| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q5RBJ6 | 431 | STRAA_PONAB STE20-related kinase adapter prot... | 397 | 2e-26 | 115 | 25 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB. | 182 | Q54MY9 | 860 | MKCA_DICDI Probable serine/threonine-protein ... | 253 | 2e-26 | 118 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0045595; P:regulation of cell differentiation; IGI:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 183 | Q4R6X5 | 394 | STRAA_MACFA STE20-related kinase adapter prot... | 397 | 2e-26 | 114 | 26 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB. | 184 | Q9S7U9 | 363 | M2K2_ARATH Mitogen-activated protein kinase k... | 313 | 3e-26 | 114 | 29 | 45 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009631; P:cold acclimation; IMP:TAIR.::GO:0009814; P:defense response, incompatible interaction; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR. | 185 | Q55CE0 | 677 | MKCF_DICDI Probable serine/threonine-protein ... | 267 | 4e-26 | 116 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 186 | Q08942 | 431 | NRKA_TRYBB Putative serine/threonine-protein ... | 279 | 5e-26 | 114 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 187 | Q5ZK47 | 389 | STRAA_CHICK STE20-related kinase adapter prot... | 357 | 7e-26 | 113 | 26 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004672; F:protein kinase activity; IEA:InterPro. | | | | | | | | | | GO:0032147; P:activation of protein kinase activity; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB. | 188 | Q16W24 | 769 | PLK4_AEDAE Serine/threonine-protein kinase PL... | 315 | 7e-26 | 116 | 26 | 43 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 189 | A5GFW1 | 402 | AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)... | 355 | 2e-25 | 112 | 26 | 43 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 190 | P46549 | 982 | SULU_CAEEL Serine/threonine-protein kinase SU... | 334 | 4e-25 | 114 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 191 | Q12701 | 592 | KSG1_SCHPO Serine/threonine-protein kinase ks... | 329 | 5e-25 | 113 | 27 | 44 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 192 | P32491 | 506 | MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Sa... | 283 | 5e-25 | 112 | 30 | 47 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030242; P:peroxisome degradation; IGI:SGD.::GO:0007165; P:signal transduction; IMP:SGD. | 193 | Q13163 | 448 | MP2K5_HUMAN Dual specificity mitogen-activate... | 311 | 1e-24 | 110 | 30 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.::GO:0071363; P:cellular response to growth factor stimulus; ISS:BHF-UCL.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; ISS:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; ISS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; ISS:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL. | 194 | Q2TA06 | 402 | AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo... | 342 | 1e-24 | 109 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 195 | Q03428 | 431 | NRKB_TRYBB Putative serine/threonine-protein ... | 280 | 1e-24 | 110 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 196 | P31325 | 406 | PHKG2_RAT Phosphorylase b kinase gamma cataly... | 403 | 1e-24 | 109 | 27 | 42 | GO:0005964; C:phosphorylase kinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0019899; F:enzyme binding; IDA:RGD.::GO:0004689; F:phosphorylase kinase activity; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:InterPro. | 197 | Q9SZ67 | 1895 | WRK19_ARATH Probable WRKY transcription facto... | 269 | 2e-24 | 112 | 31 | 45 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 198 | Q54RZ7 | 1634 | Y1199_DICDI Probable serine/threonine-protein... | 267 | 3e-24 | 112 | 30 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 199 | Q9LWM4 | 461 | CIPK5_ORYSJ CBL-interacting protein kinase 5 ... | 394 | 3e-24 | 109 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 200 | Q13233 | 1512 | M3K1_HUMAN Mitogen-activated protein kinase k... | 310 | 4e-24 | 111 | 29 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 201 | Q62862 | 448 | MP2K5_RAT Dual specificity mitogen-activated ... | 311 | 4e-24 | 108 | 30 | 44 | GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; IC:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IMP:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IMP:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:RGD.::GO:0051247; P:positive regulation of protein metabolic process; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL. | 202 | Q6X4A2 | 449 | CIPKV_ORYSJ CBL-interacting protein kinase 31... | 315 | 5e-24 | 108 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 203 | Q8TD19 | 979 | NEK9_HUMAN Serine/threonine-protein kinase Ne... | 278 | 5e-24 | 110 | 25 | 45 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 204 | Q9WVS7 | 448 | MP2K5_MOUSE Dual specificity mitogen-activate... | 311 | 5e-24 | 108 | 30 | 44 | GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007507; P:heart development; IMP:MGI. | 205 | Q54WX4 | 384 | AURK_DICDI Aurora kinase OS=Dictyostelium dis... | 324 | 6e-24 | 107 | 28 | 41 | GO:0005813; C:centrosome; IDA:dictyBase.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IDA:dictyBase.::GO:0051233; C:spindle midzone; IDA:dictyBase.::GO:0000922; C:spindle pole; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000278; P:mitotic cell cycle; ISS:dictyBase. | 206 | P0C8M8 | 626 | CCR1_MAIZE Probable serine/threonine-protein ... | 354 | 7e-24 | 109 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 207 | P53349 | 1493 | M3K1_MOUSE Mitogen-activated protein kinase k... | 310 | 1e-23 | 110 | 29 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL. | 208 | P28829 | 659 | BYR2_SCHPO Protein kinase byr2 OS=Schizosacch... | 270 | 1e-23 | 109 | 28 | 45 | GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; TAS:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 209 | B4KYX8 | 778 | PLK4_DROMO Serine/threonine-protein kinase PL... | 309 | 1e-23 | 109 | 25 | 42 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 210 | O14965 | 403 | AURKA_HUMAN Aurora kinase A OS=Homo sapiens (... | 329 | 1e-23 | 106 | 26 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0031616; C:spindle pole centrosome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB. | 211 | A2ZMH2 | 591 | NEK2_ORYSI Serine/threonine-protein kinase Ne... | 264 | 2e-23 | 108 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |
