rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P41251 | 548 | NRAM1_MOUSE Natural resistance-associated mac... | 528 | 8e-38 | 150 | 29 | 44 | GO:0009279; C:cell outer membrane; IDA:MGI.::GO:0010008; C:endosome membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:MGI.::GO:0030670; C:phagocytic vesicle membrane; IDA:MGI.::GO:0005773; C:vacuole; IMP:GOC. | | | | | | | | | | GO:0005384; F:manganese ion transmembrane transporter activity; IMP:MGI. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; IMP:MGI.::GO:0048002; P:antigen processing and presentation of peptide antigen; IMP:MGI.::GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0050829; P:defense response to Gram-negative bacterium; IMP:MGI.::GO:0042832; P:defense response to protozoan; IMP:MGI.::GO:0070839; P:divalent metal ion export; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0032623; P:interleukin-2 production; IMP:MGI.::GO:0032632; P:interleukin-3 production; IMP:MGI.::GO:0006826; P:iron ion transport; IMP:MGI.::GO:0043091; P:L-arginine import; IDA:MGI.::GO:0042116; P:macrophage activation; IDA:MGI.::GO:0045342; P:MHC class II biosynthetic process; IMP:MGI.::GO:0048255; P:mRNA stabilization; IMP:MGI.::GO:0060586; P:multicellular organismal iron ion homeostasis; IMP:MGI.::GO:0001818; P:negative regulation of cytokine production; IMP:MGI.::GO:0015707; P:nitrite transport; IDA:MGI.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0032729; P:positive regulation of interferon-gamma production; IMP:MGI.::GO:0050766; P:positive regulation of phagocytosis; IMP:MGI.::GO:0002827; P:positive regulation of T-helper 1 type immune response; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0000060; P:protein import into nucleus, translocation; IMP:MGI.::GO:0045730; P:respiratory burst; IDA:MGI.::GO:0034341; P:response to interferon-gamma; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0002369; P:T cell cytokine production; IMP:MGI.::GO:0002309; P:T cell proliferation involved in immune response; IMP:MGI.::GO:0007035; P:vacuolar acidification; IMP:MGI.::GO:0042060; P:wound healing; IMP:MGI. | 32 | Q27946 | 548 | NRAM1_BUBBU Natural resistance-associated mac... | 469 | 1e-37 | 149 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 33 | Q8UEM1 | 461 | MNTH_AGRT5 Probable manganese transport prote... | 196 | 3e-25 | 112 | 38 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 34 | Q27981 | 548 | NRAM1_BOVIN Natural resistance-associated mac... | 462 | 8e-37 | 147 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 35 | Q10Q65 | 524 | NRAM2_ORYSJ Metal transporter Nramp2 OS=Oryza... | 466 | 8e-37 | 147 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 36 | P49280 | 548 | NRAM1_SHEEP Natural resistance-associated mac... | 460 | 1e-36 | 146 | 31 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 37 | Q2YX69 | 450 | MNTH_STAAB Probable manganese transport prote... | 154 | 6e-22 | 102 | 41 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | P49282 | 568 | NRAM2_MOUSE Natural resistance-associated mac... | 462 | 6e-36 | 144 | 31 | 47 | GO:0005903; C:brush border; IDA:MGI.::GO:0009986; C:cell surface; IDA:MGI.::GO:0005769; C:early endosome; IDA:MGI.::GO:0012505; C:endomembrane system; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; IDA:MGI.::GO:0055037; C:recycling endosome; IDA:MGI. | | | | | | | | | | GO:0015087; F:cobalt ion transmembrane transporter activity; IDA:MGI.::GO:0015093; F:ferrous iron transmembrane transporter activity; IDA:MGI.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IDA:MGI. | | | | | | | | | | GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0048821; P:erythrocyte development; IMP:MGI.::GO:0070627; P:ferrous iron import; IDA:MGI.::GO:0006783; P:heme biosynthetic process; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0060586; P:multicellular organismal iron ion homeostasis; IMP:MGI. | 39 | Q9C6B2 | 530 | NRAM2_ARATH Metal transporter Nramp2 OS=Arabi... | 460 | 6e-36 | 144 | 28 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 40 | Q9FN18 | 512 | NRAM4_ARATH Metal transporter Nramp4 OS=Arabi... | 460 | 8e-36 | 144 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IGI:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0006828; P:manganese ion transport; IMP:TAIR.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IGI:TAIR.::GO:0010039; P:response to iron ion; IEP:TAIR.::GO:0009624; P:response to nematode; IEP:TAIR. | 41 | Q5HQ64 | 453 | MNTH_STAEQ Probable manganese transport prote... | 191 | 8e-22 | 102 | 37 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 42 | Q9SNV9 | 509 | NRAM3_ARATH Metal transporter Nramp3 OS=Arabi... | 460 | 1e-35 | 142 | 29 | 45 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0055072; P:iron ion homeostasis; IMP:TAIR.::GO:0006828; P:manganese ion transport; IMP:TAIR.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IGI:TAIR.::GO:0010043; P:response to zinc ion; IEP:TAIR. | 43 | Q9XT74 | 547 | NRAM1_CANFA Natural resistance-associated mac... | 461 | 1e-35 | 143 | 31 | 47 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005384; F:manganese ion transmembrane transporter activity; NAS:UniProtKB. | | | | | | | | | | | 44 | O54902 | 568 | NRAM2_RAT Natural resistance-associated macro... | 462 | 2e-35 | 143 | 31 | 47 | GO:0031902; C:late endosome membrane; IDA:RGD.::GO:0005765; C:lysosomal membrane; IDA:RGD. | | | | | | | | | | GO:0046870; F:cadmium ion binding; IDA:RGD.::GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:RGD.::GO:0050897; F:cobalt ion binding; IDA:RGD.::GO:0015087; F:cobalt ion transmembrane transporter activity; IDA:RGD.::GO:0005507; F:copper ion binding; IDA:RGD.::GO:0005375; F:copper ion transmembrane transporter activity; IDA:RGD.::GO:0015093; F:ferrous iron transmembrane transporter activity; IMP:RGD.::GO:0005506; F:iron ion binding; IDA:RGD.::GO:0015094; F:lead ion transmembrane transporter activity; IDA:RGD.::GO:0030145; F:manganese ion binding; IDA:RGD.::GO:0005384; F:manganese ion transmembrane transporter activity; IDA:RGD.::GO:0016151; F:nickel cation binding; IDA:RGD.::GO:0015099; F:nickel cation transmembrane transporter activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071281; P:cellular response to iron ion; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0010042; P:response to manganese ion; IMP:RGD. | 45 | Q8Y773 | 448 | MNTH_LISMO Probable manganese transport prote... | 181 | 9e-26 | 113 | 42 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 46 | B8DE85 | 448 | MNTH_LISMH Probable manganese transport prote... | 181 | 9e-26 | 113 | 42 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | Q71ZP6 | 448 | MNTH_LISMF Probable manganese transport prote... | 181 | 9e-26 | 113 | 42 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | C1L2Y0 | 448 | MNTH_LISMC Probable manganese transport prote... | 181 | 9e-26 | 113 | 42 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 49 | A0AIM7 | 448 | MNTH_LISW6 Probable manganese transport prote... | 181 | 1e-25 | 113 | 42 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | Q92BT1 | 448 | MNTH_LISIN Probable manganese transport prote... | 175 | 1e-25 | 113 | 43 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 51 | Q8CPM6 | 453 | MNTH_STAES Probable manganese transport prote... | 191 | 8e-22 | 102 | 37 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 52 | P65545 | 456 | MNTH_BRUSU Probable manganese transport prote... | 184 | 2e-24 | 110 | 40 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 53 | P65544 | 456 | MNTH_BRUME Probable manganese transport prote... | 184 | 2e-24 | 110 | 40 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 54 | Q9SN36 | 530 | NRAM5_ARATH Metal transporter Nramp5 OS=Arabi... | 508 | 8e-35 | 140 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 55 | Q03D26 | 458 | MNTH_LACC3 Probable manganese transport prote... | 186 | 4e-21 | 100 | 38 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | B3W6P3 | 458 | MNTH_LACCB Probable manganese transport prote... | 186 | 3e-21 | 100 | 38 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | Q93V04 | 464 | MNTH_LACBR Manganese transport protein MntH O... | 148 | 9e-20 | 95.9 | 39 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 58 | Q38UX8 | 458 | MNTH_LACSS Probable manganese transport prote... | 180 | 3e-20 | 97.4 | 35 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | Q8XSF6 | 442 | MNTH_RALSO Probable manganese transport prote... | 153 | 4e-25 | 111 | 45 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | Q9SAH8 | 532 | NRAM1_ARATH Metal transporter Nramp1 OS=Arabi... | 139 | 3e-21 | 100 | 43 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:UniProtKB.::GO:0005384; F:manganese ion transmembrane transporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0055071; P:manganese ion homeostasis; IMP:TAIR. | 61 | Q9S9N8 | 527 | NRAM6_ARATH Metal transporter Nramp6 OS=Arabi... | 168 | 1e-20 | 99 | 41 | 57 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. |