| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q8C0D4 | 838 | RHG12_MOUSE Rho GTPase-activating protein 12 ... | 153 | 0.000000001 | 64.3 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 92 | Q8R5G7 | 1538 | ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 176 | 0.000000001 | 64.3 | 24 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 93 | O94988 | 1023 | FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H... | 157 | 0.000000001 | 63.9 | 29 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 94 | Q811P8 | 2089 | RHG32_MOUSE Rho GTPase-activating protein 32 ... | 197 | 0.000000001 | 64.3 | 25 | 49 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 95 | Q6AYC5 | 482 | RHG15_RAT Rho GTPase-activating protein 15 OS... | 179 | 0.000000001 | 63.5 | 24 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 96 | O74360 | 933 | RGA4_SCHPO Probable Rho-type GTPase-activatin... | 176 | 0.000000002 | 63.9 | 24 | 48 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070650; P:actin filament bundle distribution; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IMP:PomBase.::GO:0032231; P:regulation of actin filament bundle assembly; IMP:PomBase.::GO:0060305; P:regulation of cell diameter; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 97 | Q9PT60 | 655 | RBP1A_XENLA RalA-binding protein 1-A OS=Xenop... | 213 | 0.000000002 | 63.5 | 22 | 45 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB. | 98 | P52757 | 468 | CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu... | 180 | 0.000000002 | 63.2 | 24 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 99 | Q53QZ3 | 475 | RHG15_HUMAN Rho GTPase-activating protein 15 ... | 151 | 0.000000002 | 63.2 | 26 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 100 | Q9P2F6 | 1191 | RHG20_HUMAN Rho GTPase-activating protein 20 ... | 168 | 0.000000002 | 63.5 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 101 | Q9R0Z9 | 1092 | RHG07_MOUSE Rho GTPase-activating protein 7 O... | 182 | 0.000000002 | 63.5 | 25 | 46 | GO:0005737; C:cytoplasm; NAS:UniProtKB. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0021575; P:hindbrain morphogenesis; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 102 | Q8BRH3 | 494 | RHG19_MOUSE Rho GTPase-activating protein 19 ... | 193 | 0.000000002 | 63.2 | 31 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 103 | O43295 | 1099 | SRGP3_HUMAN SLIT-ROBO Rho GTPase-activating p... | 179 | 0.000000002 | 63.5 | 24 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 104 | Q63744 | 1091 | RHG07_RAT Rho GTPase-activating protein 7 OS=... | 182 | 0.000000002 | 63.5 | 25 | 46 | GO:0005737; C:cytoplasm; NAS:UniProtKB. | | | | | | | | | | GO:0043274; F:phospholipase binding; IPI:RGD.::GO:0005100; F:Rho GTPase activator activity; IDA:RGD.::GO:0017166; F:vinculin binding; IPI:RGD. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IDA:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; NAS:RGD. | 105 | Q6IFT4 | 1182 | RHG20_MOUSE Rho GTPase-activating protein 20 ... | 167 | 0.000000002 | 63.5 | 28 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 106 | Q6ZQ82 | 814 | RHG26_MOUSE Rho GTPase-activating protein 26 ... | 180 | 0.000000003 | 63.2 | 24 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 107 | Q5F3G0 | 495 | RHG19_CHICK Rho GTPase-activating protein 19 ... | 151 | 0.000000003 | 62.8 | 34 | 55 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 108 | P97393 | 1501 | RHG05_MOUSE Rho GTPase-activating protein 5 O... | 183 | 0.000000003 | 63.2 | 25 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0008361; P:regulation of cell size; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 109 | Q80XD1 | 332 | CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo... | 180 | 0.000000003 | 62 | 23 | 47 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 110 | O14014 | 969 | RGA3_SCHPO Probable Rho-type GTPase-activatin... | 191 | 0.000000004 | 62.8 | 25 | 48 | GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 111 | Q54BF1 | 1132 | GACE_DICDI Rho GTPase-activating protein gacE... | 246 | 0.000000004 | 62.8 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 112 | Q13017 | 1502 | RHG05_HUMAN Rho GTPase-activating protein 5 O... | 183 | 0.000000004 | 62.8 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 113 | Q03070 | 295 | CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ... | 180 | 0.000000004 | 61.2 | 23 | 47 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 114 | P26450 | 724 | P85A_MOUSE Phosphatidylinositol 3-kinase regu... | 168 | 0.000000004 | 62.4 | 30 | 47 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:MGI.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0034644; P:cellular response to UV; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0001953; P:negative regulation of cell-matrix adhesion; IGI:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IGI:MGI.::GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 115 | A7KAX9 | 2087 | RHG32_HUMAN Rho GTPase-activating protein 32 ... | 191 | 0.000000004 | 62.8 | 24 | 48 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 116 | Q8WWN8 | 1544 | ARAP3_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 176 | 0.000000004 | 62.8 | 24 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB. | 117 | Q7Z6B7 | 1085 | SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p... | 180 | 0.000000004 | 62.4 | 23 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. | 118 | Q07960 | 439 | RHG01_HUMAN Rho GTPase-activating protein 1 O... | 151 | 0.000000005 | 61.6 | 26 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 119 | Q13459 | 2157 | MYO9B_HUMAN Unconventional myosin-IXb OS=Homo... | 156 | 0.000000006 | 62 | 28 | 49 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB. | | | | | | | | | | GO:0030048; P:actin filament-based movement; TAS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; IC:UniProtKB. | 120 | Q3E875 | 376 | RGAP1_ARATH Uncharacterized Rho GTPase-activa... | 206 | 0.000000006 | 61.2 | 25 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 121 | Q5FWK3 | 439 | RHG01_MOUSE Rho GTPase-activating protein 1 O... | 151 | 0.000000006 | 61.2 | 26 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI. | | | | | | | | | | GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |
