Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Agaricus bisporus bisporus H97
Locus:
189979
Length:
581
Number of sequences:
10438
Description:
estExt_fgenesh2_kg.C_10866
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
811Q6DEH3    491   KC2D1_DANRE Calcium/calmodulin-dependent prot...3170.00000000000003     79     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
812Q38997    535   KIN10_ARATH SNF1-related protein kinase catal...3170.00000000000003     79.3     22     41GO:0000152; C:nuclear ubiquitin ligase complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0009594; P:detection of nutrient; IDA:TAIR.::GO:0003006; P:developmental process involved in reproduction; IMP:TAIR.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0010260; P:organ senescence; IMP:TAIR.::GO:0080022; P:primary root development; IMP:TAIR.::GO:0006950; P:response to stress; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; IMP:TAIR.::GO:0010050; P:vegetative phase change; IMP:TAIR.
813Q3MHJ9    542   KCC2B_BOVIN Calcium/calmodulin-dependent prot...3200.00000000000003     79.3     24     39GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
814Q5R8X7    966   M3K13_PONAB Mitogen-activated protein kinase ...1980.00000000000003     79.7     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
815Q55GS4    366   CDK10_DICDI Probable cyclin-dependent kinase ...2940.00000000000003     78.2     26     40GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
816A8XJL7    472   SAX1_CAEBR Serine/threonine-protein kinase sa...2310.00000000000003     79     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
817P46734    347   MP2K3_HUMAN Dual specificity mitogen-activate...2000.00000000000003     77.8     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
818P51958    302   CDK1_CARAU Cyclin-dependent kinase 1 OS=Caras...3370.00000000000003     77     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
819P29318    983   EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallu...3060.00000000000003     79.7     25     40GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
820Q2RBE3    622   WNK7_ORYSJ Probable serine/threonine-protein ...2620.00000000000003     79.3     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
821P53683    533   CDPK2_ORYSJ Calcium-dependent protein kinase ...3130.00000000000004     79     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
822P00530    873   FPS_FUJSV Tyrosine-protein kinase transformin...3230.00000000000004     79.3     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:InterPro.::GO:0016032; P:viral reproduction; IEA:InterPro.
823Q558U1    2258   IFKA_DICDI Probable serine/threonine-protein ...2070.00000000000004     79.7     29     48GO:0005622; C:intracellular; IC:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IMP:dictyBase.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IMP:dictyBase.::GO:0016337; P:cell-cell adhesion; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase.::GO:0048255; P:mRNA stabilization; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0006446; P:regulation of translational initiation; ISS:dictyBase.
824Q55EI8    1385   Y9956_DICDI Probable serine/threonine-protein...2460.00000000000004     79.7     25     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
825O88831    587   KKCC2_RAT Calcium/calmodulin-dependent protei...1990.00000000000004     79     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.::GO:0030295; F:protein kinase activator activity; TAS:RGD.
GO:0032147; P:activation of protein kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
826Q8C078    588   KKCC2_MOUSE Calcium/calmodulin-dependent prot...1990.00000000000004     79     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
827Q6CFS5    588   CBK1_YARLI Serine/threonine-protein kinase CB...2220.00000000000004     79     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
828O14098    593   CTK1_SCHPO CTD kinase subunit alpha OS=Schizo...2830.00000000000004     79     25     40GO:0005730; C:nucleolus; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0031566; P:contractile ring maintenance involved in cell cycle cytokinesis; IMP:PomBase.::GO:0031565; P:cytokinesis checkpoint; IMP:PomBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; IGI:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
829Q9HGY5    326   PHO85_CANAX Negative regulator of the PHO sys...3390.00000000000004     77     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
830A7F0W2    951   ATG1_SCLS1 Serine/threonine-protein kinase AT...3260.00000000000004     79.3     24     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
831Q622Z7    640   GRK1_CAEBR G protein-coupled receptor kinase ...2620.00000000000004     79     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
832Q12706    436   PSK1_SCHPO Serine/threonine-protein kinase ps...2480.00000000000004     78.2     24     44GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007165; P:signal transduction; IC:PomBase.
833Q6PHR2    472   ULK3_HUMAN Serine/threonine-protein kinase UL...3150.00000000000004     78.6     23     43GO:0000407; C:pre-autophagosomal structure; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; TAS:UniProtKB.::GO:0090398; P:cellular senescence; TAS:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
834Q90344    987   EPHB2_COTJA Ephrin type-B receptor 2 OS=Cotur...2470.00000000000004     79.3     26     42GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB.
GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.
835Q28GW8    652   MELK_XENTR Maternal embryonic leucine zipper ...3040.00000000000004     79     25     39GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
836P04412    1426   EGFR_DROME Epidermal growth factor receptor O...3500.00000000000004     79.3     26     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005006; F:epidermal growth factor-activated receptor activity; TAS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007469; P:antennal development; NAS:FlyBase.::GO:0006916; P:anti-apoptosis; NAS:FlyBase.::GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007420; P:brain development; TAS:FlyBase.::GO:0046845; P:branched duct epithelial cell fate determination, open tracheal system; TAS:FlyBase.::GO:0030031; P:cell projection assembly; IMP:FlyBase.::GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IGI:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0001752; P:compound eye photoreceptor fate commitment; TAS:FlyBase.::GO:0035225; P:determination of genital disc primordium; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0061331; P:epithelial cell proliferation involved in Malpighian tubule morphogenesis; IMP:FlyBase.::GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IMP:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0048139; P:female germ-line cyst encapsulation; TAS:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:FlyBase.::GO:0007369; P:gastrulation; TAS:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IGI:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0007482; P:haltere development; IMP:FlyBase.::GO:0003015; P:heart process; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; TAS:FlyBase.::GO:0007479; P:leg disc proximal/distal pattern formation; IMP:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0048140; P:male germ-line cyst encapsulation; TAS:FlyBase.::GO:0008071; P:maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded; IMP:FlyBase.::GO:0016203; P:muscle attachment; TAS:FlyBase.::GO:0042694; P:muscle cell fate specification; TAS:FlyBase.::GO:0046673; P:negative regulation of compound eye retinal cell programmed cell death; IMP:FlyBase.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IMP:FlyBase.::GO:0035310; P:notum cell fate specification; IMP:FlyBase.::GO:0007477; P:notum development; IMP:FlyBase.::GO:0001742; P:oenocyte differentiation; TAS:FlyBase.::GO:0016318; P:ommatidial rotation; IMP:FlyBase.::GO:0007314; P:oocyte anterior/posterior axis specification; NAS:FlyBase.::GO:0007310; P:oocyte dorsal/ventral axis specification; NAS:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0007458; P:progression of morphogenetic furrow involved in compound eye morphogenesis; TAS:FlyBase.::GO:0045466; P:R7 cell differentiation; TAS:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0045468; P:regulation of R8 cell spacing in compound eye; NAS:FlyBase.::GO:0007431; P:salivary gland development; IMP:FlyBase.::GO:0016330; P:second mitotic wave involved in compound eye morphogenesis; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.::GO:0035277; P:spiracle morphogenesis, open tracheal system; IMP:FlyBase.::GO:0048865; P:stem cell fate commitment; IMP:FlyBase.::GO:0007421; P:stomatogastric nervous system development; TAS:FlyBase.::GO:0035202; P:tracheal pit formation in open tracheal system; TAS:FlyBase.::GO:0007473; P:wing disc proximal/distal pattern formation; TAS:FlyBase.
837Q2LZZ7    458   TRC_DROPS Serine/threonine-protein kinase tri...2270.00000000000004     78.2     26     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0050773; P:regulation of dendrite development; ISS:UniProtKB.
838Q8RWC9    444   CIPK1_ARATH CBL-interacting serine/threonine-...2650.00000000000005     78.2     25     43GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
839Q61UC4    811   KRAF1_CAEBR Raf homolog serine/threonine-prot...3140.00000000000005     79     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
840Q54P47    1335   NDRC_DICDI Probable serine/threonine-protein ...2830.00000000000005     79.3     24     43GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
841O43318    606   M3K7_HUMAN Mitogen-activated protein kinase k...3250.00000000000005     78.6     24     42GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0007252; P:I-kappaB phosphorylation; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
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