rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q10177 | 521 | PDT1_SCHPO Manganese transporter pdt1 OS=Schi... | 481 | 4e-96 | 309 | 42 | 56 | GO:0030176; C:integral to endoplasmic reticulum membrane; IC:PomBase. | | | | | | | | | | GO:0005384; F:manganese ion transmembrane transporter activity; TAS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030026; P:cellular manganese ion homeostasis; IGI:PomBase. | 2 | P38778 | 549 | SMF2_YEAST Manganese transporter SMF2 OS=Sacc... | 581 | 1e-89 | 293 | 36 | 52 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0022890; F:inorganic cation transmembrane transporter activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006877; P:cellular cobalt ion homeostasis; IGI:SGD.::GO:0030026; P:cellular manganese ion homeostasis; IMP:SGD.::GO:0006824; P:cobalt ion transport; IGI:SGD.::GO:0006828; P:manganese ion transport; IMP:SGD. | 3 | P38925 | 575 | SMF1_YEAST Manganese transporter SMF1 OS=Sacc... | 579 | 1e-84 | 280 | 34 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0022890; F:inorganic cation transmembrane transporter activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015295; F:solute:hydrogen symporter activity; IDA:SGD. | | | | | | | | | | GO:0015691; P:cadmium ion transport; IGI:SGD.::GO:0006876; P:cellular cadmium ion homeostasis; IGI:SGD.::GO:0006878; P:cellular copper ion homeostasis; IGI:SGD.::GO:0030026; P:cellular manganese ion homeostasis; IMP:SGD.::GO:0006825; P:copper ion transport; IGI:SGD.::GO:0006828; P:manganese ion transport; IMP:SGD. | 4 | Q12078 | 473 | SMF3_YEAST Iron transporter SMF3 OS=Saccharom... | 538 | 5e-80 | 265 | 34 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046873; F:metal ion transmembrane transporter activity; ISS:SGD. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.::GO:0006826; P:iron ion transport; IMP:SGD. | 5 | Q8ZSB0 | 442 | MNTH_NOSS1 Probable manganese transport prote... | 476 | 3e-67 | 230 | 37 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | Q4L5B9 | 446 | MNTH_STAHJ Probable manganese transport prote... | 482 | 1e-59 | 210 | 34 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q7A166 | 450 | MNTH_STAAW Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q6GAA9 | 450 | MNTH_STAAS Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q99UZ7 | 450 | MNTH_STAAN Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | A6QFW1 | 450 | MNTH_STAAE Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | Q5HGX9 | 450 | MNTH_STAAC Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 12 | A5IRZ2 | 450 | MNTH_STAA9 Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q2G2G3 | 450 | MNTH_STAA8 Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q2FHX5 | 450 | MNTH_STAA3 Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | A6U0S3 | 450 | MNTH_STAA2 Probable manganese transport prote... | 472 | 8e-59 | 208 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | Q931T9 | 450 | MNTH_STAAM Probable manganese transport prote... | 472 | 1e-58 | 207 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | A7X111 | 450 | MNTH_STAA1 Probable manganese transport prote... | 472 | 1e-58 | 207 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q6GHY0 | 450 | MNTH_STAAR Probable manganese transport prote... | 472 | 3e-54 | 196 | 33 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | Q03TH5 | 459 | MNTH_LACBA Probable manganese transport prote... | 465 | 6e-52 | 189 | 35 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | Q553K4 | 629 | NRAM2_DICDI Natural resistance-associated mac... | 468 | 1e-50 | 189 | 33 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q03DK0 | 447 | MNTH_PEDPA Probable manganese transport prote... | 458 | 5e-50 | 184 | 35 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | Q98I99 | 454 | MNTH_RHILO Probable manganese transport prote... | 456 | 4e-47 | 176 | 33 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 23 | Q8P8R8 | 444 | MNTH_XANCP Probable manganese transport prote... | 456 | 3e-45 | 170 | 36 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | P51027 | 555 | NRAM1_CHICK Natural resistance-associated mac... | 461 | 7e-42 | 162 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IMP:BHF-UCL. | | | | | | | | | | GO:0051139; F:metal ion:hydrogen antiporter activity; IGI:BHF-UCL.::GO:0046915; F:transition metal ion transmembrane transporter activity; IGI:BHF-UCL. | | | | | | | | | | GO:0070574; P:cadmium ion transmembrane transport; IGI:BHF-UCL.::GO:0006876; P:cellular cadmium ion homeostasis; IGI:BHF-UCL.::GO:0070839; P:divalent metal ion export; ISS:BHF-UCL.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 25 | O77741 | 538 | NRAM1_PIG Natural resistance-associated macro... | 476 | 2e-40 | 158 | 31 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI. | 26 | Q9RTP8 | 436 | MNTH_DEIRA Probable manganese transport prote... | 489 | 3e-40 | 155 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | P49283 | 596 | MVL_DROME Protein Malvolio OS=Drosophila mela... | 462 | 1e-38 | 152 | 30 | 46 | GO:0044444; C:cytoplasmic part; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005375; F:copper ion transmembrane transporter activity; IMP:FlyBase.::GO:0005381; F:iron ion transmembrane transporter activity; IMP:FlyBase.::GO:0005384; F:manganese ion transmembrane transporter activity; IMP:FlyBase.::GO:0015293; F:symporter activity; IGI:FlyBase. | | | | | | | | | | GO:0055070; P:copper ion homeostasis; IMP:FlyBase.::GO:0015677; P:copper ion import; IMP:FlyBase.::GO:0070838; P:divalent metal ion transport; IGI:FlyBase.::GO:0033212; P:iron assimilation; IDA:FlyBase.::GO:0060586; P:multicellular organismal iron ion homeostasis; IDA:FlyBase.::GO:0050916; P:sensory perception of sweet taste; IMP:FlyBase.::GO:0055076; P:transition metal ion homeostasis; IMP:FlyBase.::GO:0046718; P:viral entry into host cell; IMP:FlyBase. | 28 | P56436 | 548 | NRAM1_CEREL Natural resistance-associated mac... | 460 | 2e-38 | 152 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 29 | P49279 | 550 | NRAM1_HUMAN Natural resistance-associated mac... | 467 | 3e-38 | 151 | 32 | 47 | GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031902; C:late endosome membrane; TAS:Reactome.::GO:0005764; C:lysosome; ISS:BHF-UCL.::GO:0030670; C:phagocytic vesicle membrane; IDA:BHF-UCL.::GO:0070821; C:tertiary granule membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005384; F:manganese ion transmembrane transporter activity; ISS:BHF-UCL.::GO:0051139; F:metal ion:hydrogen antiporter activity; IGI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; ISS:BHF-UCL.::GO:0048002; P:antigen processing and presentation of peptide antigen; ISS:BHF-UCL.::GO:0070574; P:cadmium ion transmembrane transport; IGI:BHF-UCL.::GO:0006876; P:cellular cadmium ion homeostasis; IGI:BHF-UCL.::GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.::GO:0050829; P:defense response to Gram-negative bacterium; ISS:BHF-UCL.::GO:0042832; P:defense response to protozoan; ISS:BHF-UCL.::GO:0070839; P:divalent metal ion export; ISS:BHF-UCL.::GO:0006954; P:inflammatory response; ISS:BHF-UCL.::GO:0032623; P:interleukin-2 production; ISS:BHF-UCL.::GO:0032632; P:interleukin-3 production; ISS:BHF-UCL.::GO:0006826; P:iron ion transport; IMP:BHF-UCL.::GO:0043091; P:L-arginine import; ISS:BHF-UCL.::GO:0042116; P:macrophage activation; ISS:BHF-UCL.::GO:0045342; P:MHC class II biosynthetic process; ISS:BHF-UCL.::GO:0048255; P:mRNA stabilization; ISS:BHF-UCL.::GO:0060586; P:multicellular organismal iron ion homeostasis; ISS:BHF-UCL.::GO:0001818; P:negative regulation of cytokine production; ISS:BHF-UCL.::GO:0015707; P:nitrite transport; ISS:BHF-UCL.::GO:0006909; P:phagocytosis; ISS:BHF-UCL.::GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.::GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0050766; P:positive regulation of phagocytosis; ISS:BHF-UCL.::GO:0002827; P:positive regulation of T-helper 1 type immune response; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0045730; P:respiratory burst; ISS:BHF-UCL.::GO:0034341; P:response to interferon-gamma; ISS:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.::GO:0002369; P:T cell cytokine production; ISS:BHF-UCL.::GO:0002309; P:T cell proliferation involved in immune response; ISS:BHF-UCL.::GO:0007035; P:vacuolar acidification; ISS:BHF-UCL.::GO:0042060; P:wound healing; ISS:BHF-UCL. | 30 | Q95102 | 548 | NRAM1_BISBI Natural resistance-associated mac... | 462 | 4e-38 | 151 | 31 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. | 31 | P41251 | 548 | NRAM1_MOUSE Natural resistance-associated mac... | 528 | 8e-38 | 150 | 29 | 44 | GO:0009279; C:cell outer membrane; IDA:MGI.::GO:0010008; C:endosome membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:MGI.::GO:0030670; C:phagocytic vesicle membrane; IDA:MGI.::GO:0005773; C:vacuole; IMP:GOC. | | | | | | | | | | GO:0005384; F:manganese ion transmembrane transporter activity; IMP:MGI. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; IMP:MGI.::GO:0048002; P:antigen processing and presentation of peptide antigen; IMP:MGI.::GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0050829; P:defense response to Gram-negative bacterium; IMP:MGI.::GO:0042832; P:defense response to protozoan; IMP:MGI.::GO:0070839; P:divalent metal ion export; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0032623; P:interleukin-2 production; IMP:MGI.::GO:0032632; P:interleukin-3 production; IMP:MGI.::GO:0006826; P:iron ion transport; IMP:MGI.::GO:0043091; P:L-arginine import; IDA:MGI.::GO:0042116; P:macrophage activation; IDA:MGI.::GO:0045342; P:MHC class II biosynthetic process; IMP:MGI.::GO:0048255; P:mRNA stabilization; IMP:MGI.::GO:0060586; P:multicellular organismal iron ion homeostasis; IMP:MGI.::GO:0001818; P:negative regulation of cytokine production; IMP:MGI.::GO:0015707; P:nitrite transport; IDA:MGI.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0032729; P:positive regulation of interferon-gamma production; IMP:MGI.::GO:0050766; P:positive regulation of phagocytosis; IMP:MGI.::GO:0002827; P:positive regulation of T-helper 1 type immune response; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0000060; P:protein import into nucleus, translocation; IMP:MGI.::GO:0045730; P:respiratory burst; IDA:MGI.::GO:0034341; P:response to interferon-gamma; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0002369; P:T cell cytokine production; IMP:MGI.::GO:0002309; P:T cell proliferation involved in immune response; IMP:MGI.::GO:0007035; P:vacuolar acidification; IMP:MGI.::GO:0042060; P:wound healing; IMP:MGI. |