rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
601 | Q61846 | 643 | MELK_MOUSE Maternal embryonic leucine zipper ... | 104 | 0.0000000006 | 65.1 | 38 | 52 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 602 | Q8BYR2 | 1129 | LATS1_MOUSE Serine/threonine-protein kinase L... | 121 | 0.0000000006 | 65.5 | 34 | 49 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.::GO:0000819; P:sister chromatid segregation; ISS:UniProtKB. | 603 | P36002 | 662 | PTK1_YEAST Serine/threonine-protein kinase PT... | 112 | 0.0000000006 | 65.1 | 34 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015846; P:polyamine transport; IMP:SGD. | 604 | Q54LR6 | 605 | Y6481_DICDI Probable serine/threonine-protein... | 181 | 0.0000000006 | 65.1 | 31 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | | 605 | P53681 | 602 | CRK_DAUCA CDPK-related protein kinase OS=Dauc... | 197 | 0.0000000006 | 64.7 | 30 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 606 | O59854 | 407 | HOG1_ZYGRO Mitogen-activated protein kinase H... | 216 | 0.0000000006 | 64.3 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 607 | Q2U469 | 344 | MPKC_ASPOR Mitogen-activated protein kinase m... | 177 | 0.0000000006 | 63.9 | 28 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 608 | Q8RWC9 | 444 | CIPK1_ARATH CBL-interacting serine/threonine-... | 181 | 0.0000000006 | 64.3 | 28 | 41 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 609 | Q38873 | 535 | CDPK7_ARATH Calcium-dependent protein kinase ... | 188 | 0.0000000006 | 64.7 | 28 | 46 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 610 | Q9LEU7 | 445 | CIPK5_ARATH CBL-interacting serine/threonine-... | 197 | 0.0000000006 | 64.3 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 611 | Q8VDF3 | 370 | DAPK2_MOUSE Death-associated protein kinase 2... | 216 | 0.0000000007 | 64.3 | 28 | 44 | GO:0034423; C:autophagic vacuole lumen; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 612 | O94737 | 370 | MAPK1_PNECA Mitogen-activated protein kinase ... | 104 | 0.0000000007 | 64.3 | 34 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043008; F:ATP-dependent protein binding; IPI:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016043; P:cellular component organization; IMP:UniProtKB.::GO:0040010; P:positive regulation of growth rate; IMP:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB. | 613 | Q5ZKI0 | 479 | KCC2D_CHICK Calcium/calmodulin-dependent prot... | 218 | 0.0000000007 | 64.7 | 28 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 614 | O93982 | 431 | HOG1_ZYGRC Mitogen-activated protein kinase H... | 215 | 0.0000000007 | 64.3 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 615 | Q9Z1M4 | 485 | KS6B2_MOUSE Ribosomal protein S6 kinase beta-... | 202 | 0.0000000007 | 64.7 | 29 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 616 | Q64303 | 524 | PAK2_RAT Serine/threonine-protein kinase PAK ... | 174 | 0.0000000007 | 64.7 | 29 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 617 | P22612 | 351 | KAPCG_HUMAN cAMP-dependent protein kinase cat... | 181 | 0.0000000007 | 63.9 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0008584; P:male gonad development; TAS:ProtInc.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 618 | Q8CIN4 | 524 | PAK2_MOUSE Serine/threonine-protein kinase PA... | 174 | 0.0000000007 | 64.7 | 29 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 619 | O15530 | 556 | PDPK1_HUMAN 3-phosphoinositide-dependent prot... | 183 | 0.0000000007 | 64.7 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 620 | P49187 | 464 | MK10_RAT Mitogen-activated protein kinase 10 ... | 178 | 0.0000000007 | 64.3 | 26 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB. | | | | | | | | | | | 621 | Q15131 | 360 | CDK10_HUMAN Cyclin-dependent kinase 10 OS=Hom... | 214 | 0.0000000007 | 63.9 | 30 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc. | 622 | Q96RG2 | 1323 | PASK_HUMAN PAS domain-containing serine/threo... | 174 | 0.0000000008 | 65.1 | 32 | 45 | GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0070092; P:regulation of glucagon secretion; ISS:UniProtKB.::GO:0043576; P:regulation of respiratory gaseous exchange; ISS:UniProtKB. | 623 | Q4KM47 | 358 | CDK10_RAT Cyclin-dependent kinase 10 OS=Rattu... | 214 | 0.0000000008 | 63.9 | 30 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 624 | O13945 | 532 | PPK9_SCHPO Protein kinase domain-containing p... | 174 | 0.0000000008 | 64.3 | 32 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0007165; P:signal transduction; NAS:PomBase. | 625 | Q86AD7 | 392 | MYLKB_DICDI Probable myosin light chain kinas... | 226 | 0.0000000008 | 63.9 | 28 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. | 626 | P22517 | 447 | KCC2_YEAST Calcium/calmodulin-dependent prote... | 225 | 0.0000000008 | 64.3 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD. | | | | | | | | | | GO:0007165; P:signal transduction; NAS:SGD. | 627 | Q84VQ3 | 439 | CIPKQ_ARATH CBL-interacting serine/threonine-... | 213 | 0.0000000008 | 64.3 | 26 | 42 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 628 | Q29502 | 524 | PAK2_RABIT Serine/threonine-protein kinase PA... | 173 | 0.0000000008 | 64.3 | 29 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB. | 629 | B3M6I4 | 770 | PLK4_DROAN Serine/threonine-protein kinase PL... | 183 | 0.0000000008 | 64.7 | 31 | 45 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 630 | P06244 | 397 | KAPA_YEAST cAMP-dependent protein kinase type... | 201 | 0.0000000008 | 63.9 | 28 | 45 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IMP:SGD. | 631 | P28708 | 518 | PRR1_YEAST Serine/threonine-protein kinase PR... | 212 | 0.0000000008 | 64.3 | 25 | 39 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IMP:SGD. | | | | | | | | | | GO:0031138; P:negative regulation of conjugation with cellular fusion; IMP:SGD.::GO:0046020; P:negative regulation of transcription from RNA polymerase II promoter by pheromones; IMP:SGD. |