| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | D3Z8D9 | 211 | MD2L2_RAT Mitotic spindle assembly checkpoint... | 179 | 6e-24 | 98.6 | 33 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008432; F:JUN kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q9D752 | 211 | MD2L2_MOUSE Mitotic spindle assembly checkpoi... | 179 | 6e-24 | 98.6 | 33 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008432; F:JUN kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q2KIP7 | 211 | MD2L2_BOVIN Mitotic spindle assembly checkpoi... | 179 | 2e-23 | 97.1 | 33 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008432; F:JUN kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q4KWZ6 | 211 | MD2L2_CHICK Mitotic spindle assembly checkpoi... | 179 | 1e-22 | 95.1 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | GO:0017125; F:deoxycytidyl transferase activity; ISS:AgBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0042276; P:error-prone translesion synthesis; ISS:AgBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; IMP:UniProtKB.::GO:0009411; P:response to UV; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q8QFR4 | 211 | MD2L2_XENLA Mitotic spindle assembly checkpoi... | 179 | 2e-22 | 94.7 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; IDA:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0009794; P:regulation of mitotic cell cycle, embryonic; IMP:UniProtKB.::GO:0043393; P:regulation of protein binding; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q9UI95 | 211 | MD2L2_HUMAN Mitotic spindle assembly checkpoi... | 179 | 2e-22 | 94.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; IDA:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; IDA:UniProtKB. | | | | | | | | | | GO:0008432; F:JUN kinase binding; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; IDA:UniProtKB.::GO:0006302; P:double-strand break repair; IGI:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:ProtInc.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0001558; P:regulation of cell growth; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q28H85 | 211 | MD2L2_XENTR Mitotic spindle assembly checkpoi... | 179 | 3e-22 | 94.4 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q0E7J8 | 213 | REV7_SCHPO DNA polymerase zeta processivity s... | 178 | 1e-21 | 92.4 | 32 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 9 | Q568H3 | 211 | MD2L2_DANRE Mitotic spindle assembly checkpoi... | 178 | 2e-21 | 92 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q54S00 | 332 | MD2L2_DICDI Mitotic spindle assembly checkpoi... | 87 | 0.000000000006 | 66.2 | 34 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 11 | P40958 | 196 | MAD2_YEAST Mitotic spindle checkpoint compone... | 100 | 0.0000000005 | 59.3 | 29 | 59 | GO:0033597; C:mitotic checkpoint complex; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051312; P:chromosome decondensation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:SGD. | 12 | Q556Y9 | 203 | MD2L1_DICDI Mitotic spindle assembly checkpoi... | 85 | 0.000000004 | 57 | 32 | 58 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:dictyBase. | 13 | Q9Z1B5 | 205 | MD2L1_MOUSE Mitotic spindle assembly checkpoi... | 94 | 0.00000003 | 54.7 | 31 | 60 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0000922; C:spindle pole; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:MGI.::GO:0000070; P:mitotic sister chromatid segregation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB. | 14 | Q13257 | 205 | MD2L1_HUMAN Mitotic spindle assembly checkpoi... | 101 | 0.0000001 | 53.1 | 28 | 56 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB. | 15 | O14417 | 203 | MAD2_SCHPO Mitotic spindle checkpoint compone... | 166 | 0.0000005 | 51.2 | 27 | 50 | GO:0000778; C:condensed nuclear chromosome kinetochore; TAS:PomBase.::GO:0033597; C:mitotic checkpoint complex; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase. | 16 | Q9LU93 | 209 | MAD2_ARATH Mitotic spindle checkpoint protein... | 95 | 0.0000007 | 50.8 | 28 | 56 | GO:0010369; C:chromocenter; IDA:TAIR.::GO:0000776; C:kinetochore; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IDA:TAIR. | 17 | Q9XFH3 | 208 | MAD2_MAIZE Mitotic spindle checkpoint protein... | 111 | 0.000005 | 48.5 | 27 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 18 | P38927 | 245 | REV7_YEAST DNA polymerase zeta processivity s... | 121 | 0.013 | 38.9 | 28 | 46 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0016035; C:zeta DNA polymerase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0070987; P:error-free translesion synthesis; IDA:SGD.::GO:0042276; P:error-prone translesion synthesis; IDA:SGD. | 19 | A1RSF1 | 593 | VATA_PYRIL V-type ATP synthase alpha chain OS... | 59 | 3.6 | 32 | 34 | 51 | GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro. | | | | | | | | | | GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. |
