rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q6CQ22 | 143 | COFI_KLULA Cofilin OS=1267 / NRRL Y-1140 / WM... | 113 | 0.14 | 36.2 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 32 | Q6C0Y0 | 153 | COFI_YARLI Cofilin OS=lipolytica). GN=COF1 Or... | 75 | 0.56 | 34.7 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 33 | Q9AY76 | 145 | ADF2_ORYSJ Actin-depolymerizing factor 2 OS=O... | 99 | 0.68 | 34.3 | 22 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 34 | P23528 | 166 | COF1_HUMAN Cofilin-1 OS=Homo sapiens (Human).... | 70 | 3.1 | 32.7 | 27 | 47 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 35 | Q9HF97 | 143 | COFI_ZYGRO Cofilin OS=Zygosaccharomyces rouxi... | 94 | 0.034 | 38.1 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 36 | P37167 | 138 | ACTP_ACACA Actophorin OS=Acanthamoeba castell... | 116 | 0.009 | 39.7 | 23 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 37 | P45592 | 166 | COF1_RAT Cofilin-1 OS=Rattus norvegicus (Rat)... | 88 | 0.009 | 40 | 22 | 45 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IMP:RGD. | | | | | | | | | | GO:0030030; P:cell projection organization; IDA:MGI.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IDA:MGI.::GO:0006606; P:protein import into nucleus; IMP:RGD.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 38 | Q39251 | 137 | ADF2_ARATH Actin-depolymerizing factor 2 OS=A... | 114 | 0.01 | 39.3 | 27 | 49 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 39 | Q67ZM4 | 137 | ADF7_ARATH Actin-depolymerizing factor 7 OS=A... | 114 | 0.64 | 34.3 | 25 | 46 | GO:0005884; C:actin filament; IDA:TAIR. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 40 | P86292 | 122 | CADF1_PLAFX Cofilin/actin-depolymerizing fact... | 115 | 0.017 | 38.5 | 27 | 43 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; IMP:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; IMP:UniProtKB. | 41 | Q8I467 | 122 | CADF1_PLAF7 Cofilin/actin-depolymerizing fact... | 115 | 0.017 | 38.5 | 27 | 43 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB. | 42 | P18760 | 166 | COF1_MOUSE Cofilin-1 OS=Mus musculus (Mouse).... | 88 | 0.02 | 38.9 | 20 | 45 | GO:0030864; C:cortical actin cytoskeleton; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0000910; P:cytokinesis; IMP:MGI.::GO:0030010; P:establishment of cell polarity; IMP:MGI.::GO:0001755; P:neural crest cell migration; IMP:MGI.::GO:0001842; P:neural fold formation; IMP:MGI.::GO:0030836; P:positive regulation of actin filament depolymerization; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:MGI. | 43 | Q6B7M7 | 166 | COF1_SHEEP Cofilin-1 OS=Ovis aries (Sheep). G... | 70 | 3.3 | 32.3 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 44 | P10668 | 166 | COF1_PIG Cofilin-1 OS=Sus scrofa (Pig). GN=CF... | 70 | 3.3 | 32.3 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 45 | Q4R5C0 | 166 | COF1_MACFA Cofilin-1 OS=Macaca fascicularis (... | 70 | 3.3 | 32.3 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 46 | Q5E9F7 | 166 | COF1_BOVIN Cofilin-1 OS=Bos taurus (Bovine). ... | 70 | 3.3 | 32.3 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031258; C:lamellipodium membrane; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 47 | Q8H2P8 | 139 | ADF9_ORYSJ Actin-depolymerizing factor 9 OS=O... | 114 | 0.024 | 38.5 | 27 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | Q9ZSK3 | 139 | ADF4_ARATH Actin-depolymerizing factor 4 OS=A... | 90 | 0.026 | 38.1 | 23 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009870; P:defense response signaling pathway, resistance gene-dependent; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR. | 49 | Q9FVI2 | 139 | ADF1_PETHY Actin-depolymerizing factor 1 OS=P... | 116 | 0.026 | 38.1 | 28 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | Q759P0 | 143 | COFI_ASHGO Cofilin OS=Y-1056) (Yeast) (Eremot... | 112 | 0.18 | 35.8 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 51 | Q2QLT8 | 145 | ADF11_ORYSJ Actin-depolymerizing factor 11 OS... | 114 | 0.036 | 37.7 | 25 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 52 | Q6FV81 | 143 | COFI_CANGA Cofilin OS=NRRL Y-65) (Yeast) (Tor... | 109 | 0.35 | 35 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 53 | Q6BWX4 | 143 | COFI_DEBHA Cofilin OS=0083 / IGC 2968) (Yeast... | 114 | 0.2 | 35.8 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 54 | Q03048 | 143 | COFI_YEAST Cofilin OS=Saccharomyces cerevisia... | 109 | 0.068 | 37 | 30 | 50 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:SGD.::GO:0051014; P:actin filament severing; IDA:SGD. | 55 | P30175 | 139 | ADF_LILLO Actin-depolymerizing factor OS=Lili... | 114 | 0.049 | 37.4 | 25 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | Q96VU9 | 143 | COFI_PICAD Cofilin OS=(Hansenula polymorpha).... | 109 | 1 | 33.5 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 57 | P45695 | 168 | COF1A_XENLA Cofilin-1-A OS=Xenopus laevis (Af... | 88 | 0.059 | 37.7 | 20 | 45 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:UniProtKB.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 58 | P21566 | 166 | COF2_CHICK Cofilin-2 OS=Gallus gallus (Chicke... | 88 | 0.067 | 37.4 | 19 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | P18359 | 165 | DEST_CHICK Destrin OS=Gallus gallus (Chicken)... | 105 | 0.074 | 37.4 | 19 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 60 | Q5G6V9 | 166 | COF2_PIG Cofilin-2 OS=Sus scrofa (Pig). GN=CF... | 49 | 0.074 | 37.4 | 29 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 61 | Q9Y281 | 166 | COF2_HUMAN Cofilin-2 OS=Homo sapiens (Human).... | 49 | 0.074 | 37.4 | 29 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | |