rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q869T1 | 335 | TWF_DICDI Twinfilin OS=Dictyostelium discoide... | 329 | 6e-51 | 178 | 31 | 52 | GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; ISS:dictyBase. | | | | | | | | | | | 2 | Q7ZXP0 | 349 | TWF2A_XENLA Twinfilin-2-A OS=Xenopus laevis (... | 358 | 7e-45 | 162 | 31 | 51 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 3 | Q6IBS0 | 349 | TWF2_HUMAN Twinfilin-2 OS=Homo sapiens (Human... | 359 | 6e-44 | 160 | 33 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030426; C:growth cone; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.::GO:0032420; C:stereocilium; ISS:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.::GO:0005080; F:protein kinase C binding; IPI:BHF-UCL. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; ISS:BHF-UCL.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; IMP:BHF-UCL.::GO:0010592; P:positive regulation of lamellipodium assembly; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0032532; P:regulation of microvillus length; IC:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL. | 4 | Q640W2 | 349 | TWF2B_XENLA Twinfilin-2-B OS=Xenopus laevis (... | 358 | 3e-43 | 158 | 31 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q9Z0P5 | 349 | TWF2_MOUSE Twinfilin-2 OS=Mus musculus (Mouse... | 359 | 9e-43 | 157 | 32 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; IDA:BHF-UCL.::GO:0030016; C:myofibril; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0032420; C:stereocilium; IDA:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0030837; P:negative regulation of actin filament polymerization; IDA:BHF-UCL.::GO:0032532; P:regulation of microvillus length; IC:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; IDA:BHF-UCL. | 6 | Q17A58 | 343 | TWF_AEDAE Twinfilin OS=Aedes aegypti (Yellowf... | 362 | 2e-42 | 155 | 31 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q298X4 | 345 | TWF_DROPS Twinfilin OS=Drosophila pseudoobscu... | 360 | 8e-42 | 154 | 30 | 48 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB. | | | | | | | | | | GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 8 | Q5ZM35 | 349 | TWF2_CHICK Twinfilin-2 OS=Gallus gallus (Chic... | 358 | 1e-40 | 151 | 31 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q5R7N2 | 350 | TWF1_PONAB Twinfilin-1 OS=Pongo abelii (Sumat... | 358 | 4e-40 | 150 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q5RFH1 | 341 | TWF2_PONAB Twinfilin-2 OS=Pongo abelii (Sumat... | 347 | 7e-40 | 149 | 33 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW. | 11 | Q12792 | 350 | TWF1_HUMAN Twinfilin-1 OS=Homo sapiens (Human... | 358 | 7e-40 | 149 | 30 | 47 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:BHF-UCL.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL. | | | | | | | | | | GO:0043538; P:regulation of actin phosphorylation; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL. | 12 | Q56JV6 | 350 | TWF1_BOVIN Twinfilin-1 OS=Bos taurus (Bovine)... | 358 | 9e-40 | 149 | 30 | 47 | | | | | | | | | | | | | | | | | | | | | | 13 | Q7QG28 | 343 | TWF_ANOGA Twinfilin OS=Anopheles gambiae (Afr... | 360 | 1e-39 | 148 | 31 | 47 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q5RJR2 | 350 | TWF1_RAT Twinfilin-1 OS=Rattus norvegicus (Ra... | 358 | 5e-39 | 147 | 30 | 48 | | | | | | | | | | | | | | | | | | | | | | 15 | Q91YR1 | 350 | TWF1_MOUSE Twinfilin-1 OS=Mus musculus (Mouse... | 358 | 6e-39 | 146 | 29 | 48 | GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:BHF-UCL.::GO:0030016; C:myofibril; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.::GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; IDA:BHF-UCL. | 16 | Q9VFM9 | 343 | TWF_DROME Twinfilin OS=Drosophila melanogaste... | 360 | 3e-37 | 142 | 29 | 46 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IMP:UniProtKB. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0008407; P:chaeta morphogenesis; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0030833; P:regulation of actin filament polymerization; IMP:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 17 | Q5I082 | 350 | TWF1_XENTR Twinfilin-1 OS=Xenopus tropicalis ... | 363 | 4e-36 | 139 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q68F50 | 350 | TWF1_XENLA Twinfilin-1 OS=Xenopus laevis (Afr... | 363 | 2e-35 | 137 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | Q6GMH3 | 347 | TWF2_DANRE Twinfilin-2 OS=Danio rerio (Zebraf... | 332 | 1e-30 | 123 | 29 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | P53250 | 332 | TWF1_YEAST Twinfilin-1 OS=Saccharomyces cerev... | 363 | 3e-19 | 90.5 | 26 | 45 | GO:0030479; C:actin cortical patch; TAS:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:SGD. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0042989; P:sequestering of actin monomers; IDA:SGD. | 21 | O94399 | 328 | TWF1_SCHPO Twinfilin OS=Schizosaccharomyces p... | 308 | 4e-19 | 90.1 | 25 | 49 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:PomBase. | | | | | | | | | | GO:0042989; P:sequestering of actin monomers; ISS:PomBase. | 22 | P78929 | 137 | COFI_SCHPO Cofilin OS=Schizosaccharomyces pom... | 97 | 0.00007 | 45.8 | 28 | 49 | GO:0030479; C:actin cortical patch; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071519; P:actin filament bundle assembly involved in actomyosin contractile ring formation; NAS:PomBase.::GO:0030042; P:actin filament depolymerization; TAS:PomBase. | 23 | Q9LQ81 | 140 | ADF10_ARATH Actin-depolymerizing factor 10 OS... | 114 | 0.01 | 39.3 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q570Y6 | 140 | ADF8_ARATH Actin-depolymerizing factor 8 OS=A... | 114 | 0.055 | 37.4 | 25 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 25 | Q43694 | 139 | ADF2_MAIZE Actin-depolymerizing factor 2 OS=Z... | 114 | 0.0009 | 42.4 | 27 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q5U4Y2 | 167 | COF2_XENTR Cofilin-2 OS=Xenopus tropicalis (W... | 88 | 0.001 | 42.7 | 20 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | Q5XHH8 | 167 | COF2_XENLA Cofilin-2 OS=Xenopus laevis (Afric... | 88 | 0.001 | 42.7 | 20 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q9ZSK4 | 139 | ADF3_ARATH Actin-depolymerizing factor 3 OS=A... | 85 | 0.12 | 36.2 | 27 | 51 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR. | 29 | P46251 | 139 | ADF1_MAIZE Actin-depolymerizing factor 1 OS=Z... | 114 | 0.002 | 41.6 | 27 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | Q8LFH6 | 137 | ADF12_ARATH Actin-depolymerizing factor 12 OS... | 114 | 0.003 | 41.2 | 27 | 48 | GO:0005884; C:actin filament; IDA:TAIR. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 31 | Q6CQ22 | 143 | COFI_KLULA Cofilin OS=1267 / NRRL Y-1140 / WM... | 113 | 0.14 | 36.2 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. |