| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | P10635 | 497 | CP2D6_HUMAN Cytochrome P450 2D6 OS=Homo sapie... | 284 | 0.00004 | 49.7 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0009804; P:coumarin metabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0033076; P:isoquinoline alkaloid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0051100; P:negative regulation of binding; IDA:BHF-UCL.::GO:0090350; P:negative regulation of cellular organofluorine metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL. | 302 | Q8L7D5 | 477 | THAH_ARATH Cytochrome P450 708A2 OS=Arabidops... | 226 | 0.00004 | 49.7 | 23 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0080014; F:thalianol hydroxylase activity; IMP:TAIR. | | | | | | | | | | GO:0048364; P:root development; IMP:TAIR.::GO:0080003; P:thalianol metabolic process; IMP:TAIR. | 303 | Q9PVE8 | 496 | C330_FUNHE Cytochrome P450 3A30 OS=Fundulus h... | 197 | 0.00004 | 49.7 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 304 | O46515 | 520 | CP11A_HORSE Cholesterol side-chain cleavage e... | 175 | 0.00005 | 49.7 | 25 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 305 | B9X287 | 542 | C7346_ORYSJ Cytochrome P450 734A6 OS=Oryza sa... | 220 | 0.00005 | 49.7 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:UniProtKB.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0010268; P:brassinosteroid homeostasis; IDA:UniProtKB.::GO:0016131; P:brassinosteroid metabolic process; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 306 | O22203 | 508 | C98A3_ARATH Cytochrome P450 98A3 OS=Arabidops... | 172 | 0.00005 | 49.7 | 21 | 48 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0046409; F:p-coumarate 3-hydroxylase activity; IDA:TAIR. | | | | | | | | | | GO:0009805; P:coumarin biosynthetic process; IMP:TAIR.::GO:0009813; P:flavonoid biosynthetic process; IMP:TAIR.::GO:0009809; P:lignin biosynthetic process; IMP:TAIR. | 307 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 188 | 0.00005 | 49.7 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 308 | Q9V558 | 513 | CP4P1_DROME Cytochrome P450 4p1 OS=Drosophila... | 193 | 0.00005 | 49.7 | 22 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 309 | Q29605 | 503 | CP19A_RABIT Cytochrome P450 19A1 OS=Oryctolag... | 312 | 0.00005 | 49.7 | 23 | 38 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro. | | | | | | | | | | | 310 | P56590 | 524 | CP1A1_CANFA Cytochrome P450 1A1 OS=Canis fami... | 168 | 0.00005 | 49.3 | 26 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 311 | P97720 | 499 | C11B1_MESAU Cytochrome P450 11B1, mitochondri... | 176 | 0.00006 | 49.3 | 24 | 47 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 312 | Q64409 | 503 | CP3AH_CAVPO Cytochrome P450 3A17 OS=Cavia por... | 177 | 0.00006 | 49.3 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 313 | Q91WL5 | 508 | CP4CA_MOUSE Cytochrome P450 4A12A OS=Mus musc... | 188 | 0.00006 | 49.3 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:MGI.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB. | 314 | Q8AXY5 | 496 | C356_FUNHE Cytochrome P450 3A56 OS=Fundulus h... | 197 | 0.00006 | 49.3 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 315 | Q69FB6 | 503 | CP19A_LAGAC Cytochrome P450 19A1 OS=Lagenorhy... | 308 | 0.00006 | 49.3 | 23 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 316 | P46194 | 503 | CP19A_BOVIN Cytochrome P450 19A1 OS=Bos tauru... | 311 | 0.00006 | 49.3 | 23 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 317 | P22680 | 504 | CP7A1_HUMAN Cholesterol 7-alpha-monooxygenase... | 183 | 0.00006 | 49.3 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 318 | Q29488 | 497 | CP2DH_MACFA Cytochrome P450 2D17 OS=Macaca fa... | 258 | 0.00006 | 49.3 | 23 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 319 | P93149 | 523 | C93B1_GLYEC Licodione synthase OS=Glycyrrhiza... | 212 | 0.00007 | 49.3 | 22 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033771; F:licodione synthase activity; IEA:EC. | | | | | | | | | | | 320 | Q9JKJ9 | 470 | CP39A_MOUSE 24-hydroxycholesterol 7-alpha-hyd... | 237 | 0.00007 | 48.9 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0033782; F:24-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB.::GO:0008387; F:steroid 7-alpha-hydroxylase activity; IDA:MGI. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0006707; P:cholesterol catabolic process; IDA:MGI.::GO:0007586; P:digestion; TAS:UniProtKB. | 321 | P79690 | 510 | CP191_CARAU Cytochrome P450 19 type 1 OS=Cara... | 256 | 0.00007 | 48.9 | 27 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 322 | P37114 | 506 | TCMO_MEDSA Trans-cinnamate 4-monooxygenase OS... | 162 | 0.00007 | 48.9 | 25 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:EC. | | | | | | | | | | | 323 | Q6V0L0 | 522 | CP26C_HUMAN Cytochrome P450 26C1 OS=Homo sapi... | 306 | 0.00007 | 48.9 | 23 | 40 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.::GO:0001972; F:retinoic acid binding; IDA:BHF-UCL. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.::GO:0007417; P:central nervous system development; ISS:BHF-UCL.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; NAS:BHF-UCL.::GO:0014032; P:neural crest cell development; ISS:BHF-UCL.::GO:0048284; P:organelle fusion; ISS:BHF-UCL.::GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 324 | Q05555 | 494 | CP2AA_RABIT Cytochrome P450 2A10 OS=Oryctolag... | 340 | 0.00008 | 48.9 | 22 | 36 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 325 | Q95M61 | 503 | CP19A_CALJA Cytochrome P450 19A1 OS=Callithri... | 340 | 0.00008 | 48.9 | 23 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 326 | P05177 | 515 | CP1A2_HUMAN Cytochrome P450 1A2 OS=Homo sapie... | 211 | 0.00008 | 48.9 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0032451; F:demethylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0009820; P:alkaloid metabolic process; IDA:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0032259; P:methylation; TAS:Reactome.::GO:0032787; P:monocarboxylic acid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0071615; P:oxidative deethylation; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0009403; P:toxin biosynthetic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 327 | O46512 | 503 | CP19A_HORSE Cytochrome P450 19A1 OS=Equus cab... | 170 | 0.00008 | 48.9 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 328 | O48922 | 509 | C98A2_SOYBN Cytochrome P450 98A2 OS=Glycine m... | 172 | 0.00009 | 48.9 | 22 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 329 | Q9VVR9 | 524 | C12C1_DROME Probable cytochrome P450 12c1, mi... | 202 | 0.0001 | 48.5 | 26 | 47 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 330 | P33616 | 512 | CP1A1_MACFA Cytochrome P450 1A1 OS=Macaca fas... | 170 | 0.0001 | 48.5 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 331 | Q6Z6D6 | 557 | C7342_ORYSJ Cytochrome P450 734A2 OS=Oryza sa... | 218 | 0.0001 | 48.5 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0010268; P:brassinosteroid homeostasis; IDA:UniProtKB.::GO:0016131; P:brassinosteroid metabolic process; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. |
