rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P52895 | 323 | AK1C2_HUMAN Aldo-keto reductase family 1 memb... | 307 | 3e-34 | 132 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB. | 32 | Q5R5D5 | 325 | AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O... | 287 | 3e-34 | 131 | 33 | 51 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 33 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 319 | 4e-34 | 131 | 30 | 48 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. | 34 | Q95JH7 | 323 | AK1C1_MACFA Aldo-keto reductase family 1 memb... | 307 | 6e-34 | 130 | 31 | 47 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 35 | Q6Y0Z3 | 324 | XYL1_CANPA NADH-dependent D-xylose reductase ... | 298 | 1e-33 | 130 | 32 | 50 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 36 | Q54NZ7 | 311 | ALRB_DICDI Aldose reductase B OS=Dictyosteliu... | 303 | 2e-33 | 129 | 30 | 51 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase. | | | | | | | | | | | 37 | P51857 | 326 | AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen... | 301 | 2e-33 | 129 | 33 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB. | 38 | P80508 | 323 | PE2R_RABIT Prostaglandin-E(2) 9-reductase OS=... | 296 | 2e-33 | 129 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 39 | P51635 | 325 | AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=... | 290 | 3e-33 | 129 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 40 | Q6AYQ2 | 318 | AK1CL_RAT Aldo-keto reductase family 1 member... | 276 | 4e-33 | 128 | 34 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 41 | P87039 | 324 | XYL2_CANTR NADPH-dependent D-xylose reductase... | 298 | 5e-33 | 128 | 33 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 42 | Q5REQ0 | 323 | AK1C1_PONAB Aldo-keto reductase family 1 memb... | 303 | 5e-33 | 128 | 30 | 48 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 43 | P50578 | 325 | AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=... | 290 | 6e-33 | 128 | 31 | 52 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 44 | O42888 | 325 | YBN4_SCHPO Uncharacterized oxidoreductase C8E... | 292 | 6e-33 | 128 | 31 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 45 | Q9JII6 | 325 | AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O... | 290 | 7e-33 | 128 | 32 | 51 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI. | | | | | | | | | | GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI. | 46 | O80944 | 311 | AKRC8_ARATH Aldo-keto reductase family 4 memb... | 275 | 8e-33 | 127 | 34 | 52 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 47 | Q1XAA8 | 322 | AK1CN_HORSE Aldo-keto reductase family 1 memb... | 293 | 8e-33 | 127 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 48 | Q8K023 | 323 | AKC1H_MOUSE Aldo-keto reductase family 1 memb... | 290 | 9e-33 | 127 | 31 | 48 | | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0007567; P:parturition; IMP:MGI.::GO:0006709; P:progesterone catabolic process; IDA:MGI. | 49 | P23457 | 322 | DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase... | 301 | 1e-32 | 127 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC. | | | | | | | | | | GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD. | 50 | P14550 | 325 | AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O... | 287 | 2e-32 | 127 | 33 | 51 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc. | 51 | O13283 | 324 | XYL1_CANTR NAD(P)H-dependent D-xylose reducta... | 298 | 2e-32 | 126 | 33 | 48 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 52 | Q8VC28 | 323 | AK1CD_MOUSE Aldo-keto reductase family 1 memb... | 295 | 3e-32 | 126 | 32 | 52 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006805; P:xenobiotic metabolic process; TAS:MGI. | 53 | O32210 | 276 | GR_BACSU Glyoxal reductase OS=Bacillus subtil... | 268 | 6e-32 | 124 | 35 | 56 | | | | | | | | | | | GO:0043892; F:methylglyoxal reductase (NADPH-dependent) activity; IEA:EC. | | | | | | | | | | | 54 | P27800 | 323 | ALDX_SPOSA Aldehyde reductase 1 OS=Sporobolom... | 301 | 7e-32 | 125 | 33 | 51 | GO:0005623; C:cell; IDA:UniProtKB. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB. | | | | | | | | | | | 55 | Q6IMN8 | 297 | ALRA_DICDI Aldose reductase A OS=Dictyosteliu... | 288 | 7e-32 | 125 | 32 | 50 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0042593; P:glucose homeostasis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IMP:dictyBase. | 56 | Q9TV64 | 326 | AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen... | 297 | 7e-32 | 125 | 31 | 48 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 57 | P06632 | 278 | DKGA_CORSC 2,5-diketo-D-gluconic acid reducta... | 275 | 7e-32 | 124 | 34 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 58 | Q0PGJ6 | 315 | AKRC9_ARATH Aldo-keto reductase family 4 memb... | 290 | 1e-31 | 124 | 33 | 50 | GO:0009507; C:chloroplast; IDA:TAIR. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 59 | Q3ZCJ2 | 325 | AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O... | 290 | 1e-31 | 124 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 60 | Q6AZW2 | 324 | A1A1A_DANRE Alcohol dehydrogenase [NADP(+)] A... | 275 | 3e-31 | 123 | 30 | 48 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 61 | A0QV10 | 275 | Y2408_MYCS2 Uncharacterized oxidoreductase MS... | 268 | 5e-31 | 122 | 34 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |