| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | P42522 | 1182 | MYOC_DICDI Myosin IC heavy chain OS=Dictyoste... | 53 | 0.0004 | 45.1 | 34 | 62 | GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IMP:dictyBase. | 242 | O77506 | 263 | LASP1_RABIT LIM and SH3 domain protein 1 OS=O... | 56 | 0.0004 | 44.3 | 38 | 61 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 243 | P08487 | 1291 | PLCG1_BOVIN 1-phosphatidylinositol 4,5-bispho... | 60 | 0.0004 | 45.1 | 32 | 58 | GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; ISS:AgBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB. | 244 | Q9UKS6 | 424 | PACN3_HUMAN Protein kinase C and casein kinas... | 60 | 0.0004 | 44.7 | 38 | 67 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; ISS:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL. | 245 | Q99JB8 | 424 | PACN3_MOUSE Protein kinase C and casein kinas... | 60 | 0.0005 | 44.7 | 38 | 67 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI. | 246 | Q08EC4 | 804 | CASS4_MOUSE Cas scaffolding protein family me... | 71 | 0.0005 | 44.7 | 34 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 247 | Q8JH64 | 657 | BTK_CHICK Tyrosine-protein kinase BTK OS=Gall... | 89 | 0.0005 | 44.7 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 248 | Q6TGW5 | 214 | OSTF1_DANRE Osteoclast-stimulating factor 1 O... | 49 | 0.0006 | 43.5 | 35 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 249 | Q7T2V3 | 1005 | M3K10_XENLA Mitogen-activated protein kinase ... | 44 | 0.0006 | 44.7 | 39 | 73 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0071570; P:cement gland development; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB. | 250 | Q6XJU9 | 214 | OSTF1_MONAL Osteoclast-stimulating factor 1 O... | 65 | 0.0006 | 43.5 | 31 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 251 | Q8IZP0 | 508 | ABI1_HUMAN Abl interactor 1 OS=Homo sapiens (... | 51 | 0.0006 | 44.3 | 31 | 61 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0006928; P:cellular component movement; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 252 | P19174 | 1290 | PLCG1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 60 | 0.0006 | 44.7 | 32 | 58 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 253 | P51451 | 505 | BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo... | 54 | 0.0006 | 44.3 | 33 | 69 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB. | 254 | Q9JLQ0 | 637 | CD2AP_MOUSE CD2-associated protein OS=Mus mus... | 51 | 0.0007 | 44.3 | 37 | 67 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 255 | Q5HYK7 | 790 | SH319_HUMAN SH3 domain-containing protein 19 ... | 55 | 0.0007 | 44.3 | 31 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:BHF-UCL. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 256 | Q14247 | 550 | SRC8_HUMAN Src substrate cortactin OS=Homo sa... | 51 | 0.0007 | 44.3 | 37 | 57 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:ProtInc.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 257 | Q60598 | 546 | SRC8_MOUSE Src substrate cortactin OS=Mus mus... | 51 | 0.0008 | 43.9 | 37 | 57 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 258 | O35413 | 1196 | SRBS2_RAT Sorbin and SH3 domain-containing pr... | 54 | 0.0009 | 44.3 | 30 | 67 | GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 259 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 50 | 0.0009 | 43.9 | 38 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 260 | Q02977 | 536 | YRK_CHICK Proto-oncogene tyrosine-protein kin... | 70 | 0.0009 | 43.9 | 36 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 261 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 83 | 0.0009 | 43.5 | 34 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 262 | Q3UTJ2 | 1180 | SRBS2_MOUSE Sorbin and SH3 domain-containing ... | 54 | 0.001 | 43.9 | 30 | 67 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 263 | O94875 | 1100 | SRBS2_HUMAN Sorbin and SH3 domain-containing ... | 56 | 0.001 | 43.5 | 30 | 66 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 264 | Q9R1Z8 | 733 | VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ... | 86 | 0.001 | 43.5 | 30 | 53 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:MGI. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI. | 265 | O60504 | 671 | VINEX_HUMAN Vinexin OS=Homo sapiens (Human). ... | 104 | 0.001 | 43.1 | 29 | 54 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0017166; F:vinculin binding; IPI:UniProtKB. | | | | | | | | | | GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB. | 266 | Q62417 | 1290 | SRBS1_MOUSE Sorbin and SH3 domain-containing ... | 56 | 0.001 | 43.9 | 30 | 66 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.::GO:0015758; P:glucose transport; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0043149; P:stress fiber assembly; IDA:UniProtKB. | 267 | Q9BX66 | 1292 | SRBS1_HUMAN Sorbin and SH3 domain-containing ... | 54 | 0.001 | 43.9 | 28 | 69 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.::GO:0005915; C:zonula adherens; TAS:ProtInc. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; ISS:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:BHF-UCL.::GO:0043149; P:stress fiber assembly; ISS:UniProtKB. | 268 | E7A253 | 343 | SHO1_SPORE High osmolarity signaling protein ... | 57 | 0.001 | 43.5 | 35 | 68 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 269 | P00527 | 528 | YES_AVISY Tyrosine-protein kinase transformin... | 50 | 0.001 | 43.9 | 38 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 270 | O43281 | 561 | EFS_HUMAN Embryonal Fyn-associated substrate ... | 93 | 0.001 | 43.9 | 31 | 48 | GO:0005737; C:cytoplasm; TAS:ProtInc. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc. | 271 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 76 | 0.001 | 43.5 | 33 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. |
