rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q4P2W8 | 798 | DOT1_USTMA Histone-lysine N-methyltransferase... | 311 | 8e-60 | 212 | 39 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q1DKD8 | 499 | DOT1_COCIM Histone-lysine N-methyltransferase... | 237 | 1e-52 | 188 | 39 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | P0CN14 | 644 | DOT1_CRYNJ Histone-lysine N-methyltransferase... | 414 | 1e-51 | 187 | 34 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | P0CN15 | 644 | DOT1_CRYNB Histone-lysine N-methyltransferase... | 409 | 2e-51 | 187 | 34 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q2U696 | 335 | DOT1_ASPOR Histone-lysine N-methyltransferase... | 219 | 3e-50 | 177 | 38 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q5BH89 | 501 | DOT1_EMENI Histone-lysine N-methyltransferase... | 216 | 1e-49 | 180 | 40 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q6C4Y5 | 492 | DOT1_YARLI Histone-lysine N-methyltransferase... | 220 | 2e-48 | 176 | 40 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q2H9L1 | 510 | DOT1_CHAGB Histone-lysine N-methyltransferase... | 272 | 1e-47 | 175 | 36 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q4WVH4 | 502 | DOT1_ASPFU Histone-lysine N-methyltransferase... | 216 | 8e-47 | 172 | 38 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q4IJP1 | 493 | DOT1_GIBZE Histone-lysine N-methyltransferase... | 278 | 8e-47 | 172 | 36 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q7SB74 | 531 | DOT1_NEUCR Histone-lysine N-methyltransferase... | 275 | 3e-45 | 168 | 35 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q04089 | 582 | DOT1_YEAST Histone-lysine N-methyltransferase... | 279 | 6e-38 | 147 | 31 | 54 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IDA:SGD.::GO:0031493; F:nucleosomal histone binding; IDA:SGD. | | | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0070911; P:global genome nucleotide-excision repair; IMP:SGD.::GO:0000725; P:recombinational repair; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q756E1 | 575 | DOT1_ASHGO Histone-lysine N-methyltransferase... | 278 | 1e-34 | 138 | 31 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q8TEK3 | 1739 | DOT1L_HUMAN Histone-lysine N-methyltransferas... | 250 | 5e-33 | 136 | 34 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0046425; P:regulation of JAK-STAT cascade; IDA:UniProtKB.::GO:2000677; P:regulation of transcription regulatory region DNA binding; IMP:UniProtKB. | 15 | Q6CWV1 | 572 | DOT1_KLULA Histone-lysine N-methyltransferase... | 228 | 6e-33 | 133 | 34 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q6FNM5 | 652 | DOT1_CANGA Histone-lysine N-methyltransferase... | 224 | 8e-29 | 122 | 31 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q8INR6 | 1848 | DOT1L_DROME Histone-lysine N-methyltransferas... | 235 | 2e-26 | 116 | 36 | 51 | GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. | | | | | | | | | | GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IMP:UniProtKB. | | | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:UniProtKB.::GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB. | 18 | Q5A309 | 1343 | DOT1_CANAL Histone-lysine N-methyltransferase... | 243 | 1e-18 | 91.7 | 28 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q6BTC8 | 1172 | DOT1_DEBHA Histone-lysine N-methyltransferase... | 218 | 5e-16 | 83.6 | 29 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q55AX2 | 1845 | DOT1L_DICDI Histone-lysine N-methyltransferas... | 205 | 0.0000000006 | 65.1 | 28 | 45 | GO:0005634; C:nucleus; IDA:dictyBase. | | | | | | | | | | GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IDA:dictyBase. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | F6HH45 | 510 | TRM52_VITVI tRNA (guanine(37)-N1)-methyltrans... | 94 | 0.019 | 40.8 | 31 | 47 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052906; F:tRNA (guanine(37)-N(1))-methyltransferase activity; IEA:EC. | | | | | | | | | | | 22 | Q4JBL7 | 192 | CBIT_SULAC Probable cobalt-precorrin-6Y C(15)... | 69 | 0.23 | 36.6 | 35 | 49 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 23 | Q5FAH7 | 295 | PRMA_NEIG1 Ribosomal protein L11 methyltransf... | 58 | 1.3 | 34.7 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | | 24 | C3N8G6 | 199 | CBIT_SULIY Probable cobalt-precorrin-6Y C(15)... | 51 | 1.3 | 33.9 | 31 | 57 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 25 | C3MTW8 | 199 | CBIT_SULIM Probable cobalt-precorrin-6Y C(15)... | 51 | 1.3 | 33.9 | 31 | 57 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 26 | C3MJI5 | 199 | CBIT_SULIL Probable cobalt-precorrin-6Y C(15)... | 51 | 1.3 | 33.9 | 31 | 57 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 27 | C4KJM8 | 199 | CBIT_SULIK Probable cobalt-precorrin-6Y C(15)... | 51 | 1.3 | 33.9 | 31 | 57 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 28 | C3N0H8 | 199 | CBIT_SULIA Probable cobalt-precorrin-6Y C(15)... | 51 | 1.3 | 33.9 | 31 | 57 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 29 | C3NJQ5 | 199 | CBIT_SULIN Probable cobalt-precorrin-6Y C(15)... | 51 | 1.4 | 33.9 | 31 | 57 | | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW. | 30 | A1KS36 | 295 | PRMA_NEIMF Ribosomal protein L11 methyltransf... | 58 | 1.7 | 34.3 | 34 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008276; F:protein methyltransferase activity; IEA:InterPro. | | | | | | | | | | | 31 | A3MZ07 | 234 | UBIG_ACTP2 3-demethylubiquinone-9 3-methyltra... | 85 | 2 | 33.9 | 31 | 49 | | | | | | | | | | | GO:0008425; F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; IEA:InterPro.::GO:0008689; F:3-demethylubiquinone-9 3-O-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW. |