| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | A6T8N3 | 240 | FOLM_KLEP7 Dihydrofolate reductase folM OS=78... | 194 | 0.00002 | 48.5 | 25 | 42 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 422 | Q83RC9 | 240 | FOLM_SHIFL Dihydrofolate reductase folM OS=Sh... | 254 | 0.00002 | 48.5 | 27 | 39 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 423 | Q0T4H1 | 240 | FOLM_SHIF8 Dihydrofolate reductase folM OS=Sh... | 254 | 0.00002 | 48.5 | 27 | 39 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 424 | P50170 | 317 | RDH2_RAT Retinol dehydrogenase 2 OS=Rattus no... | 208 | 0.00002 | 48.9 | 24 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:RGD. | | | | | | | | | | GO:0042573; P:retinoic acid metabolic process; IDA:RGD.::GO:0042572; P:retinol metabolic process; IDA:RGD. | 425 | Q5NVG2 | 300 | DHB11_PONAB Estradiol 17-beta-dehydrogenase 1... | 134 | 0.00002 | 48.5 | 25 | 50 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 426 | O17795 | 315 | STDH2_CAEEL Putative steroid dehydrogenase 2 ... | 210 | 0.00002 | 48.5 | 26 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 427 | Q2KIJ5 | 331 | KDSR_BOVIN 3-ketodihydrosphingosine reductase... | 225 | 0.00003 | 48.5 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 428 | Q7RZR2 | 325 | TSC10_NEUCR 3-ketodihydrosphingosine reductas... | 68 | 0.00003 | 48.5 | 37 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 429 | Q8T197 | 316 | DHRS7_DICDI Dehydrogenase/reductase SDR famil... | 214 | 0.00003 | 48.5 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 430 | Q7Q732 | 317 | DHRS7_ANOGA Dehydrogenase/reductase SDR famil... | 243 | 0.00003 | 48.1 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 431 | A8AGY5 | 240 | FOLM_CITK8 Dihydrofolate reductase folM OS=Ci... | 253 | 0.00003 | 47.8 | 25 | 39 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 432 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 226 | 0.00004 | 47.8 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 433 | Q9R092 | 317 | H17B6_MOUSE 17-beta-hydroxysteroid dehydrogen... | 208 | 0.00004 | 47.8 | 23 | 42 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 434 | O88451 | 316 | RDH7_MOUSE Retinol dehydrogenase 7 OS=Mus mus... | 210 | 0.00005 | 47.8 | 24 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC. | | | | | | | | | | | 435 | Q566S6 | 309 | DRS7B_DANRE Dehydrogenase/reductase SDR famil... | 99 | 0.00005 | 47.8 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 436 | O54753 | 317 | H17B6_RAT 17-beta-hydroxysteroid dehydrogenas... | 208 | 0.00005 | 47.4 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; TAS:RGD. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:RGD. | 437 | O08699 | 266 | PGDH_RAT 15-hydroxyprostaglandin dehydrogenas... | 204 | 0.00005 | 47.4 | 23 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 438 | P40747 | 689 | YUXG_BACSU Uncharacterized oxidoreductase yux... | 268 | 0.00005 | 48.1 | 25 | 39 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 439 | B0D8R3 | 338 | MKAR_LACBS 3-ketoacyl-CoA reductase OS=deceiv... | 211 | 0.00006 | 47.4 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 440 | Q6Q7D1 | 287 | DHI1L_BOVIN Hydroxysteroid 11-beta-dehydrogen... | 93 | 0.00006 | 47.4 | 29 | 58 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 441 | Q4JK73 | 300 | DHB11_MACFA Estradiol 17-beta-dehydrogenase 1... | 134 | 0.00006 | 47.4 | 25 | 50 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 442 | Q6RVV4 | 316 | TIC32_PEA Short-chain dehydrogenase TIC 32, c... | 219 | 0.00008 | 47 | 27 | 43 | GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 443 | Q10245 | 341 | MKAR_SCHPO 3-ketoacyl-CoA reductase OS=Schizo... | 249 | 0.00009 | 47 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045703; F:ketoreductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:PomBase. | 444 | B2WMJ3 | 341 | MKAR_PYRTR 3-ketoacyl-CoA reductase OS=fungus... | 201 | 0.00009 | 47 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 445 | B1LET0 | 240 | FOLM_ECOSM Dihydrofolate reductase folM OS=Es... | 254 | 0.00009 | 46.6 | 27 | 39 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 446 | P95158 | 225 | Y1856_MYCTU Putative oxidoreductase Rv1856c/M... | 247 | 0.00009 | 46.2 | 23 | 38 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 447 | P97852 | 735 | DHB4_RAT Peroxisomal multifunctional enzyme t... | 287 | 0.0001 | 47.4 | 21 | 39 | GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; TAS:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; NAS:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.] | 448 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 88 | 0.0001 | 46.6 | 32 | 49 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 449 | P54554 | 259 | YQJQ_BACSU Uncharacterized oxidoreductase yqj... | 244 | 0.0001 | 46.2 | 27 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 450 | P51659 | 736 | DHB4_HUMAN Peroxisomal multifunctional enzyme... | 302 | 0.0001 | 47 | 21 | 37 | GO:0005782; C:peroxisomal matrix; TAS:Reactome. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.::GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016508; F:long-chain-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.::GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome. | 451 | Q84ST4 | 343 | NOL_ORYSJ Chlorophyll(ide) b reductase NOL, c... | 86 | 0.0001 | 46.2 | 34 | 51 | GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0034256; F:chlorophyll(ide) b reductase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0015996; P:chlorophyll catabolic process; IEA:UniProtKB-KW. |
