| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q1ZXH9 | 466 | CP51_DICDI Probable lanosterol 14-alpha demet... | 326 | 0.0000000004 | 65.5 | 22 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 32 | Q27606 | 526 | CP4E2_DROME Cytochrome P450 4e2 OS=Drosophila... | 173 | 0.0000000005 | 65.5 | 27 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 33 | P15128 | 506 | CP4B1_RABIT Cytochrome P450 4B1 OS=Oryctolagu... | 190 | 0.0000000006 | 65.1 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 34 | Q09660 | 489 | CC44_CAEEL Probable cytochrome P450 CYP44 OS=... | 231 | 0.000000001 | 64.3 | 26 | 47 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 35 | B8NHY4 | 528 | ORDA_ASPFN O-methylsterigmatocystin oxidoredu... | 180 | 0.000000001 | 64.3 | 27 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 36 | Q5VDD6 | 528 | ORDA_ASPFL O-methylsterigmatocystin oxidoredu... | 180 | 0.000000001 | 64.3 | 27 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 37 | Q64464 | 503 | CP3AD_MOUSE Cytochrome P450 3A13 OS=Mus muscu... | 230 | 0.000000002 | 63.5 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010628; P:positive regulation of gene expression; IMP:MGI. | 38 | P33272 | 492 | CP2BC_RAT Cytochrome P450 2B12 OS=Rattus norv... | 265 | 0.000000002 | 63.5 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 39 | P13584 | 511 | CP4B1_HUMAN Cytochrome P450 4B1 OS=Homo sapie... | 303 | 0.000000002 | 63.5 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 40 | Q09653 | 519 | C13AA_CAEEL Putative cytochrome P450 CYP13A10... | 243 | 0.000000003 | 63.2 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; NAS:UniProtKB. | 41 | P78329 | 520 | CP4F2_HUMAN Leukotriene-B(4) omega-hydroxylas... | 192 | 0.000000003 | 62.8 | 27 | 43 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IDA:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0052872; F:tocotrienol omega-hydroxylase activity; IDA:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IMP:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; IMP:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; IMP:UniProtKB.::GO:0032304; P:negative regulation of icosanoid secretion; IMP:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0042360; P:vitamin E metabolic process; IDA:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; IMP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 42 | O23976 | 490 | C76B1_HELTU 7-ethoxycoumarin O-deethylase OS=... | 276 | 0.000000004 | 62.8 | 25 | 48 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 43 | Q9HCS2 | 524 | CP4FC_HUMAN Cytochrome P450 4F12 OS=Homo sapi... | 172 | 0.000000004 | 62.4 | 28 | 47 | GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; ISS:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; ISS:UniProtKB.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; ISS:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; ISS:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; ISS:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; ISS:UniProtKB.::GO:0003095; P:pressure natriuresis; ISS:UniProtKB.::GO:0003091; P:renal water homeostasis; ISS:UniProtKB.::GO:0055078; P:sodium ion homeostasis; ISS:UniProtKB.::GO:0042360; P:vitamin E metabolic process; ISS:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; ISS:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 44 | Q9VFJ0 | 492 | CP131_DROME Probable cytochrome P450 313a1 OS... | 175 | 0.000000004 | 62.4 | 31 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 45 | P56591 | 519 | CP1A1_SHEEP Cytochrome P450 1A1 OS=Ovis aries... | 168 | 0.000000004 | 62.4 | 27 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 46 | P04167 | 491 | CP2B2_RAT Cytochrome P450 2B2 OS=Rattus norve... | 287 | 0.000000005 | 62.4 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0018933; P:nicotine metabolic process; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 47 | P00176 | 491 | CP2B1_RAT Cytochrome P450 2B1 OS=Rattus norve... | 263 | 0.000000005 | 62 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010477; P:response to sulfur dioxide; IEP:RGD. | 48 | P98187 | 520 | CP4F8_HUMAN Cytochrome P450 4F8 OS=Homo sapie... | 187 | 0.000000006 | 62 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; TAS:ProtInc.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006693; P:prostaglandin metabolic process; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 49 | Q12645 | 515 | PID9_FUSSO Pisatin demethylase OS=Fusarium so... | 177 | 0.000000007 | 62 | 25 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 50 | P20815 | 502 | CP3A5_HUMAN Cytochrome P450 3A5 OS=Homo sapie... | 266 | 0.000000007 | 62 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 51 | Q9EP75 | 524 | CP4FE_MOUSE Leukotriene-B4 omega-hydroxylase ... | 192 | 0.000000007 | 61.6 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | | 52 | O44221 | 522 | CP4E5_DROMT Cytochrome P450 4e5, mitochondria... | 172 | 0.000000007 | 61.6 | 26 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 53 | O13345 | 528 | ORDA_ASPPA O-methylsterigmatocystin oxidoredu... | 180 | 0.000000008 | 61.6 | 26 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 54 | Q92113 | 509 | CP17A_SQUAC Steroid 17-alpha-hydroxylase/17,2... | 266 | 0.000000008 | 61.6 | 24 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 55 | P51871 | 537 | CP4F6_RAT Cytochrome P450 4F6 OS=Rattus norve... | 187 | 0.000000008 | 61.6 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; TAS:RGD.::GO:0006691; P:leukotriene metabolic process; IMP:RGD. | 56 | Q9JMA7 | 504 | CP341_MOUSE Cytochrome P450 3A41 OS=Mus muscu... | 232 | 0.000000008 | 61.6 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 57 | Q08477 | 520 | CP4F3_HUMAN Leukotriene-B(4) omega-hydroxylas... | 305 | 0.000000009 | 61.6 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 58 | Q92104 | 517 | CP11B_LITCT Cytochrome P450 11B, mitochondria... | 173 | 0.00000001 | 61.2 | 29 | 46 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 59 | Q3MID2 | 524 | CP4F3_RAT Leukotriene-B(4) omega-hydroxylase ... | 192 | 0.00000001 | 61.2 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | | 60 | P38364 | 506 | PID6_FUSSO Pisatin demethylase OS=Fusarium so... | 177 | 0.00000001 | 61.2 | 25 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 61 | O48958 | 531 | C71E1_SORBI 4-hydroxyphenylacetaldehyde oxime... | 312 | 0.00000001 | 61.2 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050592; F:4-hydroxyphenylacetaldehyde oxime monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0047085; F:hydroxyphenylacetonitrile 2-monooxygenase activity; IEA:EC. | | | | | | | | | | |
