| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P49602 | 561 | CP51_USTMA Lanosterol 14-alpha demethylase OS... | 502 | 0 | 564 | 56 | 71 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 2 | Q09736 | 495 | CP51_SCHPO Lanosterol 14-alpha demethylase er... | 519 | 2e-163 | 481 | 48 | 65 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008398; F:sterol 14-demethylase activity; ISS:PomBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IEP:PomBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 3 | P14263 | 528 | CP51_CANTR Lanosterol 14-alpha demethylase OS... | 517 | 2e-155 | 462 | 45 | 64 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 4 | P10613 | 528 | CP51_CANAL Lanosterol 14-alpha demethylase OS... | 509 | 9e-155 | 460 | 44 | 64 | GO:0016021; C:integral to membrane; IDA:CGD.::GO:0005624; C:membrane fraction; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD. | | | | | | | | | | GO:0008144; F:drug binding; IDA:CGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IDA:CGD. | | | | | | | | | | GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0006696; P:ergosterol biosynthetic process; IGI:CGD.::GO:0001766; P:membrane raft polarization; IMP:CGD. | 5 | O14442 | 524 | CP51_UNCNE Eburicol 14-alpha-demethylase OS=U... | 533 | 8e-154 | 457 | 46 | 63 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 6 | P50859 | 533 | CP51_CANGA Lanosterol 14-alpha demethylase OS... | 532 | 8e-154 | 458 | 44 | 64 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 7 | P10614 | 530 | CP51_YEAST Lanosterol 14-alpha demethylase OS... | 503 | 1e-152 | 455 | 46 | 64 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008398; F:sterol 14-demethylase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 8 | Q759W0 | 529 | CP51_ASHGO Lanosterol 14-alpha demethylase OS... | 528 | 3e-152 | 454 | 45 | 64 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 9 | Q9UVC3 | 512 | CP51_CUNEL Lanosterol 14-alpha demethylase OS... | 514 | 8e-148 | 442 | 43 | 65 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 10 | Q12664 | 515 | CP51_PENIT Eburicol 14-alpha-demethylase OS=P... | 520 | 1e-146 | 439 | 45 | 61 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 11 | Q02315 | 414 | CP51_ISSOR Lanosterol 14-alpha demethylase OS... | 436 | 1e-126 | 384 | 45 | 64 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 12 | Q64654 | 503 | CP51A_RAT Lanosterol 14-alpha demethylase OS=... | 548 | 2e-106 | 335 | 37 | 54 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IDA:RGD. | | | | | | | | | | GO:0033488; P:cholesterol biosynthetic process via 24,25-dihydrolanosterol; IDA:RGD.::GO:0045540; P:regulation of cholesterol biosynthetic process; TAS:RGD. | 13 | O46420 | 503 | CP51A_PIG Lanosterol 14-alpha demethylase OS=... | 497 | 2e-105 | 332 | 39 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 14 | Q5RE72 | 503 | CP51A_PONAB Lanosterol 14-alpha demethylase O... | 527 | 6e-105 | 331 | 38 | 55 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 15 | Q8K0C4 | 503 | CP51A_MOUSE Lanosterol 14-alpha demethylase O... | 496 | 2e-104 | 330 | 39 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; TAS:MGI. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:MGI. | 16 | Q4R8S6 | 503 | CP51A_MACFA Lanosterol 14-alpha demethylase O... | 497 | 3e-104 | 329 | 39 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 17 | Q16850 | 503 | CP51A_HUMAN Lanosterol 14-alpha demethylase O... | 527 | 4e-104 | 329 | 38 | 54 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 18 | Q4PJW3 | 502 | CP51A_BOVIN Lanosterol 14-alpha demethylase O... | 496 | 3e-101 | 322 | 37 | 55 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 19 | Q1ZXH9 | 466 | CP51_DICDI Probable lanosterol 14-alpha demet... | 527 | 9e-85 | 277 | 35 | 52 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 20 | Q9SAA9 | 488 | CP511_ARATH Sterol 14-demethylase OS=Arabidop... | 516 | 1e-75 | 254 | 33 | 49 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; TAS:TAIR. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IMP:TAIR. | 21 | P93846 | 492 | CP51_SORBI Obtusifoliol 14-alpha demethylase ... | 520 | 1e-70 | 240 | 31 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 22 | P93596 | 453 | CP51_WHEAT Obtusifoliol 14-alpha demethylase ... | 491 | 8e-67 | 229 | 31 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 23 | P0A512 | 451 | CP51_MYCTU Lanosterol 14-alpha demethylase OS... | 478 | 1e-60 | 213 | 31 | 49 | GO:0005829; C:cytosol; IDA:MTBBASE. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:MTBBASE.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0008398; F:sterol 14-demethylase activity; IDA:MTBBASE. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 24 | P0A513 | 451 | CP51_MYCBO Lanosterol 14-alpha demethylase OS... | 478 | 1e-60 | 213 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 25 | Q5IZM4 | 452 | CP51_MYCVP Lanosterol 14-alpha demethylase OS... | 478 | 5e-58 | 206 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 26 | Q7Z1V1 | 481 | CP51_TRYCC Sterol 14-alpha demethylase OS=Try... | 509 | 7e-56 | 200 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 27 | O35074 | 501 | PTGIS_MOUSE Prostacyclin synthase OS=Mus musc... | 473 | 3e-23 | 107 | 23 | 44 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB. | 28 | Q949P1 | 467 | ABAH1_ARATH Abscisic acid 8'-hydroxylase 1 OS... | 455 | 1e-22 | 104 | 24 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009687; P:abscisic acid metabolic process; IMP:TAIR.::GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0048838; P:release of seed from dormancy; IMP:TAIR.::GO:0009639; P:response to red or far red light; IEP:TAIR. | 29 | Q9FH76 | 463 | ABAH3_ARATH Abscisic acid 8'-hydroxylase 3 OS... | 483 | 2e-22 | 103 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0046345; P:abscisic acid catabolic process; TAS:TAIR.::GO:0009639; P:response to red or far red light; IEP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR. | 30 | Q0J185 | 500 | ABAH3_ORYSJ Abscisic acid 8'-hydroxylase 3 OS... | 464 | 2e-22 | 103 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 31 | A2Z212 | 500 | ABAH3_ORYSI Abscisic acid 8'-hydroxylase 3 OS... | 464 | 3e-22 | 103 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
