| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | P00797 | 406 | RENI_HUMAN Renin OS=Homo sapiens (Human). GN=... | 332 | 3e-19 | 93.2 | 25 | 45 | GO:0005615; C:extracellular space; IDA:HGNC.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:HGNC. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IDA:HGNC.::GO:0006508; P:proteolysis; IDA:HGNC.::GO:0043408; P:regulation of MAPK cascade; IDA:HGNC. | 92 | O13340 | 425 | CARP_PODAS Podosporapepsin OS=Podospora anser... | 319 | 4e-19 | 92.8 | 27 | 45 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 93 | P09177 | 427 | CARP_RHIPU Mucorpepsin OS=Rhizomucor pusillus... | 353 | 6e-19 | 92.4 | 28 | 45 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 94 | B6HL60 | 396 | PEPA_PENCW Aspartic protease pep1 OS=54-1255)... | 345 | 3e-18 | 89.7 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 95 | O04057 | 513 | ASPR_CUCPE Aspartic proteinase OS=Cucurbita p... | 250 | 4e-18 | 90.5 | 30 | 50 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 96 | P00793 | 367 | PEPA_CHICK Pepsin A OS=Gallus gallus (Chicken... | 219 | 7e-18 | 88.6 | 25 | 51 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 97 | Q03699 | 391 | CARP3_RHINI Rhizopuspepsin-3 OS=Rhizopus nive... | 322 | 7e-18 | 88.6 | 28 | 46 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 98 | P08424 | 402 | RENI_RAT Renin OS=Rattus norvegicus (Rat). GN... | 344 | 1e-17 | 88.2 | 24 | 41 | GO:0044444; C:cytoplasmic part; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:RGD. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0070305; P:response to cGMP; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0006950; P:response to stress; IDA:RGD. | 99 | P78735 | 394 | PEPA_PENJA Aspartic protease pepA OS=Penicill... | 341 | 1e-17 | 88.2 | 28 | 46 | GO:0005576; C:extracellular region; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 100 | P43231 | 391 | CARP2_RHINI Rhizopuspepsin-2 OS=Rhizopus nive... | 324 | 2e-17 | 87.8 | 28 | 45 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 101 | P55956 | 398 | ASP3_CAEEL Aspartic protease 3 OS=Caenorhabdi... | 339 | 2e-17 | 87.8 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 102 | P11838 | 419 | CARP_CRYPA Endothiapepsin OS=parasitica). GN=... | 322 | 3e-17 | 87.4 | 30 | 45 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 103 | O93885 | 386 | PEPA_EMENI Aspartic protease pep1 OS=194 / M1... | 406 | 4e-17 | 86.3 | 26 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 104 | E5A7T3 | 409 | PEPA_LEPMJ Aspartic protease PEP1 OS=Av1-4-5-... | 318 | 7e-17 | 85.9 | 28 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 105 | Q12567 | 394 | PEPA_ASPSA Aspartic protease pep1 OS=Aspergil... | 343 | 9e-17 | 85.5 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 106 | Q9Y5Z0 | 518 | BACE2_HUMAN Beta-secretase 2 OS=Homo sapiens ... | 260 | 2e-16 | 85.5 | 25 | 47 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; IMP:UniProtKB.::GO:0016486; P:peptide hormone processing; NAS:UniProtKB. | 107 | Q9JL18 | 514 | BACE2_MOUSE Beta-secretase 2 OS=Mus musculus ... | 278 | 3e-16 | 84.7 | 24 | 46 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB. | 108 | Q4WZS3 | 428 | Y5950_ASPFU Putative aspergillopepsin A-like ... | 325 | 3e-16 | 84 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 109 | P00799 | 430 | CARP_RHIMI Mucorpepsin OS=Rhizomucor miehei. ... | 279 | 4e-16 | 84 | 25 | 42 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 110 | Q4WFS2 | 439 | Y1220_ASPFU Probable aspartic-type endopeptid... | 366 | 4e-16 | 84 | 27 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 111 | Q6IE75 | 514 | BACE2_RAT Beta-secretase 2 OS=Rattus norvegic... | 260 | 4e-16 | 84.3 | 24 | 46 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB. | 112 | P55325 | 394 | PEPA_ASPNG Aspartic protease pep1 OS=Aspergil... | 343 | 5e-16 | 83.2 | 27 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 113 | A2R3L3 | 394 | PEPA_ASPNC Aspartic protease pep1 OS=Aspergil... | 343 | 8e-16 | 82.8 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 114 | P06281 | 402 | RENI1_MOUSE Renin-1 OS=Mus musculus (Mouse). ... | 346 | 8e-16 | 82.8 | 25 | 41 | GO:0005615; C:extracellular space; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IMP:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0042756; P:drinking behavior; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0001823; P:mesonephros development; IEP:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0002018; P:renin-angiotensin regulation of aldosterone production; IDA:MGI. | 115 | P00798 | 323 | PENP_PENJA Penicillopepsin OS=Penicillium jan... | 341 | 8e-16 | 81.6 | 28 | 43 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 116 | Q9HEZ3 | 394 | PEPB_PENJA Aspartic protease pepB OS=Penicill... | 340 | 8e-16 | 82.8 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 117 | P10602 | 389 | CARP1_RHINI Rhizopuspepsin-1 OS=Rhizopus nive... | 325 | 9e-16 | 82.4 | 30 | 47 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 118 | D4DGR1 | 430 | Y6366_TRIVH Probable aspartic-type endopeptid... | 324 | 0.000000000000001 | 82.4 | 27 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 119 | O01530 | 389 | ASP6_CAEEL Aspartic protease 6 OS=Caenorhabdi... | 343 | 0.000000000000001 | 82 | 25 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 120 | P43232 | 392 | CARP5_RHINI Rhizopuspepsin-5 OS=Rhizopus nive... | 321 | 0.000000000000001 | 82 | 26 | 45 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 121 | P41748 | 395 | PEPA_ASPFU Aspartic protease pep1 OS=A1100) (... | 335 | 0.000000000000002 | 81.6 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
