| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O59768 | 412 | VCX1_SCHPO Vacuolar calcium ion transporter O... | 374 | 1e-100 | 312 | 46 | 66 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000324; C:fungal-type vacuole; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015085; F:calcium ion transmembrane transporter activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IMP:PomBase. | 2 | Q99385 | 411 | VCX1_YEAST Vacuolar calcium ion transporter O... | 423 | 4e-96 | 300 | 44 | 63 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015369; F:calcium:hydrogen antiporter activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015386; F:potassium:hydrogen antiporter activity; IMP:SGD. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IMP:SGD. | 3 | Q6K1C4 | 417 | CAX3_ORYSJ Vacuolar cation/proton exchanger 3... | 380 | 2e-82 | 265 | 41 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 4 | Q39254 | 441 | CAX2_ARATH Vacuolar cation/proton exchanger 2... | 379 | 1e-80 | 261 | 39 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR. | | | | | | | | | | GO:0015369; F:calcium:hydrogen antiporter activity; IDA:TAIR. | | | | | | | | | | GO:0015691; P:cadmium ion transport; IGI:TAIR.::GO:0006828; P:manganese ion transport; IGI:TAIR. | 5 | Q8L783 | 441 | CAX5_ARATH Vacuolar cation/proton exchanger 5... | 379 | 4e-80 | 260 | 39 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 6 | Q5KQN0 | 437 | CAX2_ORYSJ Vacuolar cation/proton exchanger 2... | 379 | 4e-80 | 259 | 41 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 7 | Q9LFZ8 | 448 | CAX6_ARATH Putative vacuolar cation/proton ex... | 380 | 1e-73 | 243 | 39 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 8 | Q945S5 | 446 | CAX4_ARATH Vacuolar cation/proton exchanger 4... | 381 | 7e-71 | 236 | 38 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR. | | | | | | | | | | GO:0015369; F:calcium:hydrogen antiporter activity; IMP:TAIR. | | | | | | | | | | GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR. | 9 | Q39253 | 463 | CAX1_ARATH Vacuolar cation/proton exchanger 1... | 383 | 2e-68 | 230 | 38 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR. | | | | | | | | | | GO:0015369; F:calcium:hydrogen antiporter activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030026; P:cellular manganese ion homeostasis; IMP:TAIR.::GO:0006882; P:cellular zinc ion homeostasis; IMP:TAIR.::GO:0009631; P:cold acclimation; IMP:TAIR.::GO:0055062; P:phosphate ion homeostasis; IGI:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR. | 10 | Q5TKG3 | 453 | CAX1B_ORYSJ Vacuolar cation/proton exchanger ... | 365 | 9e-65 | 220 | 37 | 61 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 11 | Q769E5 | 451 | CAX1A_ORYSJ Vacuolar cation/proton exchanger ... | 385 | 2e-63 | 216 | 37 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 12 | Q93Z81 | 459 | CAX3_ARATH Vacuolar cation/proton exchanger 3... | 383 | 5e-61 | 210 | 35 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR. | | | | | | | | | | GO:0015369; F:calcium:hydrogen antiporter activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IGI:TAIR.::GO:0030026; P:cellular manganese ion homeostasis; IGI:TAIR.::GO:0006882; P:cellular zinc ion homeostasis; IGI:TAIR.::GO:0010351; P:lithium ion transport; IGI:TAIR.::GO:0055062; P:phosphate ion homeostasis; IGI:TAIR.::GO:0006793; P:phosphorus metabolic process; IGI:TAIR.::GO:0051592; P:response to calcium ion; IMP:TAIR.::GO:0009624; P:response to nematode; IEP:TAIR.::GO:0006814; P:sodium ion transport; IGI:TAIR. | 13 | Q6YXZ1 | 447 | CAX4_ORYSJ Putative vacuolar cation/proton ex... | 386 | 7e-61 | 209 | 35 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW. | 14 | O34840 | 351 | YFKE_BACSU Putative cation exchanger yfkE OS=... | 359 | 2e-58 | 200 | 35 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | | 15 | Q5KTQ9 | 450 | CAX1C_ORYSJ Vacuolar cation/proton exchanger ... | 384 | 3e-47 | 173 | 34 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 16 | P42839 | 908 | VNX1_YEAST Low affinity vacuolar monovalent c... | 400 | 1e-23 | 107 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015369; F:calcium:hydrogen antiporter activity; IMP:SGD.::GO:0015386; F:potassium:hydrogen antiporter activity; IMP:SGD.::GO:0015385; F:sodium:hydrogen antiporter activity; IMP:SGD. | | | | | | | | | | | 17 | Q9P7B3 | 881 | YI14_SCHPO Putative cation exchanger C521.04c... | 185 | 0.000000002 | 63.5 | 25 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; IEA:InterPro. | 18 | P55471 | 367 | Y4HA_RHISN Putative ionic transporter y4hA OS... | 270 | 0.0000002 | 56.6 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | | 19 | Q99PD7 | 645 | NCKX3_MOUSE Sodium/potassium/calcium exchange... | 179 | 0.0001 | 47.8 | 23 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:MGI. | | | | | | | | | | GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:MGI.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; TAS:MGI. | 20 | Q9EPQ0 | 624 | NCKX3_RAT Sodium/potassium/calcium exchanger ... | 179 | 0.0001 | 47.8 | 23 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:RGD.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IEP:RGD. | 21 | Q9HC58 | 644 | NCKX3_HUMAN Sodium/potassium/calcium exchange... | 182 | 0.0008 | 45.4 | 24 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | Q8NFF2 | 622 | NCKX4_HUMAN Sodium/potassium/calcium exchange... | 125 | 0.003 | 43.5 | 25 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. | 23 | Q8CGQ8 | 622 | NCKX4_MOUSE Sodium/potassium/calcium exchange... | 125 | 0.017 | 41.2 | 24 | 50 | GO:0005887; C:integral to plasma membrane; IC:MGI. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. | 24 | P31801 | 366 | CHAA_ECOLI Calcium/proton antiporter OS=Esche... | 232 | 0.048 | 39.3 | 20 | 43 | GO:0005887; C:integral to plasma membrane; IDA:EcoliWiki. | | | | | | | | | | GO:0015386; F:potassium:hydrogen antiporter activity; IDA:EcoCyc.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:EcoCyc. | | | | | | | | | | GO:0030007; P:cellular potassium ion homeostasis; IGI:EcoCyc.::GO:0006883; P:cellular sodium ion homeostasis; IGI:EcoCyc. | 25 | Q49SH1 | 513 | NCKX5_DANRE Sodium/potassium/calcium exchange... | 132 | 1.5 | 34.7 | 23 | 47 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. | 26 | Q57556 | 302 | Y091_METJA Uncharacterized membrane protein M... | 124 | 3.4 | 33.5 | 27 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0055085; P:transmembrane transport; IEA:InterPro. | 27 | Q8C261 | 501 | NCKX5_MOUSE Sodium/potassium/calcium exchange... | 57 | 3.7 | 33.5 | 37 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. | 28 | O43520 | 1251 | AT8B1_HUMAN Probable phospholipid-transportin... | 87 | 4.4 | 33.5 | 26 | 40 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015662; F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004012; F:phospholipid-translocating ATPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0015721; P:bile acid and bile salt transport; NAS:UniProtKB.::GO:0006812; P:cation transport; IEA:InterPro.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045332; P:phospholipid translocation; NAS:UniProtKB. | 29 | Q9LJI2 | 643 | CCX3_ARATH Cation/calcium exchanger 3 OS=Arab... | 69 | 5.8 | 33.1 | 29 | 52 | GO:0030659; C:cytoplasmic vesicle membrane; IDA:TAIR.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005384; F:manganese ion transmembrane transporter activity; IMP:TAIR.::GO:0015079; F:potassium ion transmembrane transporter activity; IMP:TAIR.::GO:0015081; F:sodium ion transmembrane transporter activity; IMP:TAIR. | | | | | | | | | | GO:0030003; P:cellular cation homeostasis; IDA:TAIR.::GO:0043157; P:response to cation stress; IEP:TAIR. | 30 | Q9SYG9 | 644 | CCX4_ARATH Cation/calcium exchanger 4 OS=Arab... | 69 | 6.3 | 32.7 | 29 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015297; F:antiporter activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. |
