rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
601 | P48758 | 277 | CBR1_MOUSE Carbonyl reductase [NADPH] 1 OS=Mu... | 147 | 0.4 | 35.4 | 22 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 602 | O24990 | 275 | FABI_HELPY Enoyl-[acyl-carrier-protein] reduc... | 215 | 0.44 | 35 | 24 | 43 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 603 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 211 | 0.44 | 35.4 | 23 | 39 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 604 | Q02337 | 344 | BDH_BOVIN D-beta-hydroxybutyrate dehydrogenas... | 88 | 0.45 | 35.4 | 23 | 51 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 605 | Q03133 | 3172 | ERYA3_SACER Erythronolide synthase, modules 5... | 138 | 0.47 | 35.8 | 25 | 42 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0047879; F:erythronolide synthase activity; IEA:EC.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 606 | A6ZLA1 | 347 | MKAR_YEAS7 3-ketoacyl-CoA reductase OS=Saccha... | 206 | 0.5 | 35 | 23 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 607 | B3LN00 | 347 | MKAR_YEAS1 3-ketoacyl-CoA reductase OS=Saccha... | 206 | 0.5 | 35 | 23 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 608 | Q8CEE7 | 334 | RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus m... | 215 | 0.57 | 35 | 23 | 39 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 609 | Q00669 | 254 | ADH_DROAD Alcohol dehydrogenase OS=Drosophila... | 200 | 0.58 | 34.7 | 23 | 43 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 610 | Q2UET3 | 346 | MKAR_ASPOR 3-ketoacyl-CoA reductase OS=Asperg... | 209 | 0.59 | 35 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 611 | Q6CHP1 | 389 | MKAR_YARLI 3-ketoacyl-CoA reductase OS=lipoly... | 217 | 0.62 | 35 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 612 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 191 | 0.68 | 34.7 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 613 | O88876 | 302 | DHRS3_MOUSE Short-chain dehydrogenase/reducta... | 133 | 0.94 | 34.3 | 22 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 614 | P51658 | 381 | DHB2_MOUSE Estradiol 17-beta-dehydrogenase 2 ... | 211 | 0.96 | 34.3 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | | 615 | Q92781 | 318 | RDH1_HUMAN 11-cis retinol dehydrogenase OS=Ho... | 233 | 1.1 | 34.3 | 25 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; TAS:ProtInc. | 616 | Q10245 | 341 | MKAR_SCHPO 3-ketoacyl-CoA reductase OS=Schizo... | 188 | 1.1 | 34.3 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045703; F:ketoreductase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:PomBase. | 617 | O14756 | 317 | H17B6_HUMAN 17-beta-hydroxysteroid dehydrogen... | 83 | 1.2 | 33.9 | 25 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; NAS:UniProtKB.::GO:0006710; P:androgen catabolic process; TAS:UniProtKB. | 618 | Q803A8 | 412 | WWOX_DANRE WW domain-containing oxidoreductas... | 214 | 1.3 | 33.9 | 22 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 619 | P39853 | 599 | CAPD_STAAU Capsular polysaccharide biosynthes... | 112 | 1.5 | 33.9 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW. | 620 | Q02338 | 343 | BDH_HUMAN D-beta-hydroxybutyrate dehydrogenas... | 111 | 1.6 | 33.5 | 24 | 48 | GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.::GO:0046952; P:ketone body catabolic process; TAS:Reactome. | 621 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 214 | 1.8 | 33.5 | 21 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 622 | Q3SZD7 | 277 | CBR1_BOVIN Carbonyl reductase [NADPH] 1 OS=Bo... | 100 | 1.9 | 33.1 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 623 | Q6CLN0 | 313 | TSC10_KLULA 3-ketodihydrosphingosine reductas... | 100 | 1.9 | 33.1 | 24 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 624 | P38286 | 347 | MKAR_YEAST 3-ketoacyl-CoA reductase OS=Saccha... | 206 | 1.9 | 33.5 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045703; F:ketoreductase activity; IPI:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; IPI:SGD. | 625 | Q7Z5J1 | 315 | DHI1L_HUMAN Hydroxysteroid 11-beta-dehydrogen... | 189 | 2 | 33.1 | 26 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 626 | P28486 | 272 | ADHR_DROTE Alcohol dehydrogenase-related 31 k... | 200 | 2.1 | 33.1 | 26 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 627 | Q5SS80 | 376 | DHR13_MOUSE Dehydrogenase/reductase SDR famil... | 212 | 2.2 | 33.1 | 23 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 628 | Q6Q7D2 | 287 | DHI1L_MACFA Hydroxysteroid 11-beta-dehydrogen... | 185 | 2.2 | 33.1 | 25 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 629 | P66784 | 254 | Y3820_MYCBO Uncharacterized oxidoreductase Mb... | 128 | 2.3 | 32.7 | 21 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 630 | P66783 | 254 | DPRE2_MYCTU Probable decaprenylphosphoryl-D-2... | 128 | 2.3 | 32.7 | 21 | 44 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035884; P:arabinan biosynthetic process; IDA:MTBBASE.::GO:0070592; P:cell wall polysaccharide biosynthetic process; IDA:MTBBASE.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:MTBBASE. | 631 | Q9R092 | 317 | H17B6_MOUSE 17-beta-hydroxysteroid dehydrogen... | 219 | 2.3 | 33.1 | 25 | 42 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. |