Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
197139
Length:
332
Number of sequences:
10438
Description:
estExt_Genewise1Plus.C_10899
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q62077    1302   PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho...720.1     38.1     29     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
182Q5BBL4    581   HSE1_EMENI Class E vacuolar protein-sorting m...560.11     38.1     34     54GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
183P02549    2419   SPTA1_HUMAN Spectrin alpha chain, erythrocyte...610.11     38.1     31     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; TAS:BHF-UCL.::GO:0008091; C:spectrin; TAS:ProtInc.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL.
GO:0051015; F:actin filament binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007015; P:actin filament organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
184Q03526    625   ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=...510.11     38.1     37     55GO:0005829; C:cytosol; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IMP:MGI.::GO:0032633; P:interleukin-4 production; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001865; P:NK T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.
185Q13588    217   GRAP_HUMAN GRB2-related adapter protein OS=Ho...540.11     37.4     28     67GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
186O43150    1006   ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe...1000.11     38.1     30     50GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
187A6QLK6    217   GRAP_BOVIN GRB2-related adapter protein OS=Bo...640.11     37.4     27     63
188P42690    506   SRK4_SPOLA Tyrosine-protein kinase isoform SR...520.12     37.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
189P42686    505   SRK1_SPOLA Tyrosine-protein kinase isoform SR...520.12     37.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
190P29355    228   SEM5_CAEEL Sex muscle abnormal protein 5 OS=C...430.18     36.6     37     67
GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.
191Q557J6    481   DBNL_DICDI Drebrin-like protein OS=Dictyostel...580.12     37.7     33     57GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:dictyBase.::GO:0032037; F:myosin I heavy chain binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0031269; P:pseudopodium assembly; IMP:dictyBase.
192Q92882    214   OSTF1_HUMAN Osteoclast-stimulating factor 1 O...530.14     37     38     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
193O00160    1098   MYO1F_HUMAN Unconventional myosin-If OS=Homo ...640.14     37.7     31     50GO:0016461; C:unconventional myosin complex; NAS:UniProtKB.
GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.
194Q63767    968   BCAR1_RAT Breast cancer anti-estrogen resista...590.15     37.7     32     58GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
195P08487    1291   PLCG1_BOVIN 1-phosphatidylinositol 4,5-bispho...720.15     37.7     29     47GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:AgBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.
196P12931    536   SRC_HUMAN Proto-oncogene tyrosine-protein kin...530.15     37.4     40     57GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:BHF-UCL.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome.
197Q61140    874   BCAR1_MOUSE Breast cancer anti-estrogen resis...590.15     37.7     32     58GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
198A5GFW5    784   CASS4_PIG Cas scaffolding protein family memb...620.15     37.7     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
199Q62422    215   OSTF1_MOUSE Osteoclast-stimulating factor 1 O...520.16     36.6     37     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IDA:MGI.
200Q8MJ50    214   OSTF1_BOVIN Osteoclast-stimulating factor 1 O...530.16     36.6     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
201P14084    568   SRC_AVISS Tyrosine-protein kinase transformin...530.16     37.4     40     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
202Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...520.16     36.6     37     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
203P06239    509   LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo...660.16     37.4     32     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.::GO:0042610; F:CD8 receptor binding; IPI:UniProtKB.::GO:0001948; F:glycoprotein binding; IPI:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; IEP:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; NAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0030217; P:T cell differentiation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
204P00523    533   SRC_CHICK Proto-oncogene tyrosine-protein kin...530.17     37.4     40     55GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
205P00524    526   SRC_RSVSA Tyrosine-protein kinase transformin...530.17     37.4     40     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
206P00525    526   SRC_AVISR Tyrosine-protein kinase transformin...530.17     37.4     40     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
207Q13813    2472   SPTA2_HUMAN Spectrin alpha chain, brain OS=Ho...910.17     37.7     26     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0008091; C:spectrin; TAS:ProtInc.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.
208P07751    2477   SPTA2_CHICK Spectrin alpha chain, brain OS=Ga...910.17     37.7     26     42GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
209A3LXQ8    475   HSE1_PICST Class E vacuolar protein-sorting m...550.18     37.4     35     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
210Q5ZJJ9    202   OSTF1_CHICK Osteoclast-stimulating factor 1 O...530.18     36.6     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
211Q8MJ49    214   OSTF1_PIG Osteoclast-stimulating factor 1 OS=...530.18     36.6     38     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
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