rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O42645 | 351 | YF94_SCHPO RCC1 repeat-containing protein C10... | 455 | 0.00000002 | 59.7 | 22 | 36 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007017; P:microtubule-based process; ISS:PomBase.::GO:0006400; P:tRNA modification; ISS:PomBase. | 2 | Q9UGK8 | 458 | SRGEF_HUMAN Secretion-regulating guanine nucl... | 336 | 0.000001 | 54.3 | 24 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; IDA:HGNC.::GO:0007165; P:signal transduction; TAS:UniProtKB. | 3 | Q80YD6 | 464 | SRGEF_MOUSE Secretion-regulating guanine nucl... | 473 | 0.000002 | 53.1 | 24 | 37 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | Q15034 | 1050 | HERC3_HUMAN Probable E3 ubiquitin-protein lig... | 428 | 0.000005 | 52.8 | 23 | 38 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 5 | Q9CYF5 | 461 | WBS16_MOUSE Williams-Beuren syndrome chromoso... | 109 | 0.00008 | 48.5 | 36 | 50 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | | 6 | Q5RCZ7 | 551 | RCBT2_PONAB RCC1 and BTB domain-containing pr... | 154 | 3.5 | 33.9 | 25 | 42 | | | | | | | | | | | | | | | | | | | | | | 7 | O95199 | 551 | RCBT2_HUMAN RCC1 and BTB domain-containing pr... | 154 | 3.5 | 33.9 | 25 | 42 | | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | | 8 | Q5GLZ8 | 1057 | HERC4_HUMAN Probable E3 ubiquitin-protein lig... | 435 | 0.11 | 38.9 | 22 | 35 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 9 | Q3MHW0 | 464 | SRGEF_BOVIN Secretion-regulating guanine nucl... | 472 | 0.0003 | 46.6 | 23 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q96I51 | 464 | WBS16_HUMAN Williams-Beuren syndrome chromoso... | 109 | 0.0004 | 46.2 | 34 | 52 | | | | | | | | | | | | | | | | | | | | | | 11 | Q6P798 | 551 | RCBT2_RAT RCC1 and BTB domain-containing prot... | 156 | 0.62 | 36.2 | 27 | 42 | | | | | | | | | | | | | | | | | | | | | | 12 | Q99LJ7 | 551 | RCBT2_MOUSE RCC1 and BTB domain-containing pr... | 156 | 0.44 | 36.6 | 27 | 43 | | | | | | | | | | | | | | | | | | | | | | 13 | Q8IVU3 | 1022 | HERC6_HUMAN Probable E3 ubiquitin-protein lig... | 182 | 3 | 34.3 | 25 | 41 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 14 | Q6NXM2 | 531 | RCBT1_MOUSE RCC1 and BTB domain-containing pr... | 161 | 3.3 | 33.9 | 22 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q8NDN9 | 531 | RCBT1_HUMAN RCC1 and BTB domain-containing pr... | 108 | 0.87 | 35.8 | 27 | 48 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q54X24 | 512 | RCCDA_DICDI RCC1 domain-containing protein DD... | 193 | 2.4 | 34.3 | 20 | 40 | | | | | | | | | | | | | | | | | | | | | | 17 | Q08023 | 583 | FMP25_YEAST Protein FMP25, mitochondrial OS=S... | 62 | 3.3 | 33.9 | 31 | 55 | GO:0031305; C:integral to mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0034551; P:mitochondrial respiratory chain complex III assembly; IMP:SGD. | 18 | Q6PAV2 | 1057 | HERC4_MOUSE Probable E3 ubiquitin-protein lig... | 462 | 0.066 | 39.7 | 22 | 36 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 19 | Q5PQN1 | 1057 | HERC4_RAT Probable E3 ubiquitin-protein ligas... | 462 | 0.019 | 41.2 | 22 | 37 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 20 | Q9UII4 | 1024 | HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS... | 225 | 0.006 | 43.1 | 24 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 21 | Q54HT1 | 1336 | TIRA_DICDI Protein tirA OS=Dictyostelium disc... | 109 | 0.01 | 42.4 | 29 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006952; P:defense response; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 22 | Q15751 | 4861 | HERC1_HUMAN Probable E3 ubiquitin-protein lig... | 213 | 5.7 | 33.5 | 24 | 37 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 23 | Q9VR91 | 4912 | HERC2_DROME Probable E3 ubiquitin-protein lig... | 126 | 0.024 | 41.2 | 27 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 24 | P31386 | 333 | ATS1_YEAST Protein ATS1 OS=Saccharomyces cere... | 120 | 4.5 | 33.1 | 31 | 43 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0007117; P:budding cell bud growth; IGI:SGD.::GO:0000226; P:microtubule cytoskeleton organization; IMP:SGD.::GO:0002098; P:tRNA wobble uridine modification; IMP:SGD. | 25 | Q8TD19 | 979 | NEK9_HUMAN Serine/threonine-protein kinase Ne... | 128 | 0.21 | 37.7 | 25 | 47 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 26 | Q8K1R7 | 984 | NEK9_MOUSE Serine/threonine-protein kinase Ne... | 128 | 0.25 | 37.7 | 25 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 27 | Q92834 | 1020 | RPGR_HUMAN X-linked retinitis pigmentosa GTPa... | 203 | 0.35 | 37.4 | 24 | 38 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.::GO:0001750; C:photoreceptor outer segment; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; TAS:ProtInc.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IMP:UniProtKB. | 28 | O95714 | 4834 | HERC2_HUMAN E3 ubiquitin-protein ligase HERC2... | 130 | 7.7 | 33.1 | 26 | 40 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 29 | Q4U2R1 | 4836 | HERC2_MOUSE E3 ubiquitin-protein ligase HERC2... | 130 | 8.9 | 32.7 | 26 | 40 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI. | 30 | Q8IS20 | 1457 | GEFC_DICDI Ras guanine nucleotide exchange fa... | 51 | 0.5 | 36.6 | 35 | 61 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 31 | Q17551 | 3766 | RPM1_CAEEL E3 ubiquitin-protein ligase rpm-1 ... | 53 | 0.51 | 37 | 34 | 58 | GO:0030424; C:axon; IDA:WormBase.::GO:0031594; C:neuromuscular junction; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0043409; P:negative regulation of MAPK cascade; IGI:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0031647; P:regulation of protein stability; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |