rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08023 | 583 | FMP25_YEAST Protein FMP25, mitochondrial OS=S... | 485 | 0.000000000000002 | 83.2 | 23 | 38 | GO:0031305; C:integral to mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0034551; P:mitochondrial respiratory chain complex III assembly; IMP:SGD. | 2 | Q5GLZ8 | 1057 | HERC4_HUMAN Probable E3 ubiquitin-protein lig... | 211 | 7.7 | 33.5 | 21 | 38 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 3 | Q5PQN1 | 1057 | HERC4_RAT Probable E3 ubiquitin-protein ligas... | 408 | 0.0000003 | 57.4 | 23 | 33 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 4 | Q6PAV2 | 1057 | HERC4_MOUSE Probable E3 ubiquitin-protein lig... | 211 | 6.6 | 33.5 | 21 | 38 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 5 | Q5RCZ7 | 551 | RCBT2_PONAB RCC1 and BTB domain-containing pr... | 168 | 0.0005 | 46.6 | 26 | 42 | | | | | | | | | | | | | | | | | | | | | | 6 | O95199 | 551 | RCBT2_HUMAN RCC1 and BTB domain-containing pr... | 168 | 0.0005 | 46.6 | 26 | 42 | | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | | 7 | Q6P798 | 551 | RCBT2_RAT RCC1 and BTB domain-containing prot... | 185 | 0.0002 | 47.8 | 25 | 43 | | | | | | | | | | | | | | | | | | | | | | 8 | Q99LJ7 | 551 | RCBT2_MOUSE RCC1 and BTB domain-containing pr... | 185 | 0.0004 | 47 | 25 | 42 | | | | | | | | | | | | | | | | | | | | | | 9 | Q15034 | 1050 | HERC3_HUMAN Probable E3 ubiquitin-protein lig... | 281 | 8.4 | 33.1 | 20 | 38 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 10 | Q15751 | 4861 | HERC1_HUMAN Probable E3 ubiquitin-protein lig... | 42 | 8.5 | 33.5 | 36 | 57 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 11 | Q9VR91 | 4912 | HERC2_DROME Probable E3 ubiquitin-protein lig... | 135 | 2.6 | 35 | 23 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 12 | Q9N1T2 | 1003 | RPGR_CANFA X-linked retinitis pigmentosa GTPa... | 161 | 0.0006 | 46.6 | 26 | 45 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB. | 13 | Q6NXM2 | 531 | RCBT1_MOUSE RCC1 and BTB domain-containing pr... | 152 | 6.7 | 33.5 | 27 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q92834 | 1020 | RPGR_HUMAN X-linked retinitis pigmentosa GTPa... | 163 | 0.001 | 45.8 | 26 | 45 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.::GO:0001750; C:photoreceptor outer segment; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; TAS:ProtInc.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IMP:UniProtKB. | 15 | O95714 | 4834 | HERC2_HUMAN E3 ubiquitin-protein ligase HERC2... | 292 | 5.3 | 33.9 | 21 | 38 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 16 | Q4U2R1 | 4836 | HERC2_MOUSE E3 ubiquitin-protein ligase HERC2... | 167 | 1.5 | 35.8 | 23 | 40 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI. | 17 | Q9UII4 | 1024 | HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS... | 169 | 3.4 | 34.7 | 26 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 18 | Q8IVU3 | 1022 | HERC6_HUMAN Probable E3 ubiquitin-protein lig... | 275 | 0.004 | 43.9 | 26 | 42 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 19 | Q9R0X5 | 1001 | RPGR_MOUSE X-linked retinitis pigmentosa GTPa... | 168 | 0.007 | 43.1 | 26 | 45 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005929; C:cilium; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0042462; P:eye photoreceptor cell development; IMP:MGI.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB. | 20 | Q52KW8 | 513 | RCC2_XENLA Protein RCC2 homolog OS=Xenopus la... | 62 | 3.4 | 34.3 | 37 | 53 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 21 | Q54Q89 | 487 | RCCDC_DICDI RCC1 repeat-containing protein DD... | 203 | 0.008 | 42.7 | 23 | 40 | | | | | | | | | | | | | | | | | | | | | | 22 | Q8NDN9 | 531 | RCBT1_HUMAN RCC1 and BTB domain-containing pr... | 167 | 0.068 | 39.7 | 24 | 40 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q5DX34 | 1392 | RPGRH_CAEEL X-linked retinitis pigmentosa GTP... | 178 | 1.1 | 36.2 | 21 | 38 | GO:0030424; C:axon; IDA:WormBase.::GO:0045202; C:synapse; IDA:WormBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019915; P:lipid storage; IMP:WormBase. | 24 | Q9P258 | 522 | RCC2_HUMAN Protein RCC2 OS=Homo sapiens (Huma... | 171 | 0.026 | 41.2 | 26 | 38 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000236; P:mitotic prometaphase; TAS:Reactome. | 25 | P21827 | 482 | RCC1_YEAST Guanine nucleotide exchange factor... | 80 | 0.45 | 37 | 29 | 48 | GO:0000790; C:nuclear chromatin; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006407; P:rRNA export from nucleus; IMP:SGD. | 26 | P28745 | 539 | RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce... | 323 | 0.032 | 40.8 | 24 | 38 | GO:0000790; C:nuclear chromatin; NAS:PomBase. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase. | 27 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 188 | 3.4 | 34.3 | 21 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q8BK67 | 520 | RCC2_MOUSE Protein RCC2 OS=Mus musculus (Mous... | 132 | 8.3 | 33.1 | 27 | 45 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 29 | Q6NYE2 | 495 | RCC2_DANRE Protein RCC2 homolog OS=Danio reri... | 90 | 0.24 | 38.1 | 34 | 47 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 30 | Q4R828 | 376 | RCCD1_MACFA RCC1 domain-containing protein 1 ... | 182 | 1.4 | 35.4 | 23 | 36 | | | | | | | | | | | | | | | | | | | | | | 31 | Q9UGK8 | 458 | SRGEF_HUMAN Secretion-regulating guanine nucl... | 139 | 0.43 | 37 | 28 | 41 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; IDA:HGNC.::GO:0007165; P:signal transduction; TAS:UniProtKB. |