rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P11710 | 512 | FUS1_YEAST Nuclear fusion protein FUS1 OS=Sac... | 76 | 0.001 | 43.9 | 32 | 47 | GO:0005938; C:cell cortex; IMP:GOC.::GO:0005887; C:integral to plasma membrane; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032065; P:cortical protein anchoring; IMP:SGD.::GO:0000755; P:cytogamy; IMP:SGD.::GO:0031385; P:regulation of termination of mating projection growth; IMP:SGD. | 2 | Q8IVI9 | 506 | NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ... | 69 | 0.23 | 37 | 29 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 3 | Q96DR7 | 871 | ARHGQ_HUMAN Rho guanine nucleotide exchange f... | 56 | 0.25 | 37 | 30 | 52 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 4 | O57604 | 571 | PODXL_CHICK Podocalyxin OS=Gallus gallus (Chi... | 81 | 0.38 | 36.2 | 28 | 47 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0031528; C:microvillus membrane; IDA:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0072175; P:epithelial tube formation; ISS:UniProtKB.::GO:0022408; P:negative regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0033634; P:positive regulation of cell-cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0032534; P:regulation of microvillus assembly; IDA:UniProtKB. | 5 | Q1JPB0 | 377 | ILEU_BOVIN Leukocyte elastase inhibitor OS=Bo... | 70 | 0.55 | 35.8 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004867; F:serine-type endopeptidase inhibitor activity; ISS:RefGenome. | | | | | | | | | | GO:0030162; P:regulation of proteolysis; ISS:RefGenome. | 6 | P05619 | 379 | ILEU_HORSE Leukocyte elastase inhibitor OS=Eq... | 55 | 1.2 | 34.7 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | O60939 | 215 | SCN2B_HUMAN Sodium channel subunit beta-2 OS=... | 47 | 1.2 | 33.9 | 34 | 57 | GO:0001518; C:voltage-gated sodium channel complex; TAS:UniProtKB. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0090072; P:positive regulation of sodium ion transport via voltage-gated sodium channel activity; TAS:BHF-UCL.::GO:0007268; P:synaptic transmission; TAS:ProtInc. | 8 | Q864L3 | 215 | SCN2B_CANFA Sodium channel subunit beta-2 OS=... | 36 | 2.1 | 33.5 | 39 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | O75962 | 3097 | TRIO_HUMAN Triple functional domain protein O... | 81 | 2.2 | 34.3 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 10 | Q0KL02 | 3102 | TRIO_MOUSE Triple functional domain protein O... | 81 | 2.5 | 33.9 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 11 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 106 | 2.5 | 33.9 | 27 | 42 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q56A07 | 215 | SCN2B_MOUSE Sodium channel subunit beta-2 OS=... | 36 | 2.6 | 33.1 | 39 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 13 | P54900 | 215 | SCN2B_RAT Sodium channel subunit beta-2 OS=Ra... | 36 | 3 | 32.7 | 39 | 64 | GO:0001518; C:voltage-gated sodium channel complex; TAS:RGD. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; IDA:RGD. | | | | | | | | | | GO:0007399; P:nervous system development; IEP:RGD.::GO:0046684; P:response to pyrethroid; IDA:RGD. | 14 | Q058B2 | 376 | DAPE_BUCCC Succinyl-diaminopimelate desucciny... | 65 | 6 | 32.3 | 34 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:InterPro.::GO:0009014; F:succinyl-diaminopimelate desuccinylase activity; IEA:EC. | | | | | | | | | | GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 15 | P97924 | 2959 | KALRN_RAT Kalirin OS=Rattus norvegicus (Rat).... | 99 | 6.2 | 32.7 | 28 | 44 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007409; P:axonogenesis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:HGNC.::GO:0050773; P:regulation of dendrite development; IDA:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 16 | Q5I0D6 | 502 | NOSTN_RAT Nostrin OS=Rattus norvegicus (Rat).... | 52 | 7.2 | 32.3 | 33 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 17 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 36 | 8.2 | 32.3 | 36 | 50 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 18 | A2CG49 | 2964 | KALRN_MOUSE Kalirin OS=Mus musculus (Mouse). ... | 99 | 9.1 | 32.3 | 28 | 44 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 19 | Q10199 | 670 | IMP2_SCHPO Septation protein imp2 OS=Schizosa... | 79 | 10 | 32 | 20 | 47 | GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. |