rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | Q09517 | 316 | LE767_CAEEL Putative steroid dehydrogenase le... | 200 | 0.0002 | 45.8 | 27 | 45 | GO:0045179; C:apical cortex; IDA:WormBase.::GO:0005783; C:endoplasmic reticulum; IDA:WormBase. | | | | | | | | | | GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008210; P:estrogen metabolic process; IMP:WormBase.::GO:0030540; P:female genitalia development; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0032350; P:regulation of hormone metabolic process; IMP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IDA:WormBase. | 452 | O74959 | 339 | YJCD_SCHPO Uncharacterized oxidoreductase C73... | 214 | 0.0003 | 45.4 | 21 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 453 | Q8VBZ0 | 335 | DHRSX_MOUSE Dehydrogenase/reductase SDR famil... | 115 | 0.0003 | 45.4 | 33 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 454 | Q0THM2 | 240 | FOLM_ECOL5 Dihydrofolate reductase folM OS=Es... | 183 | 0.0003 | 45.1 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 455 | Q8FHB1 | 240 | FOLM_ECOL6 Dihydrofolate reductase folM OS=Es... | 183 | 0.0003 | 44.7 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 456 | A6SG70 | 331 | MKAR_BOTFB 3-ketoacyl-CoA reductase OS=cinere... | 282 | 0.0004 | 45.1 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 457 | P70385 | 305 | DHB3_MOUSE Testosterone 17-beta-dehydrogenase... | 181 | 0.0004 | 45.1 | 25 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 458 | Q1RBJ2 | 240 | FOLM_ECOUT Dihydrofolate reductase folM OS=Es... | 183 | 0.0004 | 44.7 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 459 | A1ABF1 | 240 | FOLM_ECOK1 Dihydrofolate reductase folM OS=Es... | 183 | 0.0004 | 44.7 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 460 | O08699 | 266 | PGDH_RAT 15-hydroxyprostaglandin dehydrogenas... | 205 | 0.0004 | 44.7 | 29 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 461 | A8AGY5 | 240 | FOLM_CITK8 Dihydrofolate reductase folM OS=Ci... | 187 | 0.0004 | 44.7 | 27 | 44 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 462 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 203 | 0.0004 | 44.7 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 463 | Q3ZBV9 | 255 | DHR11_BOVIN Dehydrogenase/reductase SDR famil... | 195 | 0.0005 | 44.3 | 24 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 464 | Q6P5L8 | 415 | HSDL2_DANRE Hydroxysteroid dehydrogenase-like... | 179 | 0.0006 | 44.7 | 30 | 47 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 465 | Q32G72 | 240 | FOLM_SHIDS Dihydrofolate reductase folM OS=Sh... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 466 | P0AFS3 | 240 | FOLM_ECOLI Dihydrofolate reductase folM OS=Es... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IDA:EcoliWiki.::GO:0071172; F:dihydromonapterin reductase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009257; P:10-formyltetrahydrofolate biosynthetic process; IMP:EcoliWiki.::GO:0046656; P:folic acid biosynthetic process; IMP:EcoliWiki.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 467 | B1IQY4 | 240 | FOLM_ECOLC Dihydrofolate reductase folM OS=Es... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 468 | A8A0E8 | 240 | FOLM_ECOHS Dihydrofolate reductase folM OS=Es... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 469 | P0AFS4 | 240 | FOLM_ECO57 Dihydrofolate reductase folM OS=Es... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 470 | O54939 | 306 | DHB3_RAT Testosterone 17-beta-dehydrogenase 3... | 181 | 0.0006 | 44.3 | 25 | 46 | GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD. | 471 | A7ZM66 | 240 | FOLM_ECO24 Dihydrofolate reductase folM OS=Es... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 472 | Q3Z1V9 | 240 | FOLM_SHISS Dihydrofolate reductase folM OS=Sh... | 183 | 0.0006 | 43.9 | 24 | 45 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 473 | Q8K354 | 277 | CBR3_MOUSE Carbonyl reductase [NADPH] 3 OS=Mu... | 151 | 0.0007 | 43.9 | 28 | 44 | | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 474 | Q0VFE7 | 309 | DRS7B_XENTR Dehydrogenase/reductase SDR famil... | 210 | 0.0007 | 43.9 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 475 | Q6BIG0 | 346 | MKAR_DEBHA 3-ketoacyl-CoA reductase OS=0083 /... | 210 | 0.0008 | 44.3 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 476 | P0CR37 | 335 | TSC10_CRYNB 3-ketodihydrosphingosine reductas... | 177 | 0.0008 | 43.9 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 477 | B5Z114 | 270 | HCAB_ECO5E 3-phenylpropionate-dihydrodiol/cin... | 167 | 0.0008 | 43.9 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 478 | Q8XA72 | 270 | HCAB_ECO57 3-phenylpropionate-dihydrodiol/cin... | 167 | 0.0008 | 43.9 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 479 | P0CR36 | 335 | TSC10_CRYNJ 3-ketodihydrosphingosine reductas... | 177 | 0.0009 | 43.9 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 480 | Q0U3N7 | 341 | MKAR_PHANO 3-ketoacyl-CoA reductase OS=(Glume... | 205 | 0.0009 | 43.9 | 23 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 481 | Q31XU9 | 270 | HCAB_SHIBS 3-phenylpropionate-dihydrodiol/cin... | 167 | 0.001 | 43.5 | 26 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. |