| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
901 | P51812 | 740 | KS6A3_HUMAN Ribosomal protein S6 kinase alpha... | 223 | 0.0000000000001 | 75.5 | 27 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 902 | Q6FV07 | 358 | IPL1_CANGA Spindle assembly checkpoint kinase... | 297 | 0.0000000000001 | 74.7 | 25 | 44 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 903 | Q90XF2 | 588 | KPCI_DANRE Protein kinase C iota type OS=Dani... | 218 | 0.0000000000001 | 75.5 | 28 | 49 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031226; C:intrinsic to plasma membrane; IDA:ZFIN.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005915; C:zonula adherens; IDA:ZFIN. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034334; P:adherens junction maintenance; IMP:ZFIN.::GO:0045217; P:cell-cell junction maintenance; IMP:ZFIN.::GO:0007502; P:digestive tract mesoderm development; IMP:ZFIN.::GO:0048546; P:digestive tract morphogenesis; IMP:ZFIN.::GO:0021744; P:dorsal motor nucleus of vagus nerve development; IMP:ZFIN.::GO:0035050; P:embryonic heart tube development; IMP:ZFIN.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:ZFIN.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; IMP:ZFIN.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IMP:ZFIN.::GO:0008078; P:mesodermal cell migration; IMP:ZFIN.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:ZFIN.::GO:0001841; P:neural tube formation; IGI:ZFIN.::GO:0007405; P:neuroblast proliferation; IMP:ZFIN.::GO:0007097; P:nuclear migration; IMP:ZFIN.::GO:0042476; P:odontogenesis; IMP:ZFIN.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN. | 904 | Q3U3Q1 | 472 | ULK3_MOUSE Serine/threonine-protein kinase UL... | 212 | 0.0000000000001 | 75.5 | 28 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 905 | Q1DN93 | 969 | ATG1_COCIM Serine/threonine-protein kinase AT... | 265 | 0.0000000000001 | 75.9 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 906 | Q9C098 | 648 | DCLK3_HUMAN Serine/threonine-protein kinase D... | 308 | 0.0000000000001 | 75.5 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 907 | Q9QY78 | 757 | IKKB_RAT Inhibitor of nuclear factor kappa-B ... | 211 | 0.0000000000001 | 75.5 | 27 | 47 | GO:0008385; C:IkappaB kinase complex; IDA:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0008384; F:IkappaB kinase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0003009; P:skeletal muscle contraction; IEP:RGD. | 908 | Q9BZL6 | 878 | KPCD2_HUMAN Serine/threonine-protein kinase D... | 293 | 0.0000000000001 | 75.5 | 25 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0008219; P:cell death; IMP:BHF-UCL.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0061154; P:endothelial tube morphogenesis; TAS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0050852; P:T cell receptor signaling pathway; IDA:BHF-UCL.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 909 | Q54V83 | 460 | Y9296_DICDI Probable serine/threonine-protein... | 319 | 0.0000000000001 | 75.1 | 23 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 910 | O44997 | 1425 | DAPK_CAEEL Death-associated protein kinase da... | 239 | 0.0000000000001 | 75.9 | 26 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 911 | O94168 | 619 | SNF1_CANTR Carbon catabolite-derepressing pro... | 202 | 0.0000000000001 | 75.1 | 24 | 50 | GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. | 912 | O65554 | 441 | CIPK6_ARATH CBL-interacting serine/threonine-... | 209 | 0.0000000000001 | 75.1 | 30 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0042538; P:hyperosmotic salinity response; IDA:TAIR.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 913 | Q9XUJ7 | 722 | DKF1_CAEEL Serine/threonine-protein kinase dk... | 320 | 0.0000000000001 | 75.5 | 21 | 42 | GO:0030424; C:axon; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005624; C:membrane fraction; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase. | 914 | Q6DE87 | 474 | CHK1_XENLA Serine/threonine-protein kinase Ch... | 206 | 0.0000000000001 | 75.1 | 29 | 51 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB. | 915 | O59790 | 355 | ARK1_SCHPO Serine/threonine-protein kinase ar... | 337 | 0.0000000000001 | 74.3 | 23 | 42 | GO:0032133; C:chromosome passenger complex; NAS:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0051233; C:spindle midzone; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IMP:PomBase.::GO:2000775; P:histone H3-S10 phosphorylation involved in chromosome condensation; IDA:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IGI:PomBase.::GO:0031134; P:sister chromatid biorientation; TAS:PomBase. | 916 | P25098 | 689 | ARBK1_HUMAN Beta-adrenergic receptor kinase 1... | 256 | 0.0000000000001 | 75.1 | 26 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0031694; F:alpha-2A adrenergic receptor binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; IDA:UniProtKB.::GO:0004703; F:G-protein coupled receptor kinase activity; ISS:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.::GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:BHF-UCL.::GO:0045988; P:negative regulation of striated muscle contraction; IMP:BHF-UCL.::GO:0003108; P:negative regulation of the force of heart contraction by chemical signal; IMP:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.::GO:0033605; P:positive regulation of catecholamine secretion; ISS:BHF-UCL.::GO:0031623; P:receptor internalization; IDA:UniProtKB.::GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 917 | Q15349 | 733 | KS6A2_HUMAN Ribosomal protein S6 kinase alpha... | 223 | 0.0000000000002 | 75.1 | 28 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 918 | O94806 | 890 | KPCD3_HUMAN Serine/threonine-protein kinase D... | 293 | 0.0000000000002 | 75.1 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; TAS:ProtInc. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 919 | O77708 | 533 | KCC2D_RABIT Calcium/calmodulin-dependent prot... | 300 | 0.0000000000002 | 75.1 | 24 | 47 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB. | 920 | P21146 | 689 | ARBK1_BOVIN Beta-adrenergic receptor kinase 1... | 256 | 0.0000000000002 | 75.1 | 26 | 47 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0016020; C:membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IDA:BHF-UCL.::GO:0002031; P:G-protein coupled receptor internalization; IDA:UniProtKB.::GO:0007507; P:heart development; ISS:AgBase.::GO:0006886; P:intracellular protein transport; IMP:BHF-UCL.::GO:0045988; P:negative regulation of striated muscle contraction; IMP:BHF-UCL.::GO:0003108; P:negative regulation of the force of heart contraction by chemical signal; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 921 | Q95266 | 499 | KCC2D_PIG Calcium/calmodulin-dependent protei... | 299 | 0.0000000000002 | 74.7 | 24 | 47 | GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB. | 922 | P26817 | 689 | ARBK1_RAT Beta-adrenergic receptor kinase 1 O... | 256 | 0.0000000000002 | 75.1 | 26 | 47 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0030424; C:axon; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005901; C:caveola; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045202; C:synapse; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IDA:RGD.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IDA:BHF-UCL.::GO:0042699; P:follicle-stimulating hormone signaling pathway; IDA:RGD.::GO:0033605; P:positive regulation of catecholamine secretion; IDA:BHF-UCL.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 923 | O88351 | 757 | IKKB_MOUSE Inhibitor of nuclear factor kappa-... | 211 | 0.0000000000002 | 75.1 | 27 | 46 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; TAS:MGI.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008384; F:IkappaB kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; TAS:MGI. | | | | | | | | | | GO:0001782; P:B cell homeostasis; IMP:MGI. | 924 | P34208 | 496 | CHK1_SCHPO Serine/threonine-protein kinase ch... | 210 | 0.0000000000002 | 74.7 | 25 | 50 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005654; C:nucleoplasm; TAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000077; P:DNA damage checkpoint; IGI:PomBase. | 925 | Q66JF3 | 417 | MKNK1_XENTR MAP kinase-interacting serine/thr... | 309 | 0.0000000000002 | 74.7 | 24 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 926 | P45894 | 589 | AAPK1_CAEEL 5'-AMP-activated protein kinase c... | 204 | 0.0000000000002 | 74.7 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase. | 927 | Q7TSC3 | 627 | NEK5_MOUSE Serine/threonine-protein kinase Ne... | 213 | 0.0000000000002 | 75.1 | 23 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 928 | P15791 | 533 | KCC2D_RAT Calcium/calmodulin-dependent protei... | 299 | 0.0000000000002 | 74.7 | 24 | 47 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB. | 929 | A4QXX4 | 499 | SSN3_MAGO7 Serine/threonine-protein kinase SS... | 224 | 0.0000000000002 | 74.7 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 930 | Q7RJG2 | 528 | CDPK4_PLAYO Calcium-dependent protein kinase ... | 333 | 0.0000000000002 | 74.7 | 24 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 931 | Q99MK8 | 689 | ARBK1_MOUSE Beta-adrenergic receptor kinase 1... | 256 | 0.0000000000002 | 74.7 | 26 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IMP:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. |
