| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q06407 | 1009 | RGA2_YEAST Rho-type GTPase-activating protein... | 190 | 0.0000007 | 55.5 | 25 | 46 | GO:0032177; C:cellular bud neck split septin rings; IDA:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 182 | Q4LDD4 | 1452 | ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 178 | 0.0000007 | 55.5 | 24 | 47 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 183 | Q6P4F7 | 1023 | RHGBA_HUMAN Rho GTPase-activating protein 11A... | 210 | 0.000001 | 55.1 | 23 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 184 | Q3KRB8 | 267 | RHGBB_HUMAN Rho GTPase-activating protein 11B... | 203 | 0.000001 | 53.1 | 23 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 185 | Q9DBZ9 | 737 | SYDE1_MOUSE Rho GTPase-activating protein SYD... | 198 | 0.000001 | 54.3 | 26 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 186 | Q54PG5 | 399 | GACC_DICDI Rho GTPase-activating protein gacC... | 137 | 0.000002 | 53.5 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 187 | A7MB27 | 530 | RHG36_BOVIN Rho GTPase-activating protein 36 ... | 162 | 0.000002 | 53.9 | 23 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 188 | Q20498 | 759 | RRC1_CAEEL GTPase-activating protein rrc-1 OS... | 158 | 0.000002 | 53.5 | 23 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 189 | Q54J98 | 563 | GACX_DICDI Rho GTPase-activating protein gacX... | 151 | 0.000003 | 53.1 | 21 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 190 | Q6ZUM4 | 889 | RHG27_HUMAN Rho GTPase-activating protein 27 ... | 176 | 0.000005 | 52.8 | 19 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro. | 191 | O94466 | 695 | RGA7_SCHPO Probable Rho-GTPase-activating pro... | 176 | 0.000006 | 52.4 | 26 | 46 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:PomBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 192 | Q9BRR9 | 750 | RHG09_HUMAN Rho GTPase-activating protein 9 O... | 181 | 0.00002 | 50.8 | 27 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 193 | Q54SL6 | 531 | GACQ_DICDI Rho GTPase-activating protein gacQ... | 152 | 0.00002 | 50.4 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 194 | Q9Y3L3 | 701 | 3BP1_HUMAN SH3 domain-binding protein 1 OS=Ho... | 158 | 0.00002 | 50.4 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 195 | Q6ZRI8 | 547 | RHG36_HUMAN Rho GTPase-activating protein 36 ... | 162 | 0.00002 | 50.4 | 23 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 196 | Q5TG30 | 622 | RHG40_HUMAN Rho GTPase-activating protein 40 ... | 153 | 0.00005 | 49.3 | 24 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 197 | P59281 | 1107 | RHG39_MOUSE Rho GTPase-activating protein 39 ... | 184 | 0.00008 | 48.9 | 24 | 41 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 198 | Q9C0H5 | 1083 | RHG39_HUMAN Rho GTPase-activating protein 39 ... | 184 | 0.00009 | 48.5 | 24 | 40 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 199 | Q9HF75 | 2071 | BEM2_ASHGO GTPase-activating protein BEM2 OS=... | 247 | 0.00009 | 48.9 | 21 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 200 | Q8UUU2 | 722 | P85AA_XENLA Phosphatidylinositol 3-kinase reg... | 149 | 0.0001 | 48.1 | 26 | 47 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB. | 201 | P39083 | 1007 | RGA1_YEAST Rho-type GTPase-activating protein... | 193 | 0.0002 | 47.8 | 23 | 46 | GO:0032177; C:cellular bud neck split septin rings; IDA:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:SGD.::GO:0007118; P:budding cell apical bud growth; IPI:SGD.::GO:0007119; P:budding cell isotropic bud growth; IPI:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IPI:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD.::GO:0007124; P:pseudohyphal growth; IPI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 202 | Q8K337 | 993 | I5P2_MOUSE Type II inositol 1,4,5-trisphospha... | 206 | 0.0002 | 47.4 | 23 | 40 | GO:0005829; C:cytosol; IDA:MGI.::GO:0016021; C:integral to membrane; IDA:MGI. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0070613; P:regulation of protein processing; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 203 | Q01968 | 901 | OCRL_HUMAN Inositol polyphosphate 5-phosphata... | 119 | 0.0003 | 47 | 27 | 49 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; TAS:ProtInc.::GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc. | | | | | | | | | | GO:0004437; F:inositol or phosphatidylinositol phosphatase activity; TAS:ProtInc.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 204 | Q1ZXE1 | 896 | GACM_DICDI Rho GTPase-activating protein gacM... | 122 | 0.0006 | 45.8 | 26 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 205 | P32019 | 993 | I5P2_HUMAN Type II inositol 1,4,5-trisphospha... | 187 | 0.0008 | 45.4 | 22 | 40 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 206 | P46941 | 837 | TG325_CAEEL WW domain-containing protein tag-... | 191 | 0.001 | 45.4 | 19 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 207 | Q9VX32 | 1561 | RG190_DROME Rho GTPase-activating protein 190... | 164 | 0.001 | 45.1 | 21 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 208 | Q54NL0 | 1009 | GACT_DICDI Rho GTPase-activating protein gacT... | 221 | 0.002 | 44.7 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. | 209 | Q55GP8 | 684 | GACO_DICDI Rho GTPase-activating protein gacO... | 133 | 0.003 | 43.9 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 210 | Q54FF4 | 734 | GACL_DICDI Rho GTPase-activating protein gacL... | 225 | 0.003 | 43.5 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 211 | P35688 | 1017 | LRG1_YEAST Rho-GTPase-activating protein LRG1... | 205 | 0.006 | 42.7 | 22 | 45 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009272; P:fungal-type cell wall biogenesis; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. |
