| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
841 | O43318 | 606 | M3K7_HUMAN Mitogen-activated protein kinase k... | 325 | 0.00000000000005 | 78.6 | 24 | 42 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0007252; P:I-kappaB phosphorylation; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 842 | Q8BYR2 | 1129 | LATS1_MOUSE Serine/threonine-protein kinase L... | 227 | 0.00000000000005 | 79.3 | 26 | 45 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.::GO:0000819; P:sister chromatid segregation; ISS:UniProtKB. | 843 | P0C8E4 | 606 | M3K7_RAT Mitogen-activated protein kinase kin... | 325 | 0.00000000000005 | 78.6 | 24 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 844 | A2VDU3 | 579 | M3K7_BOVIN Mitogen-activated protein kinase k... | 325 | 0.00000000000005 | 78.6 | 24 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 845 | Q5RFL3 | 606 | M3K7_PONAB Mitogen-activated protein kinase k... | 325 | 0.00000000000005 | 78.6 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 846 | Q5RCC4 | 478 | KCC2A_PONAB Calcium/calmodulin-dependent prot... | 311 | 0.00000000000005 | 78.2 | 24 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 847 | Q9UQM7 | 478 | KCC2A_HUMAN Calcium/calmodulin-dependent prot... | 311 | 0.00000000000005 | 78.2 | 24 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 848 | P22204 | 572 | DBF2_YEAST Cell cycle protein kinase DBF2 OS=... | 263 | 0.00000000000005 | 78.6 | 25 | 43 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.::GO:0005773; C:vacuole; IMP:GOC. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000280; P:nuclear division; IMP:SGD.::GO:0007035; P:vacuolar acidification; IMP:SGD. | 849 | Q62073 | 579 | M3K7_MOUSE Mitogen-activated protein kinase k... | 325 | 0.00000000000005 | 78.6 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004708; F:MAP kinase kinase activity; IDA:MGI.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0060546; P:negative regulation of necroptosis; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0001841; P:neural tube formation; IMP:MGI.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:MGI. | 850 | P11345 | 648 | RAF1_RAT RAF proto-oncogene serine/threonine-... | 329 | 0.00000000000005 | 78.6 | 23 | 40 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IMP:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0007507; P:heart development; IEP:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD. | 851 | P11275 | 478 | KCC2A_RAT Calcium/calmodulin-dependent protei... | 311 | 0.00000000000005 | 78.2 | 24 | 41 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032839; C:dendrite cytoplasm; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:UniProtKB. | 852 | P11798 | 478 | KCC2A_MOUSE Calcium/calmodulin-dependent prot... | 311 | 0.00000000000005 | 78.2 | 24 | 41 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:MGI.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:MGI. | 853 | Q0U4L8 | 355 | HOG1_PHANO Mitogen-activated protein kinase H... | 340 | 0.00000000000005 | 77 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 854 | P29323 | 1055 | EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo ... | 247 | 0.00000000000006 | 79 | 25 | 43 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0071679; P:commissural neuron axon guidance; ISS:UniProtKB.::GO:0022038; P:corpus callosum development; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0050878; P:regulation of body fluid levels; ISS:UniProtKB.::GO:0001655; P:urogenital system development; ISS:UniProtKB. | 855 | P16912 | 583 | KDC2_DROME Protein kinase DC2 OS=Drosophila m... | 259 | 0.00000000000006 | 78.6 | 22 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase. | 856 | Q6C7U8 | 294 | PHO85_YARLI Negative regulator of the PHO sys... | 253 | 0.00000000000006 | 76.3 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 857 | Q92241 | 304 | PHO85_KLULA Negative regulator of the PHO sys... | 279 | 0.00000000000006 | 76.3 | 28 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 858 | P54644 | 444 | KRAC_DICDI RAC family serine/threonine-protei... | 247 | 0.00000000000006 | 77.8 | 24 | 44 | GO:0005938; C:cell cortex; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase. | 859 | P08069 | 1367 | IGF1R_HUMAN Insulin-like growth factor 1 rece... | 321 | 0.00000000000006 | 79 | 22 | 42 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0043559; F:insulin binding; IPI:BHF-UCL.::GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.::GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0006955; P:immune response; IMP:BHF-UCL.::GO:0051389; P:inactivation of MAPKK activity; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IC:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB. | 860 | O13310 | 469 | ORB6_SCHPO Serine/threonine-protein kinase or... | 284 | 0.00000000000006 | 77.8 | 26 | 41 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0000078; P:cell shape checkpoint; NAS:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 861 | Q69Z98 | 735 | BRSK2_MOUSE Serine/threonine-protein kinase B... | 310 | 0.00000000000006 | 78.6 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IC:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI. | 862 | P57059 | 783 | SIK1_HUMAN Serine/threonine-protein kinase SI... | 302 | 0.00000000000006 | 78.6 | 25 | 39 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.::GO:0072333; P:signal transduction by p53 class mediator resulting in induction of anoikis; IMP:BHF-UCL. | 863 | Q9KIG4 | 641 | PK1_STRTO Serine/threonine-protein kinase PK-... | 235 | 0.00000000000007 | 78.2 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 864 | Q4R8E0 | 631 | E2AK1_MACFA Eukaryotic translation initiation... | 201 | 0.00000000000007 | 78.2 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:InterPro. | 865 | Q54TM7 | 1288 | DRKD_DICDI Probable serine/threonine-protein ... | 314 | 0.00000000000007 | 79 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 866 | P00546 | 298 | CDK1_YEAST Cyclin-dependent kinase 1 OS=Sacch... | 267 | 0.00000000000007 | 75.9 | 25 | 41 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:SGD.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:SGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:SGD.::GO:0010571; P:positive regulation of DNA replication involved in S phase; IMP:SGD.::GO:0051446; P:positive regulation of meiotic cell cycle; IDA:SGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:SGD.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:SGD.::GO:0010898; P:positive regulation of triglyceride catabolic process; IMP:SGD.::GO:0010568; P:regulation of budding cell apical bud growth; IMP:SGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:SGD.::GO:0010570; P:regulation of filamentous growth; IMP:SGD. | 867 | P24062 | 1370 | IGF1R_RAT Insulin-like growth factor 1 recept... | 319 | 0.00000000000007 | 79 | 22 | 42 | GO:0005901; C:caveola; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0001965; F:G-protein alpha-subunit binding; IPI:RGD.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:RGD.::GO:0030010; P:establishment of cell polarity; IMP:RGD.::GO:0051389; P:inactivation of MAPKK activity; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0032467; P:positive regulation of cytokinesis; IMP:RGD.::GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051262; P:protein tetramerization; ISS:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:0033197; P:response to vitamin E; IEP:RGD. | 868 | Q5I6M2 | 329 | HOG1_SETTU Mitogen-activated protein kinase H... | 285 | 0.00000000000007 | 76.3 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 869 | P11837 | 699 | NIMA_EMENI G2-specific protein kinase nimA OS... | 350 | 0.00000000000007 | 78.2 | 23 | 37 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 870 | O95835 | 1130 | LATS1_HUMAN Serine/threonine-protein kinase L... | 226 | 0.00000000000008 | 78.6 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051220; P:cytoplasmic sequestering of protein; IMP:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; IDA:BHF-UCL.::GO:0009755; P:hormone-mediated signaling pathway; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0000819; P:sister chromatid segregation; IDA:UniProtKB. | 871 | P54763 | 994 | EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus m... | 247 | 0.00000000000008 | 78.6 | 25 | 43 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0007413; P:axonal fasciculation; IMP:UniProtKB.::GO:0071679; P:commissural neuron axon guidance; IMP:UniProtKB.::GO:0022038; P:corpus callosum development; IMP:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; IMP:UniProtKB.::GO:0042472; P:inner ear morphogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; IDA:UniProtKB.::GO:0050878; P:regulation of body fluid levels; IMP:UniProtKB.::GO:0001655; P:urogenital system development; IMP:UniProtKB. |
