| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | A2R5J1 | 1270 | MYO1_ASPNC Myosin-1 OS=Aspergillus niger (str... | 34 | 2.4 | 33.1 | 32 | 65 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 572 | A1DBH2 | 1250 | MYO1_NEOFI Myosin-1 OS=181) (Aspergillus fisc... | 52 | 2.5 | 33.1 | 29 | 54 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 573 | Q80YF9 | 1305 | RHG33_MOUSE Rho GTPase-activating protein 33 ... | 60 | 2.7 | 33.1 | 28 | 52 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 574 | O42287 | 1270 | ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (... | 71 | 3 | 33.1 | 31 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 575 | A1X283 | 911 | SPD2B_HUMAN SH3 and PX domain-containing prot... | 57 | 3.1 | 32.7 | 28 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 576 | Q8CG79 | 1128 | ASPP2_MOUSE Apoptosis-stimulating of p53 prot... | 51 | 3.1 | 33.1 | 29 | 53 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; IMP:MGI.::GO:0009792; P:embryo development ending in birth or egg hatching; IGI:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:MGI. | 577 | A6QQZ7 | 576 | MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bo... | 40 | 3.2 | 32.7 | 35 | 60 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 578 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 56 | 3.7 | 32.7 | 30 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. | 579 | O43639 | 380 | NCK2_HUMAN Cytoplasmic protein NCK2 OS=Homo s... | 50 | 3.7 | 32.3 | 26 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB. | 580 | O75791 | 330 | GRAP2_HUMAN GRB2-related adapter protein 2 OS... | 44 | 3.8 | 32.3 | 36 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 581 | Q1LYG0 | 1119 | SPD2A_DANRE SH3 and PX domain-containing prot... | 93 | 3.9 | 32.7 | 26 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 582 | O89100 | 322 | GRAP2_MOUSE GRB2-related adaptor protein 2 OS... | 44 | 4 | 32.3 | 34 | 59 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 583 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 40 | 4 | 32.7 | 28 | 65 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 584 | Q8NFA2 | 376 | NOXO1_HUMAN NADPH oxidase organizer 1 OS=Homo... | 46 | 4 | 32.3 | 26 | 48 | GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; TAS:BHF-UCL. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; TAS:BHF-UCL. | 585 | P38822 | 633 | BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere... | 54 | 4.1 | 32.3 | 28 | 52 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD. | 586 | P42685 | 505 | FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo... | 57 | 4.1 | 32.3 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 587 | P49697 | 467 | EM55_TAKRU 55 kDa erythrocyte membrane protei... | 34 | 4.2 | 32.3 | 32 | 59 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 588 | Q5U2Y3 | 576 | MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt... | 41 | 4.3 | 32.3 | 32 | 59 | GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 589 | A1C4A5 | 1253 | MYO1_ASPCL Myosin-1 OS=3887 / NRRL 1). GN=myo... | 31 | 4.3 | 32.3 | 35 | 68 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 590 | O89032 | 1124 | SPD2A_MOUSE SH3 and PX domain-containing prot... | 40 | 4.4 | 32.3 | 28 | 65 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 591 | Q8AXQ3 | 966 | SH3B4_SERQU SH3 domain-binding protein 4 OS=S... | 41 | 4.6 | 32.3 | 29 | 51 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 592 | Q5T2T1 | 576 | MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Ho... | 40 | 5.2 | 32 | 33 | 60 | GO:0097025; C:MPP7-DLG1-LIN7 complex; IDA:BHF-UCL.::GO:0005923; C:tight junction; IDA:BHF-UCL. | | | | | | | | | | GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0035591; F:signaling adaptor activity; NAS:BHF-UCL. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; TAS:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.::GO:0070830; P:tight junction assembly; IDA:BHF-UCL. | 593 | Q1LVQ2 | 965 | SH34A_DANRE SH3 domain-binding protein 4-A OS... | 41 | 5.4 | 32 | 27 | 54 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 594 | Q28GP7 | 549 | SNX33_XENTR Sorting nexin-33 OS=Xenopus tropi... | 67 | 5.4 | 32 | 27 | 63 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 595 | Q922K9 | 512 | FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus ... | 57 | 5.4 | 32 | 28 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 596 | A8KBF6 | 576 | MPP7_XENTR MAGUK p55 subfamily member 7 OS=Xe... | 40 | 5.6 | 32 | 33 | 60 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 597 | Q7TNF8 | 1846 | RIMB1_MOUSE Peripheral-type benzodiazepine re... | 59 | 5.9 | 32 | 29 | 54 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 598 | Q75JD4 | 533 | Y1676_DICDI SH3 and FCH domain-containing pro... | 54 | 6 | 32 | 28 | 56 | | | | | | | | | | | | | | | | | | | | | | 599 | Q24210 | 898 | CSKP_DROME Peripheral plasma membrane protein... | 54 | 6 | 32 | 24 | 57 | GO:0031594; C:neuromuscular junction; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0061174; C:type I terminal button; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:FlyBase.::GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007163; P:establishment or maintenance of cell polarity; NAS:FlyBase.::GO:0040011; P:locomotion; IMP:BHF-UCL.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:BHF-UCL.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IDA:FlyBase.::GO:2000331; P:regulation of terminal button organization; IMP:BHF-UCL.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; NAS:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; NAS:FlyBase. | 600 | Q08509 | 821 | EPS8_MOUSE Epidermal growth factor receptor k... | 55 | 6 | 32 | 27 | 60 | GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:MGI.::GO:0051017; P:actin filament bundle assembly; IGI:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0048149; P:behavioral response to ethanol; IMP:MGI. | 601 | O55033 | 380 | NCK2_MOUSE Cytoplasmic protein NCK2 OS=Mus mu... | 50 | 6.2 | 31.6 | 24 | 56 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. |
