemotaxis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; IMP:UniProtKB. | 21 | Q9WU22 | 926 | PTN4_MOUSE Tyrosine-protein phosphatase non-r... | 334 | 2e-20 | 96.7 | 27 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | | 22 | P81718 | 613 | PTN6_RAT Tyrosine-protein phosphatase non-rec... | 326 | 6e-20 | 95.1 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046703; F:natural killer cell lectin-like receptor binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD. | 23 | A2ALK8 | 913 | PTN3_MOUSE Tyrosine-protein phosphatase non-r... | 327 | 8e-20 | 95.1 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 24 | Q9BMN8 | 2200 | LAR_CAEEL Tyrosine-protein phosphatase Lar-li... | 325 | 0.000000001 | 63.9 | 25 | 35 | GO:0005912; C:adherens junction; IMP:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:WormBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IMP:UniProtKB.::GO:0008544; P:epidermis development; IMP:WormBase.::GO:0007369; P:gastrulation; IMP:WormBase.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase. | 25 | P26045 | 913 | PTN3_HUMAN Tyrosine-protein phosphatase non-r... | 327 | 1e-19 | 94.7 | 26 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051117; F:ATPase binding; IPI:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL. | 26 | P29074 | 926 | PTN4_HUMAN Tyrosine-protein phosphatase non-r... | 327 | 1e-19 | 94 | 26 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 27 | P18031 | 435 | PTN1_HUMAN Tyrosine-protein phosphatase non-r... | 263 | 2e-19 | 92.8 | 29 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; NAS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030100; P:regulation of endocytosis; IDA:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 28 | P35821 | 432 | PTN1_MOUSE Tyrosine-protein phosphatase non-r... | 263 | 2e-19 | 92.8 | 29 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB. | 29 | P20417 | 432 | PTN1_RAT Tyrosine-protein phosphatase non-rec... | 263 | 2e-19 | 92.4 | 29 | 44 | GO:0031225; C:anchored to membrane; NAS:RGD.::GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IMP:RGD. | 30 | Q98936 | 1422 | PTPRG_CHICK Receptor-type tyrosine-protein ph... | 261 | 3e-19 | 93.6 | 30 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 31 | Q16825 | 1174 | PTN21_HUMAN Tyrosine-protein phosphatase non-... | 321 | 3e-19 | 93.2 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | |
