| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9V9J3 | 517 | SRC42_DROME Tyrosine-protein kinase Src42A OS... | 72 | 0.0003 | 46.2 | 40 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase. | 92 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 76 | 0.29 | 37 | 29 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 93 | O43639 | 380 | NCK2_HUMAN Cytoplasmic protein NCK2 OS=Homo s... | 51 | 0.032 | 39.3 | 35 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB. | 94 | P80667 | 386 | PEX13_YEAST Peroxisomal membrane protein PAS2... | 75 | 0.0005 | 45.1 | 32 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IGI:SGD. | 95 | O88811 | 523 | STAM2_MOUSE Signal transducing adapter molecu... | 68 | 0.0006 | 45.1 | 37 | 60 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 96 | Q5RC07 | 716 | ES8L2_PONAB Epidermal growth factor receptor ... | 60 | 0.0007 | 45.1 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 97 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 60 | 0.0007 | 45.1 | 33 | 53 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 98 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 54 | 0.002 | 43.5 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 99 | Q08509 | 821 | EPS8_MOUSE Epidermal growth factor receptor k... | 55 | 0.002 | 43.9 | 33 | 60 | GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:MGI.::GO:0051017; P:actin filament bundle assembly; IGI:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0048149; P:behavioral response to ethanol; IMP:MGI. | 100 | P25911 | 512 | LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus ... | 55 | 0.002 | 43.5 | 40 | 65 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005128; F:erythropoietin receptor binding; TAS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IPI:MGI. | | | | | | | | | | GO:0001782; P:B cell homeostasis; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0097028; P:dendritic cell differentiation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; IMP:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; IMP:UniProtKB.::GO:0002762; P:negative regulation of myeloid leukocyte differentiation; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; IMP:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0031175; P:neuron projection development; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0002576; P:platelet degranulation; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0050707; P:regulation of cytokine secretion; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:UniProtKB.::GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002513; P:tolerance induction to self antigen; IMP:UniProtKB. | 101 | Q99K30 | 729 | ES8L2_MOUSE Epidermal growth factor receptor ... | 61 | 0.002 | 43.5 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 102 | Q5R4H4 | 822 | EPS8_PONAB Epidermal growth factor receptor k... | 55 | 0.002 | 43.9 | 31 | 60 | | | | | | | | | | | | | | | | | | | | | | 103 | Q07014 | 512 | LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus... | 55 | 0.002 | 43.5 | 40 | 65 | GO:0034666; C:alpha2-beta1 integrin complex; IDA:RGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.::GO:0005758; C:mitochondrial intermembrane space; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043208; F:glycosphingolipid binding; IPI:RGD.::GO:0005178; F:integrin binding; IDA:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD. | | | | | | | | | | GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0034605; P:cellular response to heat; IEP:RGD.::GO:0050663; P:cytokine secretion; IMP:RGD.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0002553; P:histamine secretion by mast cell; IMP:RGD.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0060369; P:positive regulation of Fc receptor mediated stimulatory signaling pathway; IMP:RGD.::GO:0060252; P:positive regulation of glial cell proliferation; IDA:RGD.::GO:0070447; P:positive regulation of oligodendrocyte progenitor proliferation; IMP:RGD.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0009743; P:response to carbohydrate stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006991; P:response to sterol depletion; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB. | 104 | Q12929 | 822 | EPS8_HUMAN Epidermal growth factor receptor k... | 55 | 0.002 | 43.9 | 31 | 60 | | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc. | 105 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 133 | 0.002 | 43.5 | 27 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 106 | O75886 | 525 | STAM2_HUMAN Signal transducing adapter molecu... | 60 | 0.002 | 43.1 | 35 | 62 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 107 | Q5XHY7 | 523 | STAM2_RAT Signal transducing adapter molecule... | 69 | 0.003 | 42.7 | 33 | 59 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 108 | A8XI74 | 277 | CED2_CAEBR Cell death abnormality protein 2 O... | 40 | 0.003 | 42.4 | 40 | 70 | | | | | | | | | | | GO:0032403; F:protein complex binding; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043652; P:engulfment of apoptotic cell; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB. | 109 | Q63356 | 1107 | MYO1E_RAT Unconventional myosin-Ie OS=Rattus ... | 148 | 0.003 | 43.1 | 25 | 39 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0003094; P:glomerular filtration; ISS:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB. | 110 | Q6BNP6 | 512 | HSE1_DEBHA Class E vacuolar protein-sorting m... | 73 | 0.003 | 42.7 | 33 | 53 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 111 | Q9NHC3 | 279 | CED2_CAEEL Cell death abnormality protein 2 O... | 40 | 0.004 | 42 | 40 | 70 | GO:0005886; C:plasma membrane; NAS:WormBase. | | | | | | | | | | GO:0032403; F:protein complex binding; IPI:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0043652; P:engulfment of apoptotic cell; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB. | 112 | E9Q634 | 1107 | MYO1E_MOUSE Unconventional myosin-Ie OS=Mus m... | 207 | 0.004 | 42.7 | 26 | 37 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0003094; P:glomerular filtration; IMP:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0035166; P:post-embryonic hemopoiesis; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI. | 113 | P07948 | 512 | LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo... | 55 | 0.004 | 42.4 | 40 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0070668; P:positive regulation of mast cell proliferation; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0070304; P:positive regulation of stress-activated protein kinase signaling cascade; IDA:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090025; P:regulation of monocyte chemotaxis; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB. | 114 | P05433 | 440 | GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc... | 53 | 0.005 | 42 | 38 | 57 | GO:0019028; C:viral capsid; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 115 | Q9XVN3 | 769 | IASPP_CAEEL Apoptotic enhancer 1 protein OS=C... | 58 | 0.006 | 42 | 40 | 55 | GO:0005634; C:nucleus; ISS:WormBase. | | | | | | | | | | GO:0002039; F:p53 binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase. | 116 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 68 | 0.006 | 42 | 37 | 54 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 117 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 53 | 0.007 | 41.2 | 36 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 118 | P70297 | 548 | STAM1_MOUSE Signal transducing adapter molecu... | 55 | 0.008 | 41.6 | 36 | 64 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 119 | Q9NYB9 | 513 | ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (... | 60 | 0.009 | 41.2 | 35 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI. | 120 | Q7S6J4 | 745 | HSE1_NEUCR Class E vacuolar protein-sorting m... | 94 | 0.009 | 41.6 | 33 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 121 | O93436 | 468 | STAM2_CHICK Signal transducing adapter molecu... | 55 | 0.01 | 41.2 | 38 | 64 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |
