| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
961 | B7ZR30 | 950 | STK10_XENLA Serine/threonine-protein kinase 1... | 206 | 2e-16 | 84.7 | 32 | 51 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 962 | Q6Z9F4 | 451 | CIPK6_ORYSJ CBL-interacting protein kinase 6 ... | 213 | 2e-16 | 84 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 963 | Q54TN4 | 715 | MKCE_DICDI Probable serine/threonine-protein ... | 197 | 2e-16 | 84.7 | 30 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 964 | B4NSS9 | 743 | DCLK_DROSI Serine/threonine-protein kinase GD... | 216 | 2e-16 | 84.7 | 31 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 965 | Q8R4V0 | 496 | SGK3_RAT Serine/threonine-protein kinase Sgk3... | 342 | 2e-16 | 84.3 | 27 | 40 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 966 | Q03497 | 939 | STE20_YEAST Serine/threonine-protein kinase S... | 242 | 2e-16 | 84.7 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:SGD. | | | | | | | | | | GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD. | 967 | P36887 | 351 | KAPCA_PIG cAMP-dependent protein kinase catal... | 225 | 2e-16 | 83.2 | 30 | 51 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 968 | Q16566 | 473 | KCC4_HUMAN Calcium/calmodulin-dependent prote... | 292 | 2e-16 | 84 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; IGI:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; TAS:UniProtKB.::GO:0033081; P:regulation of T cell differentiation in thymus; TAS:UniProtKB. | 969 | Q6FN53 | 915 | STE20_CANGA Serine/threonine-protein kinase S... | 223 | 3e-16 | 84.7 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 970 | P27466 | 446 | KCC1_YEAST Calcium/calmodulin-dependent prote... | 244 | 3e-16 | 84 | 31 | 46 | GO:0005737; C:cytoplasm; IPI:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD. | | | | | | | | | | GO:0007165; P:signal transduction; IMP:SGD. | 971 | Q7RAH3 | 535 | CDPK1_PLAYO Calcium-dependent protein kinase ... | 252 | 3e-16 | 84 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 972 | Q8RXT4 | 555 | NEK4_ARATH Serine/threonine-protein kinase Ne... | 228 | 3e-16 | 84 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 973 | Q8SWM6 | 488 | CDC5_ENCCU Probable cell cycle serine/threoni... | 296 | 3e-16 | 84 | 28 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 974 | Q9NYY3 | 685 | PLK2_HUMAN Serine/threonine-protein kinase PL... | 213 | 3e-16 | 84.3 | 29 | 48 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; IDA:UniProtKB. | 975 | P0C8E4 | 606 | M3K7_RAT Mitogen-activated protein kinase kin... | 202 | 3e-16 | 84 | 32 | 50 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 976 | P46734 | 347 | MP2K3_HUMAN Dual specificity mitogen-activate... | 287 | 3e-16 | 82.8 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 977 | A2VDU3 | 579 | M3K7_BOVIN Mitogen-activated protein kinase k... | 202 | 3e-16 | 84 | 32 | 50 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 978 | O43318 | 606 | M3K7_HUMAN Mitogen-activated protein kinase k... | 202 | 3e-16 | 84 | 32 | 50 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0007252; P:I-kappaB phosphorylation; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 979 | Q5RFL3 | 606 | M3K7_PONAB Mitogen-activated protein kinase k... | 202 | 3e-16 | 84 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 980 | Q63531 | 735 | KS6A1_RAT Ribosomal protein S6 kinase alpha-1... | 333 | 0.000000000000002 | 81.6 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004711; F:ribosomal protein S6 kinase activity; TAS:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:RGD. | 981 | P10665 | 733 | KS6AA_XENLA Ribosomal protein S6 kinase 2 alp... | 291 | 0.000000000000002 | 82 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 982 | Q9WUT3 | 733 | KS6A2_MOUSE Ribosomal protein S6 kinase alpha... | 285 | 0.000000000000002 | 81.6 | 26 | 45 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004711; F:ribosomal protein S6 kinase activity; IDA:MGI. | | | | | | | | | | GO:0002035; P:brain renin-angiotensin system; IDA:MGI.::GO:0010659; P:cardiac muscle cell apoptotic process; IDA:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0060047; P:heart contraction; IDA:MGI.::GO:0007507; P:heart development; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0000089; P:mitotic metaphase; IDA:MGI.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0070613; P:regulation of protein processing; IDA:MGI. | 983 | P18653 | 724 | KS6A1_MOUSE Ribosomal protein S6 kinase alpha... | 295 | 0.000000000000003 | 81.3 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB. | 984 | Q15349 | 733 | KS6A2_HUMAN Ribosomal protein S6 kinase alpha... | 286 | 0.000000000000008 | 79.7 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 985 | P18652 | 752 | KS6AA_CHICK Ribosomal protein S6 kinase 2 alp... | 332 | 0.00000000000001 | 79.3 | 25 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 986 | Q15418 | 735 | KS6A1_HUMAN Ribosomal protein S6 kinase alpha... | 292 | 0.00000000000003 | 78.2 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 987 | Q7TPS0 | 764 | KS6A6_MOUSE Ribosomal protein S6 kinase alpha... | 338 | 0.00000000000003 | 77.8 | 24 | 43 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; IDA:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; IDA:UniProtKB. | 988 | P10666 | 629 | KS6AB_XENLA Ribosomal protein S6 kinase 2 bet... | 228 | 0.00000000000009 | 76.6 | 27 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 989 | P18654 | 740 | KS6A3_MOUSE Ribosomal protein S6 kinase alpha... | 305 | 0.0000000000002 | 75.5 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0032496; P:response to lipopolysaccharide; IMP:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB. | 990 | P51812 | 740 | KS6A3_HUMAN Ribosomal protein S6 kinase alpha... | 305 | 0.0000000000002 | 75.5 | 25 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 991 | Q6PFQ0 | 740 | KS6A6_DANRE Ribosomal protein S6 kinase alpha... | 350 | 0.0000000000002 | 75.9 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. |
