rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | O01498 | 457 | STAM1_CAEEL Signal transducing adapter molecu... | 120 | 0.0000000002 | 67 | 28 | 55 | GO:0044441; C:cilium part; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0033565; C:ESCRT-0 complex; IPI:WormBase. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:WormBase.::GO:0043130; F:ubiquitin binding; IDA:WormBase. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:WormBase.::GO:0048013; P:ephrin receptor signaling pathway; IGI:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB. | 92 | Q80U44 | 1528 | ZFY16_MOUSE Zinc finger FYVE domain-containin... | 75 | 0.0000000003 | 67.8 | 40 | 59 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 93 | Q2KIY3 | 410 | WDFY1_BOVIN WD repeat and FYVE domain-contain... | 114 | 0.0000000005 | 65.9 | 34 | 49 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 94 | Q8IWB7 | 410 | WDFY1_HUMAN WD repeat and FYVE domain-contain... | 114 | 0.0000000005 | 65.9 | 34 | 49 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | | 95 | Q5UR69 | 701 | YL615_MIMIV Putative phosphatidylinositol kin... | 99 | 0.000000001 | 65.5 | 30 | 46 | | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 96 | Q8IZQ1 | 3526 | WDFY3_HUMAN WD repeat and FYVE domain-contain... | 66 | 0.000000001 | 65.9 | 42 | 53 | GO:0044444; C:cytoplasmic part; IDA:MGI.::GO:0019898; C:extrinsic to membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 97 | Q6VNB8 | 3508 | WDFY3_MOUSE WD repeat and FYVE domain-contain... | 66 | 0.000000001 | 65.9 | 42 | 53 | | | | | | | | | | | GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 98 | Q6C2N2 | 685 | HSE1_YARLI Class E vacuolar protein-sorting m... | 54 | 0.6 | 37 | 30 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 99 | Q8BL66 | 1411 | EEA1_MOUSE Early endosome antigen 1 OS=Mus mu... | 60 | 0.000000002 | 65.1 | 45 | 62 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0005969; C:serine-pyruvate aminotransferase complex; IDA:MGI. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB. | 100 | Q15075 | 1411 | EEA1_HUMAN Early endosome antigen 1 OS=Homo s... | 60 | 0.000000002 | 64.7 | 45 | 62 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:UniProtKB. | | | | | | | | | | GO:0045022; P:early endosome to late endosome transport; NAS:UniProtKB.::GO:0016189; P:synaptic vesicle to endosome fusion; TAS:UniProtKB.::GO:0006906; P:vesicle fusion; IMP:UniProtKB. | 101 | O95405 | 1425 | ZFYV9_HUMAN Zinc finger FYVE domain-containin... | 89 | 0.000000002 | 64.7 | 37 | 55 | GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.::GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB. | 102 | Q05B78 | 254 | ZFY21_BOVIN Zinc finger FYVE domain-containin... | 74 | 0.000000003 | 61.6 | 39 | 51 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 103 | Q6ZV73 | 1430 | FGD6_HUMAN FYVE, RhoGEF and PH domain-contain... | 77 | 0.000000005 | 63.5 | 40 | 56 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 104 | Q8VCM3 | 234 | ZFY21_MOUSE Zinc finger FYVE domain-containin... | 74 | 0.000000006 | 60.5 | 39 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 105 | D3ZVP7 | 234 | ZFY21_RAT Zinc finger FYVE domain-containing ... | 74 | 0.000000007 | 60.5 | 39 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 106 | Q5PQT2 | 1194 | MTMR3_RAT Myotubularin-related protein 3 OS=R... | 62 | 0.00000001 | 62.4 | 40 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB. | 107 | Q8K296 | 1196 | MTMR3_MOUSE Myotubularin-related protein 3 OS... | 62 | 0.00000001 | 62.4 | 40 | 58 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB. | 108 | Q13615 | 1198 | MTMR3_HUMAN Myotubularin-related protein 3 OS... | 62 | 0.00000001 | 62.4 | 40 | 58 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB. | 109 | Q69ZL1 | 1399 | FGD6_MOUSE FYVE, RhoGEF and PH domain-contain... | 114 | 0.00000001 | 62.4 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 110 | Q54LD5 | 785 | ADCD_DICDI Arrestin domain-containing protein... | 63 | 0.00000001 | 62 | 40 | 56 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 111 | Q5ZLY5 | 249 | PKHF2_CHICK Pleckstrin homology domain-contai... | 68 | 0.00000002 | 59.3 | 49 | 62 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 112 | Q06336 | 557 | GGA1_YEAST ADP-ribosylation factor-binding pr... | 128 | 0.00000002 | 61.2 | 30 | 55 | GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005802; C:trans-Golgi network; IDA:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD. | 113 | Q9BQ24 | 234 | ZFY21_HUMAN Zinc finger FYVE domain-containin... | 74 | 0.00000002 | 58.9 | 38 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 114 | B0G126 | 2656 | FYV1_DICDI 1-phosphatidylinositol 3-phosphate... | 56 | 0.00000003 | 61.2 | 46 | 59 | GO:0005739; C:mitochondrion; ISS:dictyBase. | | | | | | | | | | GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044267; P:cellular protein metabolic process; IEA:InterPro. | 115 | Q91WB4 | 249 | PKHF2_MOUSE Pleckstrin homology domain-contai... | 68 | 0.00000003 | 58.9 | 49 | 62 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 116 | Q9H8W4 | 249 | PKHF2_HUMAN Pleckstrin homology domain-contai... | 68 | 0.00000003 | 58.9 | 49 | 62 | GO:0030133; C:transport vesicle; IDA:LIFEdb. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 117 | Q54GH3 | 663 | TOM1_DICDI Target of Myb protein 1 OS=Dictyos... | 141 | 0.00000004 | 60.5 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 118 | Q7ZUV1 | 247 | PKHF2_DANRE Pleckstrin homology domain-contai... | 71 | 0.00000007 | 57.8 | 46 | 59 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 119 | Q6ZNL6 | 1462 | FGD5_HUMAN FYVE, RhoGEF and PH domain-contain... | 59 | 0.00000007 | 59.7 | 34 | 58 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 120 | Q91ZT5 | 766 | FGD4_MOUSE FYVE, RhoGEF and PH domain-contain... | 93 | 0.00000009 | 59.3 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030035; P:microspike assembly; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 121 | O88387 | 766 | FGD4_RAT FYVE, RhoGEF and PH domain-containin... | 93 | 0.0000001 | 58.9 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; IMP:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:MGI.::GO:0008360; P:regulation of cell shape; IMP:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |