| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q99L13 | 335 | 3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenas... | 325 | 6e-74 | 238 | 40 | 58 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 2 | P29266 | 335 | 3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase,... | 325 | 8e-74 | 238 | 40 | 58 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 3 | P31937 | 336 | 3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenas... | 325 | 5e-73 | 235 | 40 | 58 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; NAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; NAS:UniProtKB. | 4 | Q2HJD7 | 336 | 3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenas... | 325 | 9e-73 | 234 | 40 | 58 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 5 | Q5R5E7 | 336 | 3HIDH_PONAB 3-hydroxyisobutyrate dehydrogenas... | 325 | 3e-72 | 233 | 39 | 58 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 6 | Q9XTI0 | 299 | 3HIDH_CAEEL Probable 3-hydroxyisobutyrate deh... | 316 | 1e-68 | 223 | 43 | 57 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 7 | Q9V8M5 | 324 | 3HIDH_DROME Probable 3-hydroxyisobutyrate deh... | 326 | 2e-64 | 213 | 39 | 54 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 8 | Q54CX6 | 321 | 3HIDH_DICDI Probable 3-hydroxyisobutyrate deh... | 317 | 7e-63 | 209 | 42 | 58 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 9 | Q9SUC0 | 347 | 3HIDH_ARATH Probable 3-hydroxyisobutyrate deh... | 324 | 3e-60 | 202 | 40 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 10 | P28811 | 298 | MMSB_PSEAE 3-hydroxyisobutyrate dehydrogenase... | 314 | 2e-54 | 186 | 37 | 54 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 11 | P63935 | 294 | MMSB_MYCTU Probable 3-hydroxyisobutyrate dehy... | 319 | 8e-52 | 179 | 39 | 54 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 12 | P63936 | 294 | MMSB_MYCBO Probable 3-hydroxyisobutyrate dehy... | 319 | 8e-52 | 179 | 39 | 54 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 13 | Q0QLF5 | 301 | HMGD_EUBBA 2-(hydroxymethyl)glutarate dehydro... | 325 | 2e-29 | 119 | 30 | 46 | | | | | | | | | | | GO:0043718; F:2-hydroxymethylglutarate dehydrogenase activity; IDA:UniProtKB.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 14 | O34948 | 288 | YKWC_BACSU Uncharacterized oxidoreductase ykw... | 294 | 1e-27 | 114 | 31 | 47 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 15 | Q55702 | 290 | Y229_SYNY3 Uncharacterized oxidoreductase slr... | 289 | 8e-27 | 111 | 31 | 49 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 16 | P0ABQ2 | 294 | GARR_ECOLI 2-hydroxy-3-oxopropionate reductas... | 283 | 2e-26 | 110 | 32 | 48 | | | | | | | | | | | GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0019582; P:D-galactarate catabolic process; IDA:EcoCyc.::GO:0042838; P:D-glucarate catabolic process; IDA:EcoCyc.::GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 17 | P0ABQ3 | 294 | GARR_ECOL6 2-hydroxy-3-oxopropionate reductas... | 283 | 2e-26 | 110 | 32 | 48 | | | | | | | | | | | GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IEA:EC.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 18 | P0A9V9 | 298 | YIHU_SHIFL Uncharacterized oxidoreductase yih... | 322 | 1e-24 | 105 | 30 | 47 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 19 | P0A9V8 | 298 | YIHU_ECOLI Uncharacterized oxidoreductase yih... | 322 | 1e-24 | 105 | 30 | 47 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0047577; F:4-hydroxybutyrate dehydrogenase activity; IDA:EcoCyc.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0009407; P:toxin catabolic process; IMP:EcoCyc.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 20 | Q9L7S0 | 298 | YIHU_SALTY Uncharacterized oxidoreductase yih... | 318 | 4e-24 | 103 | 27 | 47 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 21 | P77161 | 292 | GLXR_ECOLI 2-hydroxy-3-oxopropionate reductas... | 279 | 2e-21 | 95.9 | 32 | 46 | | | | | | | | | | | GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0009442; P:allantoin assimilation pathway; IEP:EcoCyc.::GO:0009436; P:glyoxylate catabolic process; IMP:EcoCyc.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 22 | O33730 | 291 | Y1503_SHEFN Uncharacterized oxidoreductase Sf... | 295 | 3e-18 | 86.7 | 26 | 43 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 23 | P44979 | 301 | Y1010_HAEIN Uncharacterized oxidoreductase HI... | 212 | 0.0000000000002 | 73.2 | 29 | 49 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. | 24 | Q5R7T2 | 553 | GLYR1_PONAB Putative oxidoreductase GLYR1 OS=... | 320 | 0.00000001 | 59.7 | 24 | 35 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 25 | Q5ZLS7 | 553 | GLYR1_CHICK Putative oxidoreductase GLYR1 OS=... | 204 | 0.00000002 | 58.9 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 26 | Q562D5 | 534 | GLYR1_XENTR Putative oxidoreductase GLYR1 OS=... | 321 | 0.00000002 | 58.9 | 24 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 27 | Q5RKH0 | 552 | GLYR1_RAT Putative oxidoreductase GLYR1 OS=Ra... | 204 | 0.00000003 | 58.5 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 28 | Q922P9 | 546 | GLYR1_MOUSE Putative oxidoreductase GLYR1 OS=... | 204 | 0.00000004 | 58.5 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 29 | A4FUF0 | 553 | GLYR1_BOVIN Putative oxidoreductase GLYR1 OS=... | 204 | 0.00000004 | 58.2 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 30 | Q49A26 | 553 | GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=... | 204 | 0.0000001 | 56.6 | 25 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. | 31 | Q46888 | 302 | YGBJ_ECOLI Uncharacterized oxidoreductase ygb... | 245 | 0.0000002 | 55.5 | 25 | 44 | | | | | | | | | | | GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro. | | | | | | | | | | GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro. |
