rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | P34416 | 335 | LASP1_CAEEL LIM and SH3 domain protein F42H10... | 52 | 0.043 | 38.5 | 31 | 62 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 422 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 80 | 0.044 | 38.5 | 28 | 55 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 423 | P41240 | 450 | CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo... | 64 | 0.045 | 38.5 | 38 | 52 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005886; C:plasma membrane; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 424 | P41241 | 450 | CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ... | 64 | 0.047 | 38.5 | 38 | 52 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC. | 425 | Q0VBZ0 | 450 | CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos ... | 64 | 0.047 | 38.5 | 38 | 52 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 426 | Q5RC07 | 716 | ES8L2_PONAB Epidermal growth factor receptor ... | 80 | 0.051 | 38.5 | 28 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 427 | Q07840 | 426 | EM13_ECHMU Antigen EM13 OS=Echinococcus multi... | 46 | 0.053 | 38.1 | 39 | 59 | | | | | | | | | | | | | | | | | | | | | | 428 | Q920G0 | 358 | SKAP2_RAT Src kinase-associated phosphoprotei... | 56 | 0.054 | 38.1 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 429 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 46 | 0.055 | 38.1 | 39 | 59 | | | | | | | | | | | | | | | | | | | | | | 430 | P34258 | 493 | YKA7_CAEEL Uncharacterized protein B0303.7 OS... | 38 | 0.056 | 38.1 | 39 | 58 | | | | | | | | | | | | | | | | | | | | | | 431 | P08103 | 524 | HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus ... | 53 | 0.058 | 38.1 | 32 | 58 | GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; IGI:MGI.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IMP:MGI.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB. | 432 | Q3UND0 | 358 | SKAP2_MOUSE Src kinase-associated phosphoprot... | 56 | 0.058 | 38.1 | 34 | 52 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI. | 433 | Q8WXE0 | 1202 | CSKI2_HUMAN Caskin-2 OS=Homo sapiens (Human).... | 113 | 0.066 | 38.1 | 29 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 434 | E5AD87 | 336 | SHO1_LEPMJ High osmolarity signaling protein ... | 62 | 0.068 | 37.7 | 31 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 435 | Q9UFD9 | 1639 | RIM3A_HUMAN RIMS-binding protein 3A OS=Homo s... | 47 | 0.069 | 38.1 | 43 | 66 | | | | | | | | | | | | | | | | | | | | | | 436 | A6NJZ7 | 1639 | RIM3C_HUMAN RIMS-binding protein 3C OS=Homo s... | 47 | 0.072 | 38.1 | 43 | 66 | | | | | | | | | | | | | | | | | | | | | | 437 | A6NNM3 | 1639 | RIM3B_HUMAN RIMS-binding protein 3B OS=Homo s... | 47 | 0.073 | 38.1 | 43 | 66 | | | | | | | | | | | | | | | | | | | | | | 438 | Q498M5 | 735 | SH3R2_RAT Putative E3 ubiquitin-protein ligas... | 57 | 0.081 | 37.7 | 30 | 53 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 439 | C5MB30 | 340 | SHO1_CANTT High osmolarity signaling protein ... | 57 | 0.086 | 37.4 | 30 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 440 | A5E1V8 | 324 | SHO1_LODEL High osmolarity signaling protein ... | 57 | 0.088 | 37.4 | 30 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 441 | Q6BVC2 | 304 | SHO1_DEBHA High osmolarity signaling protein ... | 55 | 0.09 | 37.4 | 31 | 69 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 442 | Q10199 | 670 | IMP2_SCHPO Septation protein imp2 OS=Schizosa... | 56 | 0.092 | 37.7 | 30 | 55 | GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 443 | A7TI28 | 358 | SHO1_VANPO High osmolarity signaling protein ... | 58 | 0.1 | 37.4 | 31 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 444 | Q9P2A4 | 366 | ABI3_HUMAN ABI gene family member 3 OS=Homo s... | 48 | 0.1 | 37.4 | 33 | 54 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:MGI. | 445 | P46109 | 303 | CRKL_HUMAN Crk-like protein OS=Homo sapiens (... | 45 | 0.11 | 37 | 36 | 62 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 446 | Q45FX5 | 1007 | VAV_CAEEL Protein vav-1 OS=Caenorhabditis ele... | 39 | 0.11 | 37.4 | 36 | 64 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 447 | C4YDC4 | 385 | SHO1_CANAW High osmolarity signaling protein ... | 57 | 0.11 | 37.4 | 30 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 448 | Q5AQ36 | 387 | SHO1_CANAL High osmolarity signaling protein ... | 57 | 0.11 | 37.4 | 30 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0000902; P:cell morphogenesis; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:CGD.::GO:0090033; P:positive regulation of filamentous growth; IMP:CGD. | 449 | P31693 | 523 | SRC_RSVPA Tyrosine-protein kinase transformin... | 41 | 0.11 | 37.4 | 39 | 59 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 450 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 45 | 0.12 | 37 | 36 | 62 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 451 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 45 | 0.12 | 37 | 36 | 62 | | | | | | | | | | | | | | | | | | | | | |