rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
481 | Q6DD51 | 1205 | CSKI2_XENLA Caskin-2 OS=Xenopus laevis (Afric... | 76 | 0.36 | 35.8 | 32 | 50 | | | | | | | | | | | | | | | | | | | | | | 482 | Q15642 | 601 | CIP4_HUMAN Cdc42-interacting protein 4 OS=Hom... | 50 | 0.37 | 35.8 | 32 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 483 | Q5ZJ00 | 468 | EM55_CHICK 55 kDa erythrocyte membrane protei... | 29 | 0.38 | 35.4 | 41 | 69 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 484 | Q5RCJ1 | 601 | CIP4_PONAB Cdc42-interacting protein 4 OS=Pon... | 50 | 0.38 | 35.8 | 32 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 485 | Q86WN1 | 690 | FCSD1_HUMAN FCH and double SH3 domains protei... | 77 | 0.39 | 35.8 | 27 | 47 | | | | | | | | | | | | | | | | | | | | | | 486 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 71 | 0.4 | 35.8 | 25 | 51 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 487 | Q8BZT2 | 735 | SH3R2_MOUSE Putative E3 ubiquitin-protein lig... | 50 | 0.41 | 35.4 | 30 | 56 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 488 | Q8CJ53 | 603 | CIP4_MOUSE Cdc42-interacting protein 4 OS=Mus... | 50 | 0.41 | 35.4 | 32 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; TAS:MGI.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 489 | O74653 | 871 | POB1_SCHPO Protein pob1 OS=Schizosaccharomyce... | 55 | 0.43 | 35.4 | 36 | 56 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase. | 490 | O08839 | 588 | BIN1_RAT Myc box-dependent-interacting protei... | 101 | 0.46 | 35.4 | 27 | 43 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0044300; C:cerebellar mossy fiber; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043196; C:varicosity; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; IMP:RGD.::GO:0043547; P:positive regulation of GTPase activity; IDA:RGD. | 491 | Q7SGL6 | 304 | SHO1_NEUCR High osmolarity signaling protein ... | 54 | 0.47 | 35 | 31 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 492 | Q6DII7 | 345 | SKAP1_XENTR Src kinase-associated phosphoprot... | 51 | 0.48 | 35 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 493 | Q6FTC4 | 353 | SHO1_CANGA High osmolarity signaling protein ... | 59 | 0.51 | 35 | 27 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 494 | Q6YKA8 | 211 | DRK_DROSI Protein E(sev)2B OS=Drosophila simu... | 41 | 0.52 | 34.7 | 27 | 71 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 495 | Q08012 | 211 | DRK_DROME Protein enhancer of sevenless 2B OS... | 41 | 0.52 | 34.7 | 27 | 71 | GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase. | 496 | C7Z504 | 295 | SHO1_NECH7 High osmolarity signaling protein ... | 54 | 0.52 | 35 | 30 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 497 | Q6PG29 | 341 | SKAP2_DANRE Src kinase-associated phosphoprot... | 100 | 0.52 | 35 | 26 | 34 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 498 | D6PVB5 | 320 | SHO1B_HORWE High osmolarity signaling protein... | 54 | 0.55 | 35 | 28 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 499 | O08539 | 588 | BIN1_MOUSE Myc box-dependent-interacting prot... | 75 | 0.58 | 35 | 27 | 45 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042692; P:muscle cell differentiation; IMP:MGI. | 500 | Q9P7E8 | 857 | APP1_SCHPO Protein app1 OS=Schizosaccharomyce... | 46 | 0.59 | 35 | 39 | 59 | GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IC:PomBase. | 501 | D6PVB4 | 321 | SHO1A_HORWE High osmolarity signaling protein... | 54 | 0.61 | 34.7 | 28 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 502 | Q4WUG9 | 288 | SHO1_ASPFU High osmolarity signaling protein ... | 54 | 0.62 | 34.7 | 28 | 65 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 503 | B0Y3Z4 | 288 | SHO1_ASPFC High osmolarity signaling protein ... | 54 | 0.62 | 34.7 | 28 | 65 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 504 | Q71F54 | 894 | SH3R1_RAT E3 ubiquitin-protein ligase SH3RF1 ... | 72 | 0.65 | 35 | 28 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006917; P:induction of apoptosis; IMP:RGD. | 505 | E6RET3 | 296 | SHO1_CRYGW High osmolarity signaling protein ... | 54 | 0.66 | 34.7 | 35 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 506 | Q69ZI1 | 892 | SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF... | 72 | 0.67 | 35 | 28 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046328; P:regulation of JNK cascade; IDA:MGI. | 507 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 49 | 0.69 | 34.3 | 27 | 59 | | | | | | | | | | | | | | | | | | | | | | 508 | Q0CEX5 | 1246 | MYO1_ASPTN Myosin-1 OS=Aspergillus terreus (s... | 56 | 0.69 | 35 | 32 | 54 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 509 | Q5RBR0 | 888 | SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF... | 72 | 0.7 | 35 | 28 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 510 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 72 | 0.7 | 35 | 28 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 511 | Q9QX74 | 1474 | SHAN2_RAT SH3 and multiple ankyrin repeat dom... | 59 | 0.7 | 35 | 27 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD. |