| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | P33886 | 605 | WIS1_SCHPO Protein kinase wis1 OS=Schizosacch... | 148 | 0.0001 | 48.1 | 26 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; TAS:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0043555; P:regulation of translation in response to stress; IMP:PomBase.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; TAS:PomBase. | 332 | P28327 | 561 | RK_BOVIN Rhodopsin kinase OS=Bos taurus (Bovi... | 138 | 0.0001 | 47.8 | 26 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0022400; P:regulation of rhodopsin mediated signaling pathway; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 333 | Q54UL8 | 983 | MPS1_DICDI Probable serine/threonine-protein ... | 152 | 0.0001 | 48.1 | 28 | 46 | GO:0005813; C:centrosome; TAS:dictyBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; ISS:dictyBase. | | | | | | | | | | | 334 | P51617 | 712 | IRAK1_HUMAN Interleukin-1 receptor-associated... | 126 | 0.0001 | 47.8 | 31 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0045323; C:interleukin-1 receptor complex; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004704; F:NF-kappaB-inducing kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:Reactome. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:BHF-UCL.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; NAS:UniProtKB.::GO:0051259; P:protein oligomerization; IMP:UniProtKB.::GO:0001959; P:regulation of cytokine-mediated signaling pathway; IMP:BHF-UCL.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; IMP:BHF-UCL.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; NAS:UniProtKB.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 335 | Q9LMT0 | 391 | CDKD3_ARATH Cyclin-dependent kinase D-3 OS=Ar... | 62 | 0.0001 | 47.4 | 39 | 61 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; TAS:TAIR. | 336 | Q9ST27 | 907 | PHOT2_ORYSJ Phototropin-2 OS=Oryza sativa sub... | 164 | 0.0001 | 48.1 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 337 | Q9LX30 | 1241 | GCN2_ARATH Probable serine/threonine-protein ... | 99 | 0.0001 | 48.1 | 33 | 52 | | | | | | | | | | | GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW. | 338 | Q54R58 | 918 | YTYK2_DICDI Probable tyrosine-protein kinase ... | 154 | 0.0001 | 48.1 | 19 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 339 | P10650 | 346 | MOS_CHLAE Proto-oncogene serine/threonine-pro... | 91 | 0.0001 | 47.4 | 32 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 340 | Q6VZ17 | 626 | HUNKB_XENLA Hormonally up-regulated neu tumor... | 154 | 0.0001 | 47.8 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 341 | Q9SJ61 | 520 | CDPKP_ARATH Calcium-dependent protein kinase ... | 147 | 0.0001 | 47.8 | 30 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 342 | Q8MJ44 | 350 | KAPCA_CANFA cAMP-dependent protein kinase cat... | 138 | 0.0001 | 47.4 | 28 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 343 | Q8BG48 | 372 | ST17B_MOUSE Serine/threonine-protein kinase 1... | 147 | 0.0001 | 47.4 | 28 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 344 | Q86I06 | 1123 | NEK3_DICDI Probable serine/threonine-protein ... | 123 | 0.0002 | 47.8 | 24 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 345 | Q7YRC6 | 344 | AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo... | 127 | 0.0002 | 46.6 | 28 | 49 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 346 | Q9ES74 | 302 | NEK7_MOUSE Serine/threonine-protein kinase Ne... | 148 | 0.0002 | 46.6 | 26 | 46 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | | 347 | Q8TDX7 | 302 | NEK7_HUMAN Serine/threonine-protein kinase Ne... | 148 | 0.0002 | 46.6 | 26 | 46 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 348 | Q6DE08 | 361 | AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev... | 137 | 0.0002 | 47.4 | 28 | 46 | | | | | | | | | | | | | | | | | | | | | | 349 | A8WYE4 | 1088 | PAR1_CAEBR Serine/threonine-protein kinase pa... | 147 | 0.0002 | 47.4 | 27 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 350 | Q9TW45 | 1192 | PAR1_CAEEL Serine/threonine-protein kinase pa... | 147 | 0.0002 | 47.4 | 27 | 46 | GO:0005938; C:cell cortex; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0009949; P:polarity specification of anterior/posterior axis; TAS:WormBase.::GO:0040025; P:vulval development; IMP:WormBase. | 351 | Q8N568 | 766 | DCLK2_HUMAN Serine/threonine-protein kinase D... | 152 | 0.0002 | 47.4 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 352 | Q9NRP7 | 1315 | STK36_HUMAN Serine/threonine-protein kinase 3... | 66 | 0.0002 | 47.8 | 33 | 59 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0000287; F:magnesium ion binding; IC:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB. | 353 | P57059 | 783 | SIK1_HUMAN Serine/threonine-protein kinase SI... | 128 | 0.0002 | 47.8 | 25 | 45 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.::GO:0072333; P:signal transduction by p53 class mediator resulting in induction of anoikis; IMP:BHF-UCL. | 354 | B0WAU8 | 761 | PLK4_CULQU Serine/threonine-protein kinase PL... | 129 | 0.0002 | 47.4 | 29 | 48 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 355 | Q16W24 | 769 | PLK4_AEDAE Serine/threonine-protein kinase PL... | 129 | 0.0002 | 47.4 | 28 | 49 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 356 | B4J3F1 | 762 | PLK4_DROGR Serine/threonine-protein kinase PL... | 145 | 0.0002 | 47.8 | 28 | 45 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 357 | O00444 | 970 | PLK4_HUMAN Serine/threonine-protein kinase PL... | 128 | 0.0002 | 47.8 | 27 | 47 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 358 | Q5R9Z7 | 970 | PLK4_PONAB Serine/threonine-protein kinase PL... | 128 | 0.0002 | 47.8 | 27 | 47 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 359 | P51953 | 344 | CDK7_CARAU Cyclin-dependent kinase 7 OS=Caras... | 76 | 0.0002 | 47.4 | 33 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 360 | Q8W490 | 470 | PEPK2_ARATH Serine/threonine-protein kinase P... | 100 | 0.0002 | 47.4 | 34 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 361 | P36887 | 351 | KAPCA_PIG cAMP-dependent protein kinase catal... | 138 | 0.0002 | 47.4 | 28 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | |
