| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
841 | A8WXF6 | 533 | KCC2D_CAEBR Calcium/calmodulin-dependent prot... | 298 | 0.00000000000003 | 77 | 24 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 842 | Q6FKC6 | 567 | SSN3_CANGA Serine/threonine-protein kinase SS... | 220 | 0.00000000000003 | 77 | 29 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 843 | P49137 | 400 | MAPK2_HUMAN MAP kinase-activated protein kina... | 299 | 0.00000000000003 | 76.6 | 24 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 844 | Q9LGV5 | 461 | CIPK1_ORYSJ CBL-interacting protein kinase 1 ... | 210 | 0.00000000000003 | 77 | 32 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 845 | O55173 | 559 | PDPK1_RAT 3-phosphoinositide-dependent protei... | 309 | 0.00000000000003 | 77 | 25 | 44 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 846 | O35280 | 476 | CHK1_MOUSE Serine/threonine-protein kinase Ch... | 213 | 0.00000000000003 | 77 | 29 | 50 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005657; C:replication fork; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:MGI.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; IDA:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:UniProtKB. | 847 | P49759 | 484 | CLK1_HUMAN Dual specificity protein kinase CL... | 330 | 0.00000000000003 | 77 | 24 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB. | 848 | P49139 | 366 | MAPK2_RABIT MAP kinase-activated protein kina... | 313 | 0.00000000000003 | 76.3 | 24 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB. | 849 | P0C661 | 612 | CDK8_CAEBR Cyclin-dependent kinase 8 OS=Caeno... | 329 | 0.00000000000003 | 77 | 24 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 850 | Q39193 | 361 | SRK2I_ARATH Serine/threonine-protein kinase S... | 257 | 0.00000000000004 | 76.3 | 26 | 48 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IGI:TAIR.::GO:0010029; P:regulation of seed germination; IGI:TAIR.::GO:0009739; P:response to gibberellin stimulus; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR. | 851 | O08679 | 722 | MARK2_RAT Serine/threonine-protein kinase MAR... | 206 | 0.00000000000004 | 77 | 24 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 852 | O43293 | 454 | DAPK3_HUMAN Death-associated protein kinase 3... | 228 | 0.00000000000004 | 76.6 | 25 | 49 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0007088; P:regulation of mitosis; TAS:UniProtKB.::GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 853 | Q91821 | 651 | MELK_XENLA Maternal embryonic leucine zipper ... | 241 | 0.00000000000004 | 76.6 | 27 | 49 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 854 | Q13131 | 559 | AAPK1_HUMAN 5'-AMP-activated protein kinase c... | 208 | 0.00000000000004 | 76.6 | 26 | 48 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; NAS:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; NAS:UniProtKB.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046318; P:negative regulation of glucosylceramide biosynthetic process; NAS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; NAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045542; P:positive regulation of cholesterol biosynthetic process; NAS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; NAS:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 855 | Q5PU49 | 674 | KPCD_CANFA Protein kinase C delta type OS=Can... | 222 | 0.00000000000004 | 76.6 | 27 | 47 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB. | 856 | Q5RDH5 | 554 | AAPK1_PONAB 5'-AMP-activated protein kinase c... | 208 | 0.00000000000004 | 76.6 | 26 | 48 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 857 | Q1EG27 | 1305 | MYO3B_MOUSE Myosin-IIIb OS=Mus musculus (Mous... | 217 | 0.00000000000004 | 77 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 858 | P42818 | 465 | KPK1_ARATH Serine/threonine-protein kinase At... | 232 | 0.00000000000004 | 76.3 | 26 | 46 | GO:0005737; C:cytoplasm; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR. | 859 | P54735 | 505 | SPKD_SYNY3 Serine/threonine-protein kinase D ... | 229 | 0.00000000000005 | 76.6 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 860 | Q9Y7J6 | 550 | PPK21_SCHPO Serine/threonine-protein kinase p... | 221 | 0.00000000000005 | 76.6 | 30 | 48 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; TAS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 861 | Q15139 | 912 | KPCD1_HUMAN Serine/threonine-protein kinase D... | 291 | 0.00000000000005 | 76.6 | 25 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IMP:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IMP:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0045806; P:negative regulation of endocytosis; TAS:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.::GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.::GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IGI:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:BHF-UCL.::GO:2001044; P:regulation of integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 862 | Q5EG47 | 559 | AAPK1_MOUSE 5'-AMP-activated protein kinase c... | 208 | 0.00000000000005 | 76.6 | 26 | 48 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0035174; F:histone serine kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0019395; P:fatty acid oxidation; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; IDA:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 863 | P54645 | 559 | AAPK1_RAT 5'-AMP-activated protein kinase cat... | 208 | 0.00000000000005 | 76.3 | 26 | 48 | GO:0031588; C:AMP-activated protein kinase complex; IDA:UniProtKB.::GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042557; F:eukaryotic elongation factor-2 kinase activator activity; NAS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0071361; P:cellular response to ethanol; IEP:RGD.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; NAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:RGD.::GO:0046321; P:positive regulation of fatty acid oxidation; NAS:UniProtKB.::GO:0045722; P:positive regulation of gluconeogenesis; NAS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; NAS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060627; P:regulation of vesicle-mediated transport; IMP:RGD.::GO:0014823; P:response to activity; IDA:RGD.::GO:0031000; P:response to caffeine; IDA:RGD.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 864 | Q9WTQ1 | 918 | KPCD1_RAT Serine/threonine-protein kinase D1 ... | 291 | 0.00000000000005 | 76.6 | 25 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB. | 865 | Q5XIS9 | 875 | KPCD2_RAT Serine/threonine-protein kinase D2 ... | 293 | 0.00000000000005 | 76.6 | 25 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB. | 866 | P49657 | 908 | MNB_DROME Serine/threonine-protein kinase min... | 242 | 0.00000000000005 | 76.6 | 27 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IGI:FlyBase.::GO:0007399; P:nervous system development; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0007632; P:visual behavior; IMP:FlyBase. | 867 | A8WRV1 | 813 | KIN29_CAEBR Serine/threonine-protein kinase k... | 205 | 0.00000000000005 | 76.6 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 868 | Q55FT4 | 2247 | TSUA_DICDI Probable serine/threonine-protein ... | 252 | 0.00000000000005 | 77 | 25 | 50 | GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. | 869 | Q8BZ03 | 875 | KPCD2_MOUSE Serine/threonine-protein kinase D... | 293 | 0.00000000000005 | 76.6 | 25 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; IDA:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; IMP:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB. | 870 | Q62101 | 918 | KPCD1_MOUSE Serine/threonine-protein kinase D... | 291 | 0.00000000000005 | 76.6 | 25 | 45 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; IMP:UniProtKB. | 871 | Q6P3R8 | 708 | NEK5_HUMAN Serine/threonine-protein kinase Ne... | 217 | 0.00000000000005 | 76.6 | 23 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
