| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P09741 | 301 | TNNT2_RABIT Troponin T, cardiac muscle OS=Ory... | 84 | 0.13 | 36.6 | 38 | 54 | GO:0005861; C:troponin complex; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0005523; F:tropomyosin binding; ISS:UniProtKB.::GO:0030172; F:troponin C binding; ISS:UniProtKB.::GO:0031013; F:troponin I binding; ISS:UniProtKB. | | | | | | | | | | GO:0030049; P:muscle filament sliding; ISS:UniProtKB.::GO:0032780; P:negative regulation of ATPase activity; ISS:UniProtKB.::GO:0032781; P:positive regulation of ATPase activity; ISS:UniProtKB.::GO:0008016; P:regulation of heart contraction; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB. | 2 | P45379 | 298 | TNNT2_HUMAN Troponin T, cardiac muscle OS=Hom... | 84 | 0.14 | 36.6 | 38 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005861; C:troponin complex; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0005523; F:tropomyosin binding; IDA:UniProtKB.::GO:0030172; F:troponin C binding; IPI:UniProtKB.::GO:0031013; F:troponin I binding; IPI:UniProtKB. | | | | | | | | | | GO:0006200; P:ATP catabolic process; IDA:GOC.::GO:0030049; P:muscle filament sliding; IDA:UniProtKB.::GO:0032780; P:negative regulation of ATPase activity; IDA:UniProtKB.::GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.::GO:0008016; P:regulation of heart contraction; IMP:UniProtKB.::GO:0051592; P:response to calcium ion; IMP:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL. | 3 | P50752 | 301 | TNNT2_MOUSE Troponin T, cardiac muscle OS=Mus... | 84 | 0.32 | 35.4 | 38 | 52 | GO:0005861; C:troponin complex; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; IDA:MGI.::GO:0005523; F:tropomyosin binding; ISS:UniProtKB.::GO:0030172; F:troponin C binding; ISS:UniProtKB.::GO:0031013; F:troponin I binding; ISS:UniProtKB. | | | | | | | | | | GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IMP:MGI.::GO:0030049; P:muscle filament sliding; ISS:UniProtKB.::GO:0032780; P:negative regulation of ATPase activity; ISS:UniProtKB.::GO:0032781; P:positive regulation of ATPase activity; ISS:UniProtKB.::GO:0008016; P:regulation of heart contraction; IMP:MGI.::GO:0051592; P:response to calcium ion; ISS:UniProtKB.::GO:0045214; P:sarcomere organization; IMP:MGI.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI. | 4 | P21802 | 821 | FGFR2_HUMAN Fibroblast growth factor receptor... | 55 | 0.51 | 35.4 | 40 | 49 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.::GO:0045165; P:cell fate commitment; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; ISS:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; ISS:UniProtKB.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; ISS:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; ISS:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; ISS:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0032808; P:lacrimal gland development; ISS:UniProtKB.::GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0048286; P:lung alveolus development; ISS:UniProtKB.::GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.::GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.::GO:0060615; P:mammary gland bud formation; ISS:UniProtKB.::GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.::GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0035264; P:multicellular organism growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0035265; P:organ growth; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.::GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0021860; P:pyramidal neuron development; ISS:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.::GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; TAS:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; TAS:UniProtKB.::GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB.::GO:0021847; P:ventricular zone neuroblast division; ISS:UniProtKB. | 5 | Q9S7C9 | 311 | ESCA_ARATH Putative DNA-binding protein ESCAR... | 29 | 0.56 | 35 | 62 | 69 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0003680; F:AT DNA binding; IDA:TAIR.::GO:0003690; F:double-stranded DNA binding; IDA:TAIR. | | | | | | | | | | GO:0006325; P:chromatin organization; IMP:TAIR.::GO:0010150; P:leaf senescence; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IMP:TAIR. | 6 | P50751 | 287 | TNNT2_SHEEP Troponin T, cardiac muscle OS=Ovi... | 85 | 1.5 | 33.5 | 40 | 55 | | | | | | | | | | | | | | | | | | | | | | 7 | Q21QM5 | 469 | MNME_RHOFD tRNA modification GTPase MnmE OS=R... | 81 | 1.9 | 33.5 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006400; P:tRNA modification; IEA:InterPro. | 8 | Q8K585 | 107 | HMGA1_RAT High mobility group protein HMG-I/H... | 20 | 2.5 | 31.6 | 80 | 80 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0035985; C:senescence-associated heterochromatin focus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090402; P:oncogene-induced senescence; ISS:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | P17095 | 107 | HMGA1_MOUSE High mobility group protein HMG-I... | 20 | 2.8 | 31.2 | 80 | 80 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0035985; C:senescence-associated heterochromatin focus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090402; P:oncogene-induced senescence; ISS:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q9QXP3 | 107 | HMGA1_CRIGR High mobility group protein HMG-I... | 20 | 2.9 | 31.2 | 80 | 80 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0035985; C:senescence-associated heterochromatin focus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090402; P:oncogene-induced senescence; ISS:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | P17096 | 107 | HMGA1_HUMAN High mobility group protein HMG-I... | 18 | 2.9 | 31.2 | 83 | 83 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0035985; C:senescence-associated heterochromatin focus; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; TAS:UniProtKB. | | | | | | | | | | GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; IDA:UniProtKB.::GO:0003680; F:AT DNA binding; TAS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0046965; F:retinoid X receptor binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0006268; P:DNA unwinding involved in replication; NAS:UniProtKB.::GO:0019059; P:initiation of viral infection; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0031936; P:negative regulation of chromatin silencing; TAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006337; P:nucleosome disassembly; TAS:UniProtKB.::GO:0090402; P:oncogene-induced senescence; IDA:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; IMP:UniProtKB.::GO:0006461; P:protein complex assembly; TAS:UniProtKB.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q6URC2 | 107 | HMGA1_CANFA High mobility group protein HMG-I... | 18 | 2.9 | 31.2 | 83 | 83 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0035985; C:senescence-associated heterochromatin focus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090402; P:oncogene-induced senescence; ISS:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | P52927 | 108 | HMGA2_MOUSE High mobility group protein HMGI-... | 19 | 3.1 | 31.2 | 79 | 84 | GO:0000228; C:nuclear chromosome; IDA:MGI.::GO:0032993; C:protein-DNA complex; ISS:UniProtKB.::GO:0035985; C:senescence-associated heterochromatin focus; ISS:UniProtKB.::GO:0071141; C:SMAD protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; ISS:UniProtKB.::GO:0003680; F:AT DNA binding; ISS:UniProtKB.::GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0035497; F:cAMP response element binding; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0008301; F:DNA binding, bending; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; ISS:UniProtKB.::GO:0004677; F:DNA-dependent protein kinase activity; ISS:UniProtKB.::GO:0035501; F:MH1 domain binding; ISS:UniProtKB.::GO:0035500; F:MH2 domain binding; ISS:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI. | | | | | | | | | | GO:0030325; P:adrenal gland development; IMP:MGI.::GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021846; P:cell proliferation in forebrain; IMP:MGI.::GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.::GO:0035988; P:chondrocyte proliferation; ISS:UniProtKB.::GO:0031052; P:chromosome breakage; ISS:UniProtKB.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.::GO:0035987; P:endodermal cell differentiation; ISS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; ISS:UniProtKB.::GO:0060613; P:fat pad development; IGI:MGI.::GO:0035978; P:histone H2A-S139 phosphorylation; ISS:UniProtKB.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0048333; P:mesodermal cell differentiation; ISS:UniProtKB.::GO:0003131; P:mesodermal-endodermal cell signaling; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0043922; P:negative regulation by host of viral transcription; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0048712; P:negative regulation of astrocyte differentiation; IDA:MGI.::GO:0043392; P:negative regulation of DNA binding; ISS:UniProtKB.::GO:2001033; P:negative regulation of double-strand break repair via nonhomologous end joining; ISS:UniProtKB.::GO:0045869; P:negative regulation of retroviral genome replication; ISS:UniProtKB.::GO:0090402; P:oncogene-induced senescence; ISS:UniProtKB.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.::GO:2000685; P:positive regulation of cellular response to X-ray; ISS:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; ISS:UniProtKB.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:MGI.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:2001038; P:regulation of cellular response to drug; ISS:UniProtKB.::GO:0060123; P:regulation of growth hormone secretion; IMP:MGI.::GO:2000036; P:regulation of stem cell maintenance; ISS:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 14 | P13789 | 285 | TNNT2_BOVIN Troponin T, cardiac muscle OS=Bos... | 84 | 3.4 | 32.3 | 38 | 52 | | | | | | | | | | | | | | | | | | | | | | 15 | P50753 | 299 | TNNT2_RAT Troponin T, cardiac muscle OS=Rattu... | 84 | 3.5 | 32.3 | 38 | 54 | GO:0005861; C:troponin complex; IDA:RGD. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0030674; F:protein binding, bridging; IDA:RGD.::GO:0005523; F:tropomyosin binding; ISS:UniProtKB.::GO:0030172; F:troponin C binding; ISS:UniProtKB.::GO:0031013; F:troponin I binding; IPI:RGD. | | | | | | | | | | GO:0051764; P:actin crosslink formation; IDA:RGD.::GO:0030049; P:muscle filament sliding; ISS:UniProtKB.::GO:0032780; P:negative regulation of ATPase activity; ISS:UniProtKB.::GO:0032781; P:positive regulation of ATPase activity; ISS:UniProtKB.::GO:0008016; P:regulation of heart contraction; ISS:UniProtKB.::GO:0032972; P:regulation of muscle filament sliding speed; IMP:BHF-UCL.::GO:0051592; P:response to calcium ion; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB. | 16 | P52926 | 109 | HMGA2_HUMAN High mobility group protein HMGI-... | 19 | 5.1 | 30.4 | 79 | 84 | GO:0000228; C:nuclear chromosome; ISS:UniProtKB.::GO:0032993; C:protein-DNA complex; IDA:UniProtKB.::GO:0035985; C:senescence-associated heterochromatin focus; IDA:UniProtKB.::GO:0071141; C:SMAD protein complex; IDA:UniProtKB. | | | | | | | | | | GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; IDA:UniProtKB.::GO:0003680; F:AT DNA binding; IDA:UniProtKB.::GO:0070742; F:C2H2 zinc finger domain binding; IMP:UniProtKB.::GO:0035497; F:cAMP response element binding; IDA:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0008301; F:DNA binding, bending; IDA:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0004677; F:DNA-dependent protein kinase activity; IDA:UniProtKB.::GO:0035501; F:MH1 domain binding; IDA:UniProtKB.::GO:0035500; F:MH2 domain binding; IDA:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0002062; P:chondrocyte differentiation; IDA:UniProtKB.::GO:0035988; P:chondrocyte proliferation; IDA:UniProtKB.::GO:0031052; P:chromosome breakage; IDA:UniProtKB.::GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.::GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.::GO:0035987; P:endodermal cell differentiation; IMP:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0045444; P:fat cell differentiation; IMP:UniProtKB.::GO:0035978; P:histone H2A-S139 phosphorylation; IDA:UniProtKB.::GO:0048333; P:mesodermal cell differentiation; IMP:UniProtKB.::GO:0003131; P:mesodermal-endodermal cell signaling; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.::GO:2001033; P:negative regulation of double-strand break repair via nonhomologous end joining; IDA:UniProtKB.::GO:0045869; P:negative regulation of retroviral genome replication; IDA:UniProtKB.::GO:0090402; P:oncogene-induced senescence; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:2000685; P:positive regulation of cellular response to X-ray; IDA:UniProtKB.::GO:2000774; P:positive regulation of cellular senescence; IMP:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; IDA:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IDA:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:UniProtKB.::GO:2001038; P:regulation of cellular response to drug; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:2000036; P:regulation of stem cell maintenance; IMP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0035986; P:senescence-associated heterochromatin focus assembly; IDA:UniProtKB.::GO:0048863; P:stem cell differentiation; IEP:UniProtKB. | 17 | P21803 | 821 | FGFR2_MOUSE Fibroblast growth factor receptor... | 55 | 5.7 | 32 | 36 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IMP:UniProtKB.::GO:0005576; C:extracellular region; TAS:MGI.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:MGI.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IGI:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0030282; P:bone mineralization; IMP:MGI.::GO:0060349; P:bone morphogenesis; IMP:MGI.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; IMP:MGI.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; IMP:MGI.::GO:0048755; P:branching morphogenesis of a nerve; IMP:MGI.::GO:0060449; P:bud elongation involved in lung branching; IMP:MGI.::GO:0045165; P:cell fate commitment; IDA:MGI.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0009880; P:embryonic pattern specification; IMP:MGI.::GO:0061031; P:endodermal digestive tract morphogenesis; IMP:MGI.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IMP:MGI.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; IMP:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; IMP:MGI.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; IMP:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; IMP:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; IMP:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0032808; P:lacrimal gland development; IMP:MGI.::GO:0060601; P:lateral sprouting from an epithelium; IMP:MGI.::GO:0070307; P:lens fiber cell development; IGI:MGI.::GO:0060174; P:limb bud formation; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0060463; P:lung lobe morphogenesis; IMP:MGI.::GO:0060484; P:lung-associated mesenchyme development; IMP:MGI.::GO:0060615; P:mammary gland bud formation; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; IGI:MGI.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; IMP:MGI.::GO:0030901; P:midbrain development; IGI:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0045839; P:negative regulation of mitosis; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0042476; P:odontogenesis; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0030916; P:otic vesicle formation; IMP:MGI.::GO:0003148; P:outflow tract septum morphogenesis; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051781; P:positive regulation of cell division; IMP:MGI.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IMP:MGI.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IGI:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IMP:MGI.::GO:0060523; P:prostate epithelial cord elongation; IMP:MGI.::GO:0021860; P:pyramidal neuron development; IMP:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IMP:MGI.::GO:0010453; P:regulation of cell fate commitment; IMP:MGI.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IMP:MGI.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0051150; P:regulation of smooth muscle cell differentiation; IMP:MGI.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; IMP:MGI.::GO:0048489; P:synaptic vesicle transport; IMP:MGI.::GO:0001657; P:ureteric bud development; IGI:MGI.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI.::GO:0021847; P:ventricular zone neuroblast division; IMP:UniProtKB. | 18 | O33600 | 886 | RAD50_SULAC DNA double-strand break repair Ra... | 122 | 8.4 | 31.6 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. |
